|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 42989 |
FusionGeneSummary for ZNF106_CNTLN |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ZNF106_CNTLN | Fusion gene ID: 42989 | Hgene | Tgene | Gene symbol | ZNF106 | CNTLN | Gene ID | 64397 | 54875 |
| Gene name | zinc finger protein 106 | centlein | |
| Synonyms | SH3BP3|ZFP106|ZNF474 | C9orf101|C9orf39|bA340N12.1 | |
| Cytomap | 15q15.1 | 9p22.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | zinc finger protein 106SH3-domain binding protein 3zinc finger protein 474 | centleincentlein, centrosomal proteincentrosomal protein | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q9H2Y7 | Q9NXG0 | |
| Ensembl transtripts involved in fusion gene | ENST00000263805, ENST00000565380, ENST00000565611, ENST00000565660, | ENST00000380647, ENST00000262360, ENST00000425824, ENST00000380641, ENST00000484374, | |
| Fusion gene scores | * DoF score | 6 X 7 X 3=126 | 4 X 4 X 4=64 |
| # samples | 9 | 5 | |
| ** MAII score | log2(9/126*10)=-0.485426827170242 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/64*10)=-0.356143810225275 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ZNF106 [Title/Abstract] AND CNTLN [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SKCM | TCGA-BF-AAP2-01A | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000263805 | ENST00000380647 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| In-frame | ENST00000263805 | ENST00000262360 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| In-frame | ENST00000263805 | ENST00000425824 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| 5CDS-intron | ENST00000263805 | ENST00000380641 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| 5CDS-intron | ENST00000263805 | ENST00000484374 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| intron-3CDS | ENST00000565380 | ENST00000380647 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| intron-3CDS | ENST00000565380 | ENST00000262360 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| intron-3CDS | ENST00000565380 | ENST00000425824 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| intron-intron | ENST00000565380 | ENST00000380641 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| intron-intron | ENST00000565380 | ENST00000484374 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| intron-3CDS | ENST00000565611 | ENST00000380647 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| intron-3CDS | ENST00000565611 | ENST00000262360 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| intron-3CDS | ENST00000565611 | ENST00000425824 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| intron-intron | ENST00000565611 | ENST00000380641 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| intron-intron | ENST00000565611 | ENST00000484374 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| intron-3CDS | ENST00000565660 | ENST00000380647 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| intron-3CDS | ENST00000565660 | ENST00000262360 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| intron-3CDS | ENST00000565660 | ENST00000425824 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| intron-intron | ENST00000565660 | ENST00000380641 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
| intron-intron | ENST00000565660 | ENST00000484374 | ZNF106 | chr15 | 42749156 | - | CNTLN | chr9 | 17415786 | + |
Top |
FusionProtFeatures for ZNF106_CNTLN |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ZNF106 | CNTLN |