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Fusion gene ID: 43058 |
FusionGeneSummary for ZNF18_TASP1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ZNF18_TASP1 | Fusion gene ID: 43058 | Hgene | Tgene | Gene symbol | ZNF18 | TASP1 | Gene ID | 7566 | 55617 |
| Gene name | zinc finger protein 18 | taspase 1 | |
| Synonyms | HDSG1|KOX11|ZKSCAN6|ZNF535|ZSCAN38|Zfp535 | C20orf13|dJ585I14.2 | |
| Cytomap | 17p12 | 20p12.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | zinc finger protein 18heart development-specific gene 1 proteinzinc finger protein 18 (KOX 11)zinc finger protein 535zinc finger protein with KRAB and SCAN domains 6 | threonine aspartase 1 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P17022 | Q9H6P5 | |
| Ensembl transtripts involved in fusion gene | ENST00000580306, ENST00000322748, ENST00000454073, | ENST00000539805, ENST00000480436, ENST00000337743, ENST00000544472, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 6 X 6 X 4=144 |
| # samples | 1 | 8 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(8/144*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ZNF18 [Title/Abstract] AND TASP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-A2-A0SU-01A | ZNF18 | chr17 | 11887430 | - | TASP1 | chr20 | 13398168 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-3UTR | ENST00000580306 | ENST00000539805 | ZNF18 | chr17 | 11887430 | - | TASP1 | chr20 | 13398168 | - |
| 5CDS-5UTR | ENST00000580306 | ENST00000480436 | ZNF18 | chr17 | 11887430 | - | TASP1 | chr20 | 13398168 | - |
| 5CDS-5UTR | ENST00000580306 | ENST00000337743 | ZNF18 | chr17 | 11887430 | - | TASP1 | chr20 | 13398168 | - |
| 5CDS-intron | ENST00000580306 | ENST00000544472 | ZNF18 | chr17 | 11887430 | - | TASP1 | chr20 | 13398168 | - |
| 5CDS-3UTR | ENST00000322748 | ENST00000539805 | ZNF18 | chr17 | 11887430 | - | TASP1 | chr20 | 13398168 | - |
| 5CDS-5UTR | ENST00000322748 | ENST00000480436 | ZNF18 | chr17 | 11887430 | - | TASP1 | chr20 | 13398168 | - |
| 5CDS-5UTR | ENST00000322748 | ENST00000337743 | ZNF18 | chr17 | 11887430 | - | TASP1 | chr20 | 13398168 | - |
| 5CDS-intron | ENST00000322748 | ENST00000544472 | ZNF18 | chr17 | 11887430 | - | TASP1 | chr20 | 13398168 | - |
| 5CDS-3UTR | ENST00000454073 | ENST00000539805 | ZNF18 | chr17 | 11887430 | - | TASP1 | chr20 | 13398168 | - |
| 5CDS-5UTR | ENST00000454073 | ENST00000480436 | ZNF18 | chr17 | 11887430 | - | TASP1 | chr20 | 13398168 | - |
| 5CDS-5UTR | ENST00000454073 | ENST00000337743 | ZNF18 | chr17 | 11887430 | - | TASP1 | chr20 | 13398168 | - |
| 5CDS-intron | ENST00000454073 | ENST00000544472 | ZNF18 | chr17 | 11887430 | - | TASP1 | chr20 | 13398168 | - |
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FusionProtFeatures for ZNF18_TASP1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ZNF18 | TASP1 |