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Fusion gene ID: 43281 |
FusionGeneSummary for ZNF410_ANKS3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ZNF410_ANKS3 | Fusion gene ID: 43281 | Hgene | Tgene | Gene symbol | ZNF410 | ANKS3 | Gene ID | 57862 | 124401 |
| Gene name | zinc finger protein 410 | ankyrin repeat and sterile alpha motif domain containing 3 | |
| Synonyms | APA-1|APA1 | - | |
| Cytomap | 14q24.3 | 16p13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | zinc finger protein 410another partner for ARF 1clones 23667 and 23775 zinc finger proteinzinc finger protein APA-1 | ankyrin repeat and SAM domain-containing protein 3 | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q86VK4 | Q6ZW76 | |
| Ensembl transtripts involved in fusion gene | ENST00000540593, ENST00000324593, ENST00000412490, ENST00000442160, ENST00000555044, ENST00000334521, ENST00000556797, | ENST00000446014, ENST00000304283, ENST00000585773, ENST00000450067, ENST00000592711, | |
| Fusion gene scores | * DoF score | 4 X 4 X 4=64 | 1 X 1 X 1=1 |
| # samples | 4 | 1 | |
| ** MAII score | log2(4/64*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: ZNF410 [Title/Abstract] AND ANKS3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LIHC | TCGA-BC-A3KG-01A | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000540593 | ENST00000446014 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000540593 | ENST00000304283 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000540593 | ENST00000585773 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000540593 | ENST00000450067 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000540593 | ENST00000592711 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000324593 | ENST00000446014 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000324593 | ENST00000304283 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000324593 | ENST00000585773 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000324593 | ENST00000450067 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000324593 | ENST00000592711 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 3UTR-3CDS | ENST00000412490 | ENST00000446014 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 3UTR-3CDS | ENST00000412490 | ENST00000304283 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 3UTR-3CDS | ENST00000412490 | ENST00000585773 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 3UTR-intron | ENST00000412490 | ENST00000450067 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 3UTR-intron | ENST00000412490 | ENST00000592711 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000442160 | ENST00000446014 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000442160 | ENST00000304283 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000442160 | ENST00000585773 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000442160 | ENST00000450067 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000442160 | ENST00000592711 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000555044 | ENST00000446014 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000555044 | ENST00000304283 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000555044 | ENST00000585773 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000555044 | ENST00000450067 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000555044 | ENST00000592711 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000334521 | ENST00000446014 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000334521 | ENST00000304283 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| Frame-shift | ENST00000334521 | ENST00000585773 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000334521 | ENST00000450067 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000334521 | ENST00000592711 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| In-frame | ENST00000556797 | ENST00000446014 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| In-frame | ENST00000556797 | ENST00000304283 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| In-frame | ENST00000556797 | ENST00000585773 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000556797 | ENST00000450067 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
| 5CDS-intron | ENST00000556797 | ENST00000592711 | ZNF410 | chr14 | 74364965 | + | ANKS3 | chr16 | 4748063 | - |
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FusionProtFeatures for ZNF410_ANKS3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ZNF410 | ANKS3 |