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Fusion gene ID: 43683

FusionGeneSummary for ZNF763_TEX101

Fusion gene summary

Fusion gene information	Fusion gene name: ZNF763_TEX101
	Fusion gene ID: 43683
		Hgene	Tgene
	Gene symbol	ZNF763	TEX101
	Gene ID	284390	83639
	Gene name	zinc finger protein 763	testis expressed 101
	Synonyms	ZNF\|ZNF440L	CT131\|GTPR867\|NYD-SP8\|PRO1884\|SGRG\|SPATA44\|TES101RP
	Cytomap	19p13.2	19q13.31
	Type of gene	protein-coding	protein-coding
	Description	zinc finger protein 763DNA-binding proteinzinc finger protein 440 like	testis-expressed protein 101cancer/testis antigen 131cell surface receptor NYD-SP8scleroderma-associated autoantigenspermatogenesis associated 44spermatogenesis-related gene proteintestis expressed sequence 101testis-expressed sequence 101 protein
	Modification date	20180522	20180522
	UniProtAcc	Q0D2J5	Q9BY14
	Ensembl transtripts involved in fusion gene	ENST00000590798, ENST00000538752, ENST00000591944, ENST00000592625, ENST00000545530, ENST00000343949, ENST00000358987,	ENST00000602198, ENST00000253435, ENST00000601707, ENST00000598265,
Fusion gene scores	* DoF score	3 X 2 X 3=18	4 X 3 X 3=36
	# samples	3	3
	** MAII score	log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(3/36*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: ZNF763 [Title/Abstract] AND TEX101 [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
TCGA	RV	CESC	TCGA-VS-A8Q9-01A	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
In-frame	ENST00000590798	ENST00000602198	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
In-frame	ENST00000590798	ENST00000253435	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
5CDS-3UTR	ENST00000590798	ENST00000601707	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
5CDS-5UTR	ENST00000590798	ENST00000598265	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
In-frame	ENST00000538752	ENST00000602198	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
In-frame	ENST00000538752	ENST00000253435	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
5CDS-3UTR	ENST00000538752	ENST00000601707	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
5CDS-5UTR	ENST00000538752	ENST00000598265	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
In-frame	ENST00000591944	ENST00000602198	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
In-frame	ENST00000591944	ENST00000253435	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
5CDS-3UTR	ENST00000591944	ENST00000601707	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
5CDS-5UTR	ENST00000591944	ENST00000598265	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
intron-3CDS	ENST00000592625	ENST00000602198	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
intron-3CDS	ENST00000592625	ENST00000253435	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
intron-3UTR	ENST00000592625	ENST00000601707	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
intron-5UTR	ENST00000592625	ENST00000598265	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
intron-3CDS	ENST00000545530	ENST00000602198	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
intron-3CDS	ENST00000545530	ENST00000253435	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
intron-3UTR	ENST00000545530	ENST00000601707	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
intron-5UTR	ENST00000545530	ENST00000598265	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
intron-3CDS	ENST00000343949	ENST00000602198	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
intron-3CDS	ENST00000343949	ENST00000253435	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
intron-3UTR	ENST00000343949	ENST00000601707	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
intron-5UTR	ENST00000343949	ENST00000598265	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
intron-3CDS	ENST00000358987	ENST00000602198	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
intron-3CDS	ENST00000358987	ENST00000253435	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
intron-3UTR	ENST00000358987	ENST00000601707	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+
intron-5UTR	ENST00000358987	ENST00000598265	ZNF763	chr19	12036088	+	TEX101	chr19	43920033	+

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FusionProtFeatures for ZNF763_TEX101

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
ZNF763 Q0D2J5	TEX101 Q9BY14

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Fusion gene ID: 43683

FusionGeneSummary for ZNF763_TEX101

FusionProtFeatures for ZNF763_TEX101