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Fusion gene ID: 42198 |
FusionGeneSummary for XPOT_ARL14EPL |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: XPOT_ARL14EPL | Fusion gene ID: 42198 | Hgene | Tgene | Gene symbol | XPOT | ARL14EPL | Gene ID | 11260 | 644100 |
| Gene name | exportin for tRNA | ADP ribosylation factor like GTPase 14 effector protein like | |
| Synonyms | XPO3 | - | |
| Cytomap | 12q14.2 | 5q23.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | exportin-Texportin(tRNA)exportin, tRNA (nuclear export receptor for tRNAs)tRNA exportin | ARL14 effector protein-likeADP-ribosylation factor-like 14 effector protein-like | |
| Modification date | 20180523 | 20180409 | |
| UniProtAcc | O43592 | P0DKL9 | |
| Ensembl transtripts involved in fusion gene | ENST00000332707, | ENST00000601302, | |
| Fusion gene scores | * DoF score | 6 X 5 X 4=120 | 2 X 2 X 2=8 |
| # samples | 5 | 2 | |
| ** MAII score | log2(5/120*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: XPOT [Title/Abstract] AND ARL14EPL [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | XPOT | GO:0006409 | tRNA export from nucleus | 9660920 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | CN409157 | XPOT | chr12 | 64811874 | + | ARL14EPL | chr5 | 115387639 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000332707 | ENST00000601302 | XPOT | chr12 | 64811874 | + | ARL14EPL | chr5 | 115387639 | - |
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FusionProtFeatures for XPOT_ARL14EPL |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| XPOT | ARL14EPL |