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Fusion gene ID: 43141

FusionGeneSummary for ZNF264_PIGG

Fusion gene summary

Fusion gene information	Fusion gene name: ZNF264_PIGG
	Fusion gene ID: 43141
		Hgene	Tgene
	Gene symbol	ZNF264	PIGG
	Gene ID	9422	54872
	Gene name	zinc finger protein 264	phosphatidylinositol glycan anchor biosynthesis class G
	Synonyms	-	GPI7\|LAS21\|MRT53\|PRO4405\|RLGS1930
	Cytomap	19q13.43	4p16.3
	Type of gene	protein-coding	protein-coding
	Description	zinc finger protein 264	GPI ethanolamine phosphate transferase 2phosphatidylinositol-glycan biosynthesis class G protein
	Modification date	20180522	20180523
	UniProtAcc	O43296	Q5H8A4
	Ensembl transtripts involved in fusion gene	ENST00000263095, ENST00000600531, ENST00000599653, ENST00000536056,	ENST00000296306, ENST00000310340, ENST00000453061, ENST00000504346, ENST00000383028, ENST00000536264, ENST00000502311, ENST00000503111, ENST00000509768,
Fusion gene scores	* DoF score	1 X 1 X 1=1	3 X 4 X 3=36
	# samples	1	4
	** MAII score	log2(1/1*10)=3.32192809488736	log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: ZNF264 [Title/Abstract] AND PIGG [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	PIGG	GO:0006506	GPI anchor biosynthetic process	15632136

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
TCGA	RV	LUAD	TCGA-50-5930-01A	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000263095	ENST00000296306	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000263095	ENST00000310340	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000263095	ENST00000453061	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000263095	ENST00000504346	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000263095	ENST00000383028	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000263095	ENST00000536264	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000263095	ENST00000502311	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000263095	ENST00000503111	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000263095	ENST00000509768	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000600531	ENST00000296306	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000600531	ENST00000310340	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000600531	ENST00000453061	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000600531	ENST00000504346	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000600531	ENST00000383028	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000600531	ENST00000536264	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000600531	ENST00000502311	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000600531	ENST00000503111	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000600531	ENST00000509768	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000599653	ENST00000296306	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000599653	ENST00000310340	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000599653	ENST00000453061	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000599653	ENST00000504346	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000599653	ENST00000383028	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000599653	ENST00000536264	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000599653	ENST00000502311	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000599653	ENST00000503111	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000599653	ENST00000509768	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000536056	ENST00000296306	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000536056	ENST00000310340	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000536056	ENST00000453061	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000536056	ENST00000504346	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000536056	ENST00000383028	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000536056	ENST00000536264	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000536056	ENST00000502311	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000536056	ENST00000503111	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+
5CDS-intron	ENST00000536056	ENST00000509768	ZNF264	chr19	57705369	+	PIGG	chr4	514845	+

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FusionProtFeatures for ZNF264_PIGG

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
ZNF264 O43296	PIGG Q5H8A4

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Fusion gene ID: 43141

FusionGeneSummary for ZNF264_PIGG

FusionProtFeatures for ZNF264_PIGG