|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 42346 |
FusionGeneSummary for YLPM1_KHDRBS2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: YLPM1_KHDRBS2 | Fusion gene ID: 42346 | Hgene | Tgene | Gene symbol | YLPM1 | KHDRBS2 | Gene ID | 56252 | 202559 |
| Gene name | YLP motif containing 1 | KH RNA binding domain containing, signal transduction associated 2 | |
| Synonyms | C14orf170|PPP1R169|ZAP113|ZAP3 | SLM-1|SLM1 | |
| Cytomap | 14q24.3 | 6q11.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | YLP motif-containing protein 1nuclear protein ZAP3protein phosphatase 1, regulatory subunit 169 | KH domain-containing, RNA-binding, signal transduction-associated protein 2KH domain containing, RNA binding, signal transduction associated 2Sam68-like mammalian protein 1 | |
| Modification date | 20180519 | 20180522 | |
| UniProtAcc | P49750 | Q5VWX1 | |
| Ensembl transtripts involved in fusion gene | ENST00000238571, ENST00000325680, ENST00000552421, ENST00000546901, | ENST00000281156, | |
| Fusion gene scores | * DoF score | 5 X 8 X 2=80 | 6 X 6 X 6=216 |
| # samples | 9 | 6 | |
| ** MAII score | log2(9/80*10)=0.169925001442312 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(6/216*10)=-1.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: YLPM1 [Title/Abstract] AND KHDRBS2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-SI-A71O-01A | YLPM1 | chr14 | 75291010 | + | KHDRBS2 | chr6 | 62442669 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000238571 | ENST00000281156 | YLPM1 | chr14 | 75291010 | + | KHDRBS2 | chr6 | 62442669 | - |
| Frame-shift | ENST00000325680 | ENST00000281156 | YLPM1 | chr14 | 75291010 | + | KHDRBS2 | chr6 | 62442669 | - |
| Frame-shift | ENST00000552421 | ENST00000281156 | YLPM1 | chr14 | 75291010 | + | KHDRBS2 | chr6 | 62442669 | - |
| 3UTR-3CDS | ENST00000546901 | ENST00000281156 | YLPM1 | chr14 | 75291010 | + | KHDRBS2 | chr6 | 62442669 | - |
Top |
FusionProtFeatures for YLPM1_KHDRBS2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| YLPM1 | KHDRBS2 |