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Fusion gene ID: 42429 |
FusionGeneSummary for YWHAZ_SCAF11 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: YWHAZ_SCAF11 | Fusion gene ID: 42429 | Hgene | Tgene | Gene symbol | YWHAZ | SCAF11 | Gene ID | 7534 | 9169 |
| Gene name | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta | SR-related CTD associated factor 11 | |
| Synonyms | 14-3-3-zeta|HEL-S-3|HEL-S-93|HEL4|KCIP-1|YWHAD | CASP11|SFRS2IP|SIP1|SRRP129|SRSF2IP | |
| Cytomap | 8q22.3 | 12q12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | 14-3-3 protein zeta/delta14-3-3 delta14-3-3 protein/cytosolic phospholipase A214-3-3 zetaepididymis luminal protein 4epididymis secretory protein Li 3epididymis secretory protein Li 93phospholipase A2protein kinase C inhibitor protein-1tyrosine 3 | protein SCAF11CTD-associated SR protein 11SC35-interacting protein 1SFRS2-interacting proteinSR-related and CTD-associated factor 11SRSF2-interacting proteinrenal carcinoma antigen NY-REN-40serine/arginine-rich splicing factor 2-interacting protein | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | P63104 | Q99590 | |
| Ensembl transtripts involved in fusion gene | ENST00000395957, ENST00000395958, ENST00000457309, ENST00000395956, ENST00000353245, ENST00000522542, ENST00000521309, ENST00000522819, ENST00000395953, ENST00000395948, ENST00000395951, ENST00000419477, ENST00000492736, | ENST00000550629, ENST00000465950, ENST00000369367, ENST00000549162, ENST00000419565, ENST00000395454, ENST00000395453, | |
| Fusion gene scores | * DoF score | 11 X 9 X 5=495 | 3 X 2 X 3=18 |
| # samples | 11 | 3 | |
| ** MAII score | log2(11/495*10)=-2.16992500144231 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: YWHAZ [Title/Abstract] AND SCAF11 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | SCAF11 | GO:0000245 | spliceosomal complex assembly | 9447963 |
| Tgene | SCAF11 | GO:0000375 | RNA splicing, via transesterification reactions | 9447963 |
| Tgene | SCAF11 | GO:0008380 | RNA splicing | 9447963 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-AN-A0FD-01A | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000395957 | ENST00000550629 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395957 | ENST00000465950 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395957 | ENST00000369367 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395957 | ENST00000549162 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395957 | ENST00000419565 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395957 | ENST00000395454 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395957 | ENST00000395453 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395958 | ENST00000550629 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395958 | ENST00000465950 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395958 | ENST00000369367 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395958 | ENST00000549162 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395958 | ENST00000419565 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395958 | ENST00000395454 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395958 | ENST00000395453 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000457309 | ENST00000550629 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000457309 | ENST00000465950 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000457309 | ENST00000369367 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000457309 | ENST00000549162 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000457309 | ENST00000419565 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000457309 | ENST00000395454 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000457309 | ENST00000395453 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395956 | ENST00000550629 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395956 | ENST00000465950 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395956 | ENST00000369367 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395956 | ENST00000549162 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395956 | ENST00000419565 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395956 | ENST00000395454 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395956 | ENST00000395453 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000353245 | ENST00000550629 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000353245 | ENST00000465950 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000353245 | ENST00000369367 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000353245 | ENST00000549162 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000353245 | ENST00000419565 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000353245 | ENST00000395454 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000353245 | ENST00000395453 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000522542 | ENST00000550629 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000522542 | ENST00000465950 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000522542 | ENST00000369367 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000522542 | ENST00000549162 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000522542 | ENST00000419565 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000522542 | ENST00000395454 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000522542 | ENST00000395453 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000521309 | ENST00000550629 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000521309 | ENST00000465950 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000521309 | ENST00000369367 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000521309 | ENST00000549162 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000521309 | ENST00000419565 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000521309 | ENST00000395454 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000521309 | ENST00000395453 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000522819 | ENST00000550629 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000522819 | ENST00000465950 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000522819 | ENST00000369367 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000522819 | ENST00000549162 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000522819 | ENST00000419565 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000522819 | ENST00000395454 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000522819 | ENST00000395453 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395953 | ENST00000550629 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395953 | ENST00000465950 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395953 | ENST00000369367 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395953 | ENST00000549162 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395953 | ENST00000419565 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395953 | ENST00000395454 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395953 | ENST00000395453 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395948 | ENST00000550629 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395948 | ENST00000465950 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395948 | ENST00000369367 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395948 | ENST00000549162 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395948 | ENST00000419565 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395948 | ENST00000395454 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395948 | ENST00000395453 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395951 | ENST00000550629 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395951 | ENST00000465950 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395951 | ENST00000369367 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395951 | ENST00000549162 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395951 | ENST00000419565 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395951 | ENST00000395454 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000395951 | ENST00000395453 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000419477 | ENST00000550629 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000419477 | ENST00000465950 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000419477 | ENST00000369367 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000419477 | ENST00000549162 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000419477 | ENST00000419565 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000419477 | ENST00000395454 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| 5CDS-intron | ENST00000419477 | ENST00000395453 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000492736 | ENST00000550629 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000492736 | ENST00000465950 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000492736 | ENST00000369367 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000492736 | ENST00000549162 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000492736 | ENST00000419565 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000492736 | ENST00000395454 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
| intron-intron | ENST00000492736 | ENST00000395453 | YWHAZ | chr8 | 101960824 | - | SCAF11 | chr12 | 46345510 | - |
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FusionProtFeatures for YWHAZ_SCAF11 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| YWHAZ | SCAF11 |