|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 43708 |
FusionGeneSummary for ZNF787_POMT2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ZNF787_POMT2 | Fusion gene ID: 43708 | Hgene | Tgene | Gene symbol | ZNF787 | POMT2 | Gene ID | 126208 | 29954 |
| Gene name | zinc finger protein 787 | protein O-mannosyltransferase 2 | |
| Synonyms | TIP20 | LGMD2N|MDDGA2|MDDGB2|MDDGC2 | |
| Cytomap | 19q13.43 | 14q24.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | zinc finger protein 787TTF-I-interacting peptide 20transcription termination factor I interacting peptide 20 | protein O-mannosyl-transferase 2dolichyl-phosphate-mannose--protein mannosyltransferase 2 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q6DD87 | Q9UKY4 | |
| Ensembl transtripts involved in fusion gene | ENST00000270459, ENST00000587279, | ENST00000261534, ENST00000556880, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 4 X 4 X 3=48 |
| # samples | 3 | 6 | |
| ** MAII score | log2(3/1*10)=4.90689059560852 | log2(6/48*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: ZNF787 [Title/Abstract] AND POMT2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BF871714 | ZNF787 | chr19 | 56611319 | + | POMT2 | chr14 | 77751311 | + | ||
| ChiTaRS3.1 | BF871707 | ZNF787 | chr19 | 56611319 | + | POMT2 | chr14 | 77751311 | + | ||
| ChiTaRS3.1 | BF871706 | ZNF787 | chr19 | 56611319 | + | POMT2 | chr14 | 77751311 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000270459 | ENST00000261534 | ZNF787 | chr19 | 56611319 | + | POMT2 | chr14 | 77751311 | + |
| intron-intron | ENST00000270459 | ENST00000556880 | ZNF787 | chr19 | 56611319 | + | POMT2 | chr14 | 77751311 | + |
| intron-3CDS | ENST00000587279 | ENST00000261534 | ZNF787 | chr19 | 56611319 | + | POMT2 | chr14 | 77751311 | + |
| intron-intron | ENST00000587279 | ENST00000556880 | ZNF787 | chr19 | 56611319 | + | POMT2 | chr14 | 77751311 | + |
Top |
FusionProtFeatures for ZNF787_POMT2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ZNF787 | POMT2 |