|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 42043 |
FusionGeneSummary for WNK1_PRMT8 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: WNK1_PRMT8 | Fusion gene ID: 42043 | Hgene | Tgene | Gene symbol | WNK1 | PRMT8 | Gene ID | 65125 | 56341 |
| Gene name | WNK lysine deficient protein kinase 1 | protein arginine methyltransferase 8 | |
| Synonyms | HSAN2|HSN2|KDP|PPP1R167|PRKWNK1|PSK|p65 | HRMT1L3|HRMT1L4 | |
| Cytomap | 12p13.33 | 12p13.32 | |
| Type of gene | protein-coding | protein-coding | |
| Description | serine/threonine-protein kinase WNK1WNK lysine deficient protein kinase 1 isoformerythrocyte 65 kDa proteinprostate-derived sterile 20-like kinaseprotein kinase with no lysine 1protein phosphatase 1, regulatory subunit 167serine/threonine-protein ki | protein arginine N-methyltransferase 8HMT1 hnRNP methyltransferase-like 3arginine methyltransferase 8heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4protein arginine N-methyltransferase 4 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9H4A3 | Q9NR22 | |
| Ensembl transtripts involved in fusion gene | ENST00000535572, ENST00000537687, ENST00000315939, ENST00000447667, ENST00000530271, ENST00000540360, ENST00000340908, ENST00000574564, | ENST00000452611, ENST00000382622, ENST00000261252, | |
| Fusion gene scores | * DoF score | 15 X 10 X 10=1500 | 4 X 3 X 3=36 |
| # samples | 19 | 4 | |
| ** MAII score | log2(19/1500*10)=-2.9808911770523 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: WNK1 [Title/Abstract] AND PRMT8 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Kinase involved fusion gene, inframe and retained kinase domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | WNK1 | GO:0006468 | protein phosphorylation | 10660600 |
| Hgene | WNK1 | GO:0010923 | negative regulation of phosphatase activity | 19389623 |
| Hgene | WNK1 | GO:0023016 | signal transduction by trans-phosphorylation | 16669787 |
| Hgene | WNK1 | GO:0035556 | intracellular signal transduction | 10660600 |
| Tgene | PRMT8 | GO:0016571 | histone methylation | 16051612 |
| Tgene | PRMT8 | GO:0018216 | peptidyl-arginine methylation | 16051612|18320585 |
| Tgene | PRMT8 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine | 16051612 |
| Tgene | PRMT8 | GO:0051260 | protein homooligomerization | 26876602 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-BH-A18T-01A | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000535572 | ENST00000452611 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| In-frame | ENST00000535572 | ENST00000382622 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| 5CDS-3UTR | ENST00000535572 | ENST00000261252 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| In-frame | ENST00000537687 | ENST00000452611 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| In-frame | ENST00000537687 | ENST00000382622 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| 5CDS-3UTR | ENST00000537687 | ENST00000261252 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| In-frame | ENST00000315939 | ENST00000452611 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| In-frame | ENST00000315939 | ENST00000382622 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| 5CDS-3UTR | ENST00000315939 | ENST00000261252 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| intron-3CDS | ENST00000447667 | ENST00000452611 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| intron-3CDS | ENST00000447667 | ENST00000382622 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| intron-3UTR | ENST00000447667 | ENST00000261252 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| In-frame | ENST00000530271 | ENST00000452611 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| In-frame | ENST00000530271 | ENST00000382622 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| 5CDS-3UTR | ENST00000530271 | ENST00000261252 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| intron-3CDS | ENST00000540360 | ENST00000452611 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| intron-3CDS | ENST00000540360 | ENST00000382622 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| intron-3UTR | ENST00000540360 | ENST00000261252 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| In-frame | ENST00000340908 | ENST00000452611 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| In-frame | ENST00000340908 | ENST00000382622 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| 5CDS-3UTR | ENST00000340908 | ENST00000261252 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| intron-3CDS | ENST00000574564 | ENST00000452611 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| intron-3CDS | ENST00000574564 | ENST00000382622 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
| intron-3UTR | ENST00000574564 | ENST00000261252 | WNK1 | chr12 | 971436 | + | PRMT8 | chr12 | 3649772 | + |
Top |
FusionProtFeatures for WNK1_PRMT8 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| WNK1 | PRMT8 |
| S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze theformation of omega-N monomethylarginine (MMA) and asymmetricaldimethylarginine (aDMA) in proteins such as NIFK, myelin basicprotein, histone H4, H2A and H2A/H2B dimer (PubMed:16051612,PubMed:17925405, PubMed:26876602, PubMed:26529540). Able tomono- and dimethylate EWS protein; however its precise role towardEWS remains unclear as it still interacts with fully methylatedEWS (PubMed:18320585). {ECO:0000269|PubMed:16051612,ECO:0000269|PubMed:17925405, ECO:0000269|PubMed:18320585,ECO:0000269|PubMed:26529540, ECO:0000269|PubMed:26876602}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | WNK1 | chr12:971436 | chr12:3649772 | ENST00000315939 | + | 8 | 28 | 221_479 | 713 | 2383 | Domain | Protein kinase |
| Hgene | WNK1 | chr12:971436 | chr12:3649772 | ENST00000537687 | + | 8 | 28 | 221_479 | 713 | 2643 | Domain | Protein kinase |
| Hgene | WNK1 | chr12:971436 | chr12:3649772 | ENST00000315939 | + | 8 | 28 | 301_304 | 713 | 2383 | Nucleotide binding | ATP |
| Hgene | WNK1 | chr12:971436 | chr12:3649772 | ENST00000340908 | + | 5 | 25 | 301_304 | 306 | 1976 | Nucleotide binding | ATP |
| Hgene | WNK1 | chr12:971436 | chr12:3649772 | ENST00000537687 | + | 8 | 28 | 301_304 | 713 | 2643 | Nucleotide binding | ATP |
| Hgene | WNK1 | chr12:971436 | chr12:3649772 | ENST00000315939 | + | 8 | 28 | 488_555 | 713 | 2383 | Region | Autoinhibitory domain |
| Hgene | WNK1 | chr12:971436 | chr12:3649772 | ENST00000537687 | + | 8 | 28 | 488_555 | 713 | 2643 | Region | Autoinhibitory domain |
| Tgene | >PRMT8 | chr12:971436 | chr12:3649772 | ENST00000382622 | + | 0 | 10 | 73_394 | 25 | 395 | Domain | SAM-dependent MTase PRMT-type |
| Tgene | >PRMT8 | chr12:971436 | chr12:3649772 | ENST00000452611 | + | 0 | 10 | 73_394 | 16 | 386 | Domain | SAM-dependent MTase PRMT-type |
| Tgene | >PRMT8 | chr12:971436 | chr12:3649772 | ENST00000382622 | + | 0 | 10 | 29_42 | 25 | 395 | Motif | SH3-binding 1 |
| Tgene | >PRMT8 | chr12:971436 | chr12:3649772 | ENST00000382622 | + | 0 | 10 | 53_58 | 25 | 395 | Motif | SH3-binding 2 |
| Tgene | >PRMT8 | chr12:971436 | chr12:3649772 | ENST00000452611 | + | 0 | 10 | 29_42 | 16 | 386 | Motif | SH3-binding 1 |
| Tgene | >PRMT8 | chr12:971436 | chr12:3649772 | ENST00000452611 | + | 0 | 10 | 53_58 | 16 | 386 | Motif | SH3-binding 2 |
| Tgene | >PRMT8 | chr12:971436 | chr12:3649772 | ENST00000382622 | + | 0 | 10 | 119_122 | 25 | 395 | Region | S-adenosyl-L-methionine binding |
| Tgene | >PRMT8 | chr12:971436 | chr12:3649772 | ENST00000452611 | + | 0 | 10 | 119_122 | 16 | 386 | Region | S-adenosyl-L-methionine binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >WNK1 | chr12:971436 | chr12:3649772 | ENST00000340908 | + | 5 | 25 | 221_479 | 306 | 1976 | Domain | Protein kinase |
| Hgene | >WNK1 | chr12:971436 | chr12:3649772 | ENST00000574564 | + | 1 | 1 | 221_479 | -12 | 435 | Domain | Protein kinase |
| Hgene | >WNK1 | chr12:971436 | chr12:3649772 | ENST00000574564 | + | 1 | 1 | 301_304 | -12 | 435 | Nucleotide binding | ATP |
| Hgene | >WNK1 | chr12:971436 | chr12:3649772 | ENST00000340908 | + | 5 | 25 | 488_555 | 306 | 1976 | Region | Autoinhibitory domain |
| Hgene | >WNK1 | chr12:971436 | chr12:3649772 | ENST00000574564 | + | 1 | 1 | 488_555 | -12 | 435 | Region | Autoinhibitory domain |
Top |
FusionGeneSequence for WNK1_PRMT8 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_WNK1_ENST00000535572_chr12_971436_+_PRMT8_ENST00000452611_chr12_3649772_+_1083aa MSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNA TALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPP ARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAE MLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGP TGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIP EVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEM VESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPE EPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVVNSPPSQ PPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGT GILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGG LMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRND YVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYK >In-frame_WNK1_ENST00000535572_chr12_971436_+_PRMT8_ENST00000382622_chr12_3649772_+_1083aa MSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNA TALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPP ARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAE MLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGP TGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIP EVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEM VESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPE EPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVVNSPPSQ PPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGT GILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGG LMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRND YVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYK >In-frame_WNK1_ENST00000537687_chr12_971436_+_PRMT8_ENST00000452611_chr12_3649772_+_1083aa MSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNA TALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPP ARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAE MLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGP TGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIP EVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEM VESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPE EPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVVNSPPSQ PPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGT GILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGG LMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRND YVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYK >In-frame_WNK1_ENST00000537687_chr12_971436_+_PRMT8_ENST00000382622_chr12_3649772_+_1083aa MSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNA TALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPP ARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAE MLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGP TGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIP EVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEM VESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPE EPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVVNSPPSQ PPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGT GILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGG LMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRND YVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYK >In-frame_WNK1_ENST00000315939_chr12_971436_+_PRMT8_ENST00000452611_chr12_3649772_+_1083aa MSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNA TALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPP ARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAE MLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGP TGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIP EVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEM VESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPE EPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVVNSPPSQ PPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGT GILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGG LMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRND YVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYK >In-frame_WNK1_ENST00000315939_chr12_971436_+_PRMT8_ENST00000382622_chr12_3649772_+_1083aa MSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNA TALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPP ARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAE MLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGP TGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIP EVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEM VESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPE EPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVVNSPPSQ PPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGT GILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGG LMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRND YVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYK >In-frame_WNK1_ENST00000530271_chr12_971436_+_PRMT8_ENST00000452611_chr12_3649772_+_1083aa MSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNA TALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPP ARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAE MLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGP TGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIP EVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEM VESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPE EPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVVNSPPSQ PPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGT GILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGG LMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRND YVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYK >In-frame_WNK1_ENST00000530271_chr12_971436_+_PRMT8_ENST00000382622_chr12_3649772_+_1083aa MSGGAAEKQSSTPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAVTGRTEEYRRRRHTMDKDSRGAAATTTTTEHRFFRRSVICDSNA TALELPGLPLSLPQPSIPAAVPQSAPPEPHREETVTATATSQVAQQPPAAAAPGEQAVAGPAPSTVPSSTSKDRPVSQPSLVGSKEEPPP ARSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAE MLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGP TGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIP EVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEM VESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPE EPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVVNSPPSQ PPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGT GILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGG LMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRND YVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYK >In-frame_WNK1_ENST00000340908_chr12_971436_+_PRMT8_ENST00000452611_chr12_3649772_+_676aa MDIKKKDFCSVFVIINSHCCCCPQKDCINEGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEK IAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEES SLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSY GSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVVNSPPSQPPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDS YAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKV EEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPL VDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVR >In-frame_WNK1_ENST00000340908_chr12_971436_+_PRMT8_ENST00000382622_chr12_3649772_+_676aa MDIKKKDFCSVFVIINSHCCCCPQKDCINEGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEETGVRVELAEEDDGEK IAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKKKQEES SLKQQVEQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQQLQYQQPSISVLSDGTVDSGQGSSVFTESRVSSQQTVSY GSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVVNSPPSQPPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDS YAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKV EEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPL VDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVR |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_WNK1_ENST00000535572_chr12_971436_+_PRMT8_ENST00000452611_chr12_3649772_+_3249nt ATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGC TCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACT ATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCC ACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCAC CGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGC CCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCG GCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAG GCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGAC ACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGGATCGAAAATTAACAAAGTCTGAGAGGCAGAGATTTAAAGAAGAAGCTGAA ATGTTAAAAGGTCTTCAGCATCCCAATATTGTTAGATTTTATGATTCCTGGGAATCCACAGTAAAAGGAAAGAAGTGCATTGTTTTGGTG ACTGAACTTATGACGTCTGGAACACTTAAAACGTATCTGAAAAGGTTTAAAGTGATGAAGATCAAAGTTCTAAGAAGCTGGTGCCGTCAG ATCCTTAAAGGTCTTCAGTTTCTTCATACTCGAACTCCACCTATCATTCACCGCGATCTTAAATGTGACAACATCTTTATCACCGGCCCT ACTGGCTCAGTCAAGATTGGAGACCTCGGTCTGGCAACCCTGAAGCGGGCTTCTTTTGCCAAGAGTGTGATAGGTACCCCAGAGTTCATG GCCCCTGAGATGTATGAGGAGAAATATGATGAATCCGTTGACGTTTATGCTTTTGGGATGTGCATGCTTGAGATGGCTACATCTGAATAT CCTTACTCGGAGTGCCAAAATGCTGCACAGATCTACCGTCGCGTGACCAGTGGGGTGAAGCCAGCCAGTTTTGACAAAGTAGCAATTCCT GAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGATATTCCATCAAAGACCTTTTGAACCATGCCTTCTTCCAA GAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAAATAGCCATAAAATTATGGCTACGTATTGAAGATATTAAG AAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGATTTAGAGAGAGATGTCCCAGAAGATGTTGCACAAGAAATG GTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCTATCAAAGACAGAGTATCATTAATTAAGAGGAAACGAGAG CAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGCAGTCTCAAACAGCAGGTAGAACAATCCAGTGCTTCCCAG ACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCTACCACTTCAGCTTCAGTTTCTACACAAGTAGAACCTGAA GAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATATCTGTGTTATCTGATGGGACGGTTGACAGTGGTCAGGGA TCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATATGGTTCCCAACATGAACAGGCACATTCTACAGGCACAGTC CCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTATATCCACCCTCAAGTGTGGTGAACAGCCCCCCCTCCCAG CCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTGTCCACTCAACCCAGCTGCCCAGGACGGGGCAAGATGTCC AAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCCTATGCCCACTTTGGGATCCACGAGGAAATGCTGAAGGAT GAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTGTTCAAGGACAAAGTGGTACTGGATGTGGGGAGTGGTACT GGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGGATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATC ATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTGGAAGAGGTGGAGCTGCCTGTGGAGAAGGTGGACATCATC ATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACGGTGATCTTTGCCAGGGACAAGTGGCTGAAACCTGGAGGG CTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGACAGTACAAGGACTTCAAAATCCACTGGTGGGAGAATGTC TATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTAGTGGACATCGTGGATCCAAAGCAAGTGGTGACCAATGCC TGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCGTTCACATCTGCATTCTGCCTGCAGATACAGCGCAACGAC TACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCACAAGAAAATGGGGTTTTCCACAGCCCCTGATGCTCCCTAC ACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGGAGGGGGGAGGAAATCTACGGGACCATATCCATGAAGCCA AATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAGGGACAGCTGTGTGAAACATCTGTATCTAATGACTACAAA >In-frame_WNK1_ENST00000535572_chr12_971436_+_PRMT8_ENST00000382622_chr12_3649772_+_3249nt ATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGC TCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACT ATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCC ACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCAC CGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGC CCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCG GCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAG GCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGAC ACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGGATCGAAAATTAACAAAGTCTGAGAGGCAGAGATTTAAAGAAGAAGCTGAA ATGTTAAAAGGTCTTCAGCATCCCAATATTGTTAGATTTTATGATTCCTGGGAATCCACAGTAAAAGGAAAGAAGTGCATTGTTTTGGTG ACTGAACTTATGACGTCTGGAACACTTAAAACGTATCTGAAAAGGTTTAAAGTGATGAAGATCAAAGTTCTAAGAAGCTGGTGCCGTCAG ATCCTTAAAGGTCTTCAGTTTCTTCATACTCGAACTCCACCTATCATTCACCGCGATCTTAAATGTGACAACATCTTTATCACCGGCCCT ACTGGCTCAGTCAAGATTGGAGACCTCGGTCTGGCAACCCTGAAGCGGGCTTCTTTTGCCAAGAGTGTGATAGGTACCCCAGAGTTCATG GCCCCTGAGATGTATGAGGAGAAATATGATGAATCCGTTGACGTTTATGCTTTTGGGATGTGCATGCTTGAGATGGCTACATCTGAATAT CCTTACTCGGAGTGCCAAAATGCTGCACAGATCTACCGTCGCGTGACCAGTGGGGTGAAGCCAGCCAGTTTTGACAAAGTAGCAATTCCT GAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGATATTCCATCAAAGACCTTTTGAACCATGCCTTCTTCCAA GAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAAATAGCCATAAAATTATGGCTACGTATTGAAGATATTAAG AAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGATTTAGAGAGAGATGTCCCAGAAGATGTTGCACAAGAAATG GTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCTATCAAAGACAGAGTATCATTAATTAAGAGGAAACGAGAG CAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGCAGTCTCAAACAGCAGGTAGAACAATCCAGTGCTTCCCAG ACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCTACCACTTCAGCTTCAGTTTCTACACAAGTAGAACCTGAA GAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATATCTGTGTTATCTGATGGGACGGTTGACAGTGGTCAGGGA TCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATATGGTTCCCAACATGAACAGGCACATTCTACAGGCACAGTC CCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTATATCCACCCTCAAGTGTGGTGAACAGCCCCCCCTCCCAG CCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTGTCCACTCAACCCAGCTGCCCAGGACGGGGCAAGATGTCC AAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCCTATGCCCACTTTGGGATCCACGAGGAAATGCTGAAGGAT GAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTGTTCAAGGACAAAGTGGTACTGGATGTGGGGAGTGGTACT GGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGGATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATC ATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTGGAAGAGGTGGAGCTGCCTGTGGAGAAGGTGGACATCATC ATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACGGTGATCTTTGCCAGGGACAAGTGGCTGAAACCTGGAGGG CTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGACAGTACAAGGACTTCAAAATCCACTGGTGGGAGAATGTC TATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTAGTGGACATCGTGGATCCAAAGCAAGTGGTGACCAATGCC TGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCGTTCACATCTGCATTCTGCCTGCAGATACAGCGCAACGAC TACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCACAAGAAAATGGGGTTTTCCACAGCCCCTGATGCTCCCTAC ACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGGAGGGGGGAGGAAATCTACGGGACCATATCCATGAAGCCA AATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAGGGACAGCTGTGTGAAACATCTGTATCTAATGACTACAAA >In-frame_WNK1_ENST00000537687_chr12_971436_+_PRMT8_ENST00000452611_chr12_3649772_+_3249nt ATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGC TCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACT ATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCC ACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCAC CGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGC CCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCG GCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAG GCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGAC ACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGGATCGAAAATTAACAAAGTCTGAGAGGCAGAGATTTAAAGAAGAAGCTGAA ATGTTAAAAGGTCTTCAGCATCCCAATATTGTTAGATTTTATGATTCCTGGGAATCCACAGTAAAAGGAAAGAAGTGCATTGTTTTGGTG ACTGAACTTATGACGTCTGGAACACTTAAAACGTATCTGAAAAGGTTTAAAGTGATGAAGATCAAAGTTCTAAGAAGCTGGTGCCGTCAG ATCCTTAAAGGTCTTCAGTTTCTTCATACTCGAACTCCACCTATCATTCACCGCGATCTTAAATGTGACAACATCTTTATCACCGGCCCT ACTGGCTCAGTCAAGATTGGAGACCTCGGTCTGGCAACCCTGAAGCGGGCTTCTTTTGCCAAGAGTGTGATAGGTACCCCAGAGTTCATG GCCCCTGAGATGTATGAGGAGAAATATGATGAATCCGTTGACGTTTATGCTTTTGGGATGTGCATGCTTGAGATGGCTACATCTGAATAT CCTTACTCGGAGTGCCAAAATGCTGCACAGATCTACCGTCGCGTGACCAGTGGGGTGAAGCCAGCCAGTTTTGACAAAGTAGCAATTCCT GAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGATATTCCATCAAAGACCTTTTGAACCATGCCTTCTTCCAA GAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAAATAGCCATAAAATTATGGCTACGTATTGAAGATATTAAG AAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGATTTAGAGAGAGATGTCCCAGAAGATGTTGCACAAGAAATG GTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCTATCAAAGACAGAGTATCATTAATTAAGAGGAAACGAGAG CAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGCAGTCTCAAACAGCAGGTAGAACAATCCAGTGCTTCCCAG ACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCTACCACTTCAGCTTCAGTTTCTACACAAGTAGAACCTGAA GAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATATCTGTGTTATCTGATGGGACGGTTGACAGTGGTCAGGGA TCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATATGGTTCCCAACATGAACAGGCACATTCTACAGGCACAGTC CCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTATATCCACCCTCAAGTGTGGTGAACAGCCCCCCCTCCCAG CCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTGTCCACTCAACCCAGCTGCCCAGGACGGGGCAAGATGTCC AAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCCTATGCCCACTTTGGGATCCACGAGGAAATGCTGAAGGAT GAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTGTTCAAGGACAAAGTGGTACTGGATGTGGGGAGTGGTACT GGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGGATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATC ATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTGGAAGAGGTGGAGCTGCCTGTGGAGAAGGTGGACATCATC ATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACGGTGATCTTTGCCAGGGACAAGTGGCTGAAACCTGGAGGG CTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGACAGTACAAGGACTTCAAAATCCACTGGTGGGAGAATGTC TATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTAGTGGACATCGTGGATCCAAAGCAAGTGGTGACCAATGCC TGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCGTTCACATCTGCATTCTGCCTGCAGATACAGCGCAACGAC TACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCACAAGAAAATGGGGTTTTCCACAGCCCCTGATGCTCCCTAC ACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGGAGGGGGGAGGAAATCTACGGGACCATATCCATGAAGCCA AATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAGGGACAGCTGTGTGAAACATCTGTATCTAATGACTACAAA >In-frame_WNK1_ENST00000537687_chr12_971436_+_PRMT8_ENST00000382622_chr12_3649772_+_3249nt ATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGC TCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACT ATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCC ACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCAC CGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGC CCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCG GCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAG GCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGAC ACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGGATCGAAAATTAACAAAGTCTGAGAGGCAGAGATTTAAAGAAGAAGCTGAA ATGTTAAAAGGTCTTCAGCATCCCAATATTGTTAGATTTTATGATTCCTGGGAATCCACAGTAAAAGGAAAGAAGTGCATTGTTTTGGTG ACTGAACTTATGACGTCTGGAACACTTAAAACGTATCTGAAAAGGTTTAAAGTGATGAAGATCAAAGTTCTAAGAAGCTGGTGCCGTCAG ATCCTTAAAGGTCTTCAGTTTCTTCATACTCGAACTCCACCTATCATTCACCGCGATCTTAAATGTGACAACATCTTTATCACCGGCCCT ACTGGCTCAGTCAAGATTGGAGACCTCGGTCTGGCAACCCTGAAGCGGGCTTCTTTTGCCAAGAGTGTGATAGGTACCCCAGAGTTCATG GCCCCTGAGATGTATGAGGAGAAATATGATGAATCCGTTGACGTTTATGCTTTTGGGATGTGCATGCTTGAGATGGCTACATCTGAATAT CCTTACTCGGAGTGCCAAAATGCTGCACAGATCTACCGTCGCGTGACCAGTGGGGTGAAGCCAGCCAGTTTTGACAAAGTAGCAATTCCT GAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGATATTCCATCAAAGACCTTTTGAACCATGCCTTCTTCCAA GAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAAATAGCCATAAAATTATGGCTACGTATTGAAGATATTAAG AAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGATTTAGAGAGAGATGTCCCAGAAGATGTTGCACAAGAAATG GTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCTATCAAAGACAGAGTATCATTAATTAAGAGGAAACGAGAG CAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGCAGTCTCAAACAGCAGGTAGAACAATCCAGTGCTTCCCAG ACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCTACCACTTCAGCTTCAGTTTCTACACAAGTAGAACCTGAA GAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATATCTGTGTTATCTGATGGGACGGTTGACAGTGGTCAGGGA TCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATATGGTTCCCAACATGAACAGGCACATTCTACAGGCACAGTC CCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTATATCCACCCTCAAGTGTGGTGAACAGCCCCCCCTCCCAG CCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTGTCCACTCAACCCAGCTGCCCAGGACGGGGCAAGATGTCC AAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCCTATGCCCACTTTGGGATCCACGAGGAAATGCTGAAGGAT GAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTGTTCAAGGACAAAGTGGTACTGGATGTGGGGAGTGGTACT GGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGGATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATC ATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTGGAAGAGGTGGAGCTGCCTGTGGAGAAGGTGGACATCATC ATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACGGTGATCTTTGCCAGGGACAAGTGGCTGAAACCTGGAGGG CTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGACAGTACAAGGACTTCAAAATCCACTGGTGGGAGAATGTC TATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTAGTGGACATCGTGGATCCAAAGCAAGTGGTGACCAATGCC TGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCGTTCACATCTGCATTCTGCCTGCAGATACAGCGCAACGAC TACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCACAAGAAAATGGGGTTTTCCACAGCCCCTGATGCTCCCTAC ACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGGAGGGGGGAGGAAATCTACGGGACCATATCCATGAAGCCA AATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAGGGACAGCTGTGTGAAACATCTGTATCTAATGACTACAAA >In-frame_WNK1_ENST00000315939_chr12_971436_+_PRMT8_ENST00000452611_chr12_3649772_+_3249nt ATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGC TCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACT ATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCC ACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCAC CGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGC CCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCG GCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAG GCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGAC ACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGGATCGAAAATTAACAAAGTCTGAGAGGCAGAGATTTAAAGAAGAAGCTGAA ATGTTAAAAGGTCTTCAGCATCCCAATATTGTTAGATTTTATGATTCCTGGGAATCCACAGTAAAAGGAAAGAAGTGCATTGTTTTGGTG ACTGAACTTATGACGTCTGGAACACTTAAAACGTATCTGAAAAGGTTTAAAGTGATGAAGATCAAAGTTCTAAGAAGCTGGTGCCGTCAG ATCCTTAAAGGTCTTCAGTTTCTTCATACTCGAACTCCACCTATCATTCACCGCGATCTTAAATGTGACAACATCTTTATCACCGGCCCT ACTGGCTCAGTCAAGATTGGAGACCTCGGTCTGGCAACCCTGAAGCGGGCTTCTTTTGCCAAGAGTGTGATAGGTACCCCAGAGTTCATG GCCCCTGAGATGTATGAGGAGAAATATGATGAATCCGTTGACGTTTATGCTTTTGGGATGTGCATGCTTGAGATGGCTACATCTGAATAT CCTTACTCGGAGTGCCAAAATGCTGCACAGATCTACCGTCGCGTGACCAGTGGGGTGAAGCCAGCCAGTTTTGACAAAGTAGCAATTCCT GAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGATATTCCATCAAAGACCTTTTGAACCATGCCTTCTTCCAA GAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAAATAGCCATAAAATTATGGCTACGTATTGAAGATATTAAG AAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGATTTAGAGAGAGATGTCCCAGAAGATGTTGCACAAGAAATG GTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCTATCAAAGACAGAGTATCATTAATTAAGAGGAAACGAGAG CAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGCAGTCTCAAACAGCAGGTAGAACAATCCAGTGCTTCCCAG ACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCTACCACTTCAGCTTCAGTTTCTACACAAGTAGAACCTGAA GAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATATCTGTGTTATCTGATGGGACGGTTGACAGTGGTCAGGGA TCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATATGGTTCCCAACATGAACAGGCACATTCTACAGGCACAGTC CCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTATATCCACCCTCAAGTGTGGTGAACAGCCCCCCCTCCCAG CCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTGTCCACTCAACCCAGCTGCCCAGGACGGGGCAAGATGTCC AAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCCTATGCCCACTTTGGGATCCACGAGGAAATGCTGAAGGAT GAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTGTTCAAGGACAAAGTGGTACTGGATGTGGGGAGTGGTACT GGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGGATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATC ATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTGGAAGAGGTGGAGCTGCCTGTGGAGAAGGTGGACATCATC ATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACGGTGATCTTTGCCAGGGACAAGTGGCTGAAACCTGGAGGG CTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGACAGTACAAGGACTTCAAAATCCACTGGTGGGAGAATGTC TATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTAGTGGACATCGTGGATCCAAAGCAAGTGGTGACCAATGCC TGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCGTTCACATCTGCATTCTGCCTGCAGATACAGCGCAACGAC TACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCACAAGAAAATGGGGTTTTCCACAGCCCCTGATGCTCCCTAC ACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGGAGGGGGGAGGAAATCTACGGGACCATATCCATGAAGCCA AATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAGGGACAGCTGTGTGAAACATCTGTATCTAATGACTACAAA >In-frame_WNK1_ENST00000315939_chr12_971436_+_PRMT8_ENST00000382622_chr12_3649772_+_3249nt ATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGC TCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACT ATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCC ACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCAC CGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGC CCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCG GCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAG GCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGAC ACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGGATCGAAAATTAACAAAGTCTGAGAGGCAGAGATTTAAAGAAGAAGCTGAA ATGTTAAAAGGTCTTCAGCATCCCAATATTGTTAGATTTTATGATTCCTGGGAATCCACAGTAAAAGGAAAGAAGTGCATTGTTTTGGTG ACTGAACTTATGACGTCTGGAACACTTAAAACGTATCTGAAAAGGTTTAAAGTGATGAAGATCAAAGTTCTAAGAAGCTGGTGCCGTCAG ATCCTTAAAGGTCTTCAGTTTCTTCATACTCGAACTCCACCTATCATTCACCGCGATCTTAAATGTGACAACATCTTTATCACCGGCCCT ACTGGCTCAGTCAAGATTGGAGACCTCGGTCTGGCAACCCTGAAGCGGGCTTCTTTTGCCAAGAGTGTGATAGGTACCCCAGAGTTCATG GCCCCTGAGATGTATGAGGAGAAATATGATGAATCCGTTGACGTTTATGCTTTTGGGATGTGCATGCTTGAGATGGCTACATCTGAATAT CCTTACTCGGAGTGCCAAAATGCTGCACAGATCTACCGTCGCGTGACCAGTGGGGTGAAGCCAGCCAGTTTTGACAAAGTAGCAATTCCT GAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGATATTCCATCAAAGACCTTTTGAACCATGCCTTCTTCCAA GAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAAATAGCCATAAAATTATGGCTACGTATTGAAGATATTAAG AAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGATTTAGAGAGAGATGTCCCAGAAGATGTTGCACAAGAAATG GTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCTATCAAAGACAGAGTATCATTAATTAAGAGGAAACGAGAG CAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGCAGTCTCAAACAGCAGGTAGAACAATCCAGTGCTTCCCAG ACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCTACCACTTCAGCTTCAGTTTCTACACAAGTAGAACCTGAA GAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATATCTGTGTTATCTGATGGGACGGTTGACAGTGGTCAGGGA TCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATATGGTTCCCAACATGAACAGGCACATTCTACAGGCACAGTC CCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTATATCCACCCTCAAGTGTGGTGAACAGCCCCCCCTCCCAG CCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTGTCCACTCAACCCAGCTGCCCAGGACGGGGCAAGATGTCC AAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCCTATGCCCACTTTGGGATCCACGAGGAAATGCTGAAGGAT GAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTGTTCAAGGACAAAGTGGTACTGGATGTGGGGAGTGGTACT GGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGGATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATC ATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTGGAAGAGGTGGAGCTGCCTGTGGAGAAGGTGGACATCATC ATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACGGTGATCTTTGCCAGGGACAAGTGGCTGAAACCTGGAGGG CTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGACAGTACAAGGACTTCAAAATCCACTGGTGGGAGAATGTC TATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTAGTGGACATCGTGGATCCAAAGCAAGTGGTGACCAATGCC TGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCGTTCACATCTGCATTCTGCCTGCAGATACAGCGCAACGAC TACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCACAAGAAAATGGGGTTTTCCACAGCCCCTGATGCTCCCTAC ACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGGAGGGGGGAGGAAATCTACGGGACCATATCCATGAAGCCA AATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAGGGACAGCTGTGTGAAACATCTGTATCTAATGACTACAAA >In-frame_WNK1_ENST00000530271_chr12_971436_+_PRMT8_ENST00000452611_chr12_3649772_+_3249nt ATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGC TCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACT ATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCC ACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCAC CGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGC CCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCG GCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAG GCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGAC ACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGGATCGAAAATTAACAAAGTCTGAGAGGCAGAGATTTAAAGAAGAAGCTGAA ATGTTAAAAGGTCTTCAGCATCCCAATATTGTTAGATTTTATGATTCCTGGGAATCCACAGTAAAAGGAAAGAAGTGCATTGTTTTGGTG ACTGAACTTATGACGTCTGGAACACTTAAAACGTATCTGAAAAGGTTTAAAGTGATGAAGATCAAAGTTCTAAGAAGCTGGTGCCGTCAG ATCCTTAAAGGTCTTCAGTTTCTTCATACTCGAACTCCACCTATCATTCACCGCGATCTTAAATGTGACAACATCTTTATCACCGGCCCT ACTGGCTCAGTCAAGATTGGAGACCTCGGTCTGGCAACCCTGAAGCGGGCTTCTTTTGCCAAGAGTGTGATAGGTACCCCAGAGTTCATG GCCCCTGAGATGTATGAGGAGAAATATGATGAATCCGTTGACGTTTATGCTTTTGGGATGTGCATGCTTGAGATGGCTACATCTGAATAT CCTTACTCGGAGTGCCAAAATGCTGCACAGATCTACCGTCGCGTGACCAGTGGGGTGAAGCCAGCCAGTTTTGACAAAGTAGCAATTCCT GAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGATATTCCATCAAAGACCTTTTGAACCATGCCTTCTTCCAA GAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAAATAGCCATAAAATTATGGCTACGTATTGAAGATATTAAG AAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGATTTAGAGAGAGATGTCCCAGAAGATGTTGCACAAGAAATG GTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCTATCAAAGACAGAGTATCATTAATTAAGAGGAAACGAGAG CAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGCAGTCTCAAACAGCAGGTAGAACAATCCAGTGCTTCCCAG ACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCTACCACTTCAGCTTCAGTTTCTACACAAGTAGAACCTGAA GAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATATCTGTGTTATCTGATGGGACGGTTGACAGTGGTCAGGGA TCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATATGGTTCCCAACATGAACAGGCACATTCTACAGGCACAGTC CCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTATATCCACCCTCAAGTGTGGTGAACAGCCCCCCCTCCCAG CCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTGTCCACTCAACCCAGCTGCCCAGGACGGGGCAAGATGTCC AAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCCTATGCCCACTTTGGGATCCACGAGGAAATGCTGAAGGAT GAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTGTTCAAGGACAAAGTGGTACTGGATGTGGGGAGTGGTACT GGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGGATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATC ATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTGGAAGAGGTGGAGCTGCCTGTGGAGAAGGTGGACATCATC ATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACGGTGATCTTTGCCAGGGACAAGTGGCTGAAACCTGGAGGG CTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGACAGTACAAGGACTTCAAAATCCACTGGTGGGAGAATGTC TATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTAGTGGACATCGTGGATCCAAAGCAAGTGGTGACCAATGCC TGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCGTTCACATCTGCATTCTGCCTGCAGATACAGCGCAACGAC TACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCACAAGAAAATGGGGTTTTCCACAGCCCCTGATGCTCCCTAC ACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGGAGGGGGGAGGAAATCTACGGGACCATATCCATGAAGCCA AATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAGGGACAGCTGTGTGAAACATCTGTATCTAATGACTACAAA >In-frame_WNK1_ENST00000530271_chr12_971436_+_PRMT8_ENST00000382622_chr12_3649772_+_3249nt ATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGC TCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACT ATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCC ACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCAC CGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGC CCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCG GCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAG GCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGAC ACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGGATCGAAAATTAACAAAGTCTGAGAGGCAGAGATTTAAAGAAGAAGCTGAA ATGTTAAAAGGTCTTCAGCATCCCAATATTGTTAGATTTTATGATTCCTGGGAATCCACAGTAAAAGGAAAGAAGTGCATTGTTTTGGTG ACTGAACTTATGACGTCTGGAACACTTAAAACGTATCTGAAAAGGTTTAAAGTGATGAAGATCAAAGTTCTAAGAAGCTGGTGCCGTCAG ATCCTTAAAGGTCTTCAGTTTCTTCATACTCGAACTCCACCTATCATTCACCGCGATCTTAAATGTGACAACATCTTTATCACCGGCCCT ACTGGCTCAGTCAAGATTGGAGACCTCGGTCTGGCAACCCTGAAGCGGGCTTCTTTTGCCAAGAGTGTGATAGGTACCCCAGAGTTCATG GCCCCTGAGATGTATGAGGAGAAATATGATGAATCCGTTGACGTTTATGCTTTTGGGATGTGCATGCTTGAGATGGCTACATCTGAATAT CCTTACTCGGAGTGCCAAAATGCTGCACAGATCTACCGTCGCGTGACCAGTGGGGTGAAGCCAGCCAGTTTTGACAAAGTAGCAATTCCT GAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGATATTCCATCAAAGACCTTTTGAACCATGCCTTCTTCCAA GAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAAATAGCCATAAAATTATGGCTACGTATTGAAGATATTAAG AAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGATTTAGAGAGAGATGTCCCAGAAGATGTTGCACAAGAAATG GTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCTATCAAAGACAGAGTATCATTAATTAAGAGGAAACGAGAG CAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGCAGTCTCAAACAGCAGGTAGAACAATCCAGTGCTTCCCAG ACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCTACCACTTCAGCTTCAGTTTCTACACAAGTAGAACCTGAA GAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATATCTGTGTTATCTGATGGGACGGTTGACAGTGGTCAGGGA TCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATATGGTTCCCAACATGAACAGGCACATTCTACAGGCACAGTC CCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTATATCCACCCTCAAGTGTGGTGAACAGCCCCCCCTCCCAG CCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTGTCCACTCAACCCAGCTGCCCAGGACGGGGCAAGATGTCC AAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCCTATGCCCACTTTGGGATCCACGAGGAAATGCTGAAGGAT GAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTGTTCAAGGACAAAGTGGTACTGGATGTGGGGAGTGGTACT GGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGGATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATC ATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTGGAAGAGGTGGAGCTGCCTGTGGAGAAGGTGGACATCATC ATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACGGTGATCTTTGCCAGGGACAAGTGGCTGAAACCTGGAGGG CTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGACAGTACAAGGACTTCAAAATCCACTGGTGGGAGAATGTC TATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTAGTGGACATCGTGGATCCAAAGCAAGTGGTGACCAATGCC TGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCGTTCACATCTGCATTCTGCCTGCAGATACAGCGCAACGAC TACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCACAAGAAAATGGGGTTTTCCACAGCCCCTGATGCTCCCTAC ACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGGAGGGGGGAGGAAATCTACGGGACCATATCCATGAAGCCA AATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAGGGACAGCTGTGTGAAACATCTGTATCTAATGACTACAAA >In-frame_WNK1_ENST00000340908_chr12_971436_+_PRMT8_ENST00000452611_chr12_3649772_+_2028nt ATGGATATTAAAAAGAAAGATTTTTGCTCAGTATTTGTCATCATAAATTCTCATTGCTGCTGCTGCCCTCAAAAGGATTGTATAAATGAG GGGGTGAAGCCAGCCAGTTTTGACAAAGTAGCAATTCCTGAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGA TATTCCATCAAAGACCTTTTGAACCATGCCTTCTTCCAAGAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAA ATAGCCATAAAATTATGGCTACGTATTGAAGATATTAAGAAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGAT TTAGAGAGAGATGTCCCAGAAGATGTTGCACAAGAAATGGTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCT ATCAAAGACAGAGTATCATTAATTAAGAGGAAACGAGAGCAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGC AGTCTCAAACAGCAGGTAGAACAATCCAGTGCTTCCCAGACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCT ACCACTTCAGCTTCAGTTTCTACACAAGTAGAACCTGAAGAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATA TCTGTGTTATCTGATGGGACGGTTGACAGTGGTCAGGGATCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATAT GGTTCCCAACATGAACAGGCACATTCTACAGGCACAGTCCCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTA TATCCACCCTCAAGTGTGGTGAACAGCCCCCCCTCCCAGCCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTG TCCACTCAACCCAGCTGCCCAGGACGGGGCAAGATGTCCAAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCC TATGCCCACTTTGGGATCCACGAGGAAATGCTGAAGGATGAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTG TTCAAGGACAAAGTGGTACTGGATGTGGGGAGTGGTACTGGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGG ATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATCATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTG GAAGAGGTGGAGCTGCCTGTGGAGAAGGTGGACATCATCATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACG GTGATCTTTGCCAGGGACAAGTGGCTGAAACCTGGAGGGCTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGA CAGTACAAGGACTTCAAAATCCACTGGTGGGAGAATGTCTATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTA GTGGACATCGTGGATCCAAAGCAAGTGGTGACCAATGCCTGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCG TTCACATCTGCATTCTGCCTGCAGATACAGCGCAACGACTACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCAC AAGAAAATGGGGTTTTCCACAGCCCCTGATGCTCCCTACACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGG AGGGGGGAGGAAATCTACGGGACCATATCCATGAAGCCAAATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAG >In-frame_WNK1_ENST00000340908_chr12_971436_+_PRMT8_ENST00000382622_chr12_3649772_+_2028nt ATGGATATTAAAAAGAAAGATTTTTGCTCAGTATTTGTCATCATAAATTCTCATTGCTGCTGCTGCCCTCAAAAGGATTGTATAAATGAG GGGGTGAAGCCAGCCAGTTTTGACAAAGTAGCAATTCCTGAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGA TATTCCATCAAAGACCTTTTGAACCATGCCTTCTTCCAAGAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAA ATAGCCATAAAATTATGGCTACGTATTGAAGATATTAAGAAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGAT TTAGAGAGAGATGTCCCAGAAGATGTTGCACAAGAAATGGTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCT ATCAAAGACAGAGTATCATTAATTAAGAGGAAACGAGAGCAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGC AGTCTCAAACAGCAGGTAGAACAATCCAGTGCTTCCCAGACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCT ACCACTTCAGCTTCAGTTTCTACACAAGTAGAACCTGAAGAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATA TCTGTGTTATCTGATGGGACGGTTGACAGTGGTCAGGGATCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATAT GGTTCCCAACATGAACAGGCACATTCTACAGGCACAGTCCCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTA TATCCACCCTCAAGTGTGGTGAACAGCCCCCCCTCCCAGCCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTG TCCACTCAACCCAGCTGCCCAGGACGGGGCAAGATGTCCAAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCC TATGCCCACTTTGGGATCCACGAGGAAATGCTGAAGGATGAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTG TTCAAGGACAAAGTGGTACTGGATGTGGGGAGTGGTACTGGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGG ATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATCATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTG GAAGAGGTGGAGCTGCCTGTGGAGAAGGTGGACATCATCATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACG GTGATCTTTGCCAGGGACAAGTGGCTGAAACCTGGAGGGCTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGA CAGTACAAGGACTTCAAAATCCACTGGTGGGAGAATGTCTATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTA GTGGACATCGTGGATCCAAAGCAAGTGGTGACCAATGCCTGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCG TTCACATCTGCATTCTGCCTGCAGATACAGCGCAACGACTACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCAC AAGAAAATGGGGTTTTCCACAGCCCCTGATGCTCCCTACACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGG AGGGGGGAGGAAATCTACGGGACCATATCCATGAAGCCAAATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_WNK1_ENST00000535572_chr12_971436_+_PRMT8_ENST00000452611_chr12_3649772_+_4222nt ATTTAGCGCGGAGAGTTTCCCGGGTGGACGCGGCTCCTCTCTCGGCCACTCCGCACCCCCATCTTCGGTGACAGAAGGCGCCTGGTGGGG GTGGCTGCTCTTTTCTCTCCCTGTTCCCCCTCACCCAGTCCTCTAGGTCTCCTCTCCTCTTGCCTCAGAGAAGCAGCGGAGCTCGGGCCC CGCGGTGAGCGGCCCTCCCCTCCCCGCCGTTCCCTCCTCCGTCAGCCCCCGGCACCGGCCCGGGAGGAGACGGGTTTGCCAGGCCTGGGG CGGGCGGGGAGGCCTCGGGGAAGGGGGGGCCCGCTCCTCAGGCGCCGAGGCTCCGAGGCTCCGGCCCTTCGCCTCTGGGCGATGGGCGAC CTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGACCGGGAGCCGGGCCGCGGCCTTCCCTCGCCC GCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGTCCCGTGCTCGCGGTGCCGCCGCCCTCTGGG CCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTCGACTCGGTGCCGGCCCCTGGCCCTCCCCTC ATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATGCGGACCGTGCGGCGCTAACCCCCGTGGCTC AGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGCCCCCGCCGCAGCTGGGCCCAGCGGTCCGCC TGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCGCCCGGCCGCGGTTCCCTGCAGACCTCTGCG CGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTCCAGCGAACCGACCATGTCTGGCGGCGCCGC AGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGCTCCGATTCCTCCGTGGG GGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACTATGGACAAGGACAGCCG TGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCCACTGCACTGGAGCTTCC CGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCACCGGGAAGAGACCGTGAC CGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGCCCTGCCCCCTCGACTGT CCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCGGCGAGAAGTGGCAGCGG CGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAGGCCGTGGGAATGTCTAA CGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGACACTGAAACCACCGTGGA AGTCGCCTGGTGTGAACTGCAGGATCGAAAATTAACAAAGTCTGAGAGGCAGAGATTTAAAGAAGAAGCTGAAATGTTAAAAGGTCTTCA GCATCCCAATATTGTTAGATTTTATGATTCCTGGGAATCCACAGTAAAAGGAAAGAAGTGCATTGTTTTGGTGACTGAACTTATGACGTC TGGAACACTTAAAACGTATCTGAAAAGGTTTAAAGTGATGAAGATCAAAGTTCTAAGAAGCTGGTGCCGTCAGATCCTTAAAGGTCTTCA GTTTCTTCATACTCGAACTCCACCTATCATTCACCGCGATCTTAAATGTGACAACATCTTTATCACCGGCCCTACTGGCTCAGTCAAGAT TGGAGACCTCGGTCTGGCAACCCTGAAGCGGGCTTCTTTTGCCAAGAGTGTGATAGGTACCCCAGAGTTCATGGCCCCTGAGATGTATGA GGAGAAATATGATGAATCCGTTGACGTTTATGCTTTTGGGATGTGCATGCTTGAGATGGCTACATCTGAATATCCTTACTCGGAGTGCCA AAATGCTGCACAGATCTACCGTCGCGTGACCAGTGGGGTGAAGCCAGCCAGTTTTGACAAAGTAGCAATTCCTGAAGTGAAGGAAATTAT TGAAGGATGCATACGACAAAACAAAGATGAAAGATATTCCATCAAAGACCTTTTGAACCATGCCTTCTTCCAAGAGGAAACAGGAGTACG GGTAGAATTAGCAGAAGAAGATGATGGAGAAAAAATAGCCATAAAATTATGGCTACGTATTGAAGATATTAAGAAATTAAAGGGAAAATA CAAAGATAATGAAGCTATTGAGTTTTCTTTTGATTTAGAGAGAGATGTCCCAGAAGATGTTGCACAAGAAATGGTAGAGTCTGGGTATGT CTGTGAAGGTGATCACAAGACCATGGCTAAAGCTATCAAAGACAGAGTATCATTAATTAAGAGGAAACGAGAGCAGCGGCAGTTGGTACG GGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGCAGTCTCAAACAGCAGGTAGAACAATCCAGTGCTTCCCAGACAGGAATCAAGCAGCT CCCTTCTGCTAGCACCGGCATACCTACTGCTTCTACCACTTCAGCTTCAGTTTCTACACAAGTAGAACCTGAAGAACCTGAGGCAGATCA ACATCAACAACTACAGTACCAGCAACCCAGTATATCTGTGTTATCTGATGGGACGGTTGACAGTGGTCAGGGATCCTCTGTCTTCACAGA ATCTCGAGTGAGCAGCCAACAGACAGTTTCATATGGTTCCCAACATGAACAGGCACATTCTACAGGCACAGTCCCAGGGCATATACCTTC TACTGTCCAAGCACAGTCTCAGCCCCATGGGGTATATCCACCCTCAAGTGTGGTGAACAGCCCCCCCTCCCAGCCCCCCCAGCCCGTCGT CCCTGCTAAGCCCGTGCAATGCGTCCATCATGTGTCCACTCAACCCAGCTGCCCAGGACGGGGCAAGATGTCCAAGCTGCTGAACCCAGA GGAGATGACCTCGAGAGATTATTACTTCGACTCCTATGCCCACTTTGGGATCCACGAGGAAATGCTGAAGGATGAGGTGCGGACTCTCAC TTACCGGAACTCCATGTACCACAACAAGCACGTGTTCAAGGACAAAGTGGTACTGGATGTGGGGAGTGGTACTGGGATCCTTTCCATGTT CGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGGATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATCATTAAGGCCAACCACTT GGACAACATCATCACCATATTTAAGGGTAAAGTGGAAGAGGTGGAGCTGCCTGTGGAGAAGGTGGACATCATCATCAGCGAGTGGATGGG CTACTGTCTGTTCTATGAGTCCATGCTCAACACGGTGATCTTTGCCAGGGACAAGTGGCTGAAACCTGGAGGGCTTATGTTTCCAGACCG GGCAGCTTTGTACGTGGTAGCGATTGAAGACAGACAGTACAAGGACTTCAAAATCCACTGGTGGGAGAATGTCTATGGCTTTGACATGAC CTGCATCCGGGACGTGGCCATGAAGGAGCCTCTAGTGGACATCGTGGATCCAAAGCAAGTGGTGACCAATGCCTGTTTGATAAAGGAGGT GGACATTTACACAGTGAAGACGGAAGAGCTATCGTTCACATCTGCATTCTGCCTGCAGATACAGCGCAACGACTACGTCCACGCCCTGGT CACCTATTTTAATATTGAATTTACCAAGTGCCACAAGAAAATGGGGTTTTCCACAGCCCCTGATGCTCCCTACACCCACTGGAAGCAGAC CGTCTTCTACTTGGAAGATTACCTCACTGTCCGGAGGGGGGAGGAAATCTACGGGACCATATCCATGAAGCCAAATGCCAAAAATGTGCG >In-frame_WNK1_ENST00000535572_chr12_971436_+_PRMT8_ENST00000382622_chr12_3649772_+_5013nt ATTTAGCGCGGAGAGTTTCCCGGGTGGACGCGGCTCCTCTCTCGGCCACTCCGCACCCCCATCTTCGGTGACAGAAGGCGCCTGGTGGGG GTGGCTGCTCTTTTCTCTCCCTGTTCCCCCTCACCCAGTCCTCTAGGTCTCCTCTCCTCTTGCCTCAGAGAAGCAGCGGAGCTCGGGCCC CGCGGTGAGCGGCCCTCCCCTCCCCGCCGTTCCCTCCTCCGTCAGCCCCCGGCACCGGCCCGGGAGGAGACGGGTTTGCCAGGCCTGGGG CGGGCGGGGAGGCCTCGGGGAAGGGGGGGCCCGCTCCTCAGGCGCCGAGGCTCCGAGGCTCCGGCCCTTCGCCTCTGGGCGATGGGCGAC CTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGACCGGGAGCCGGGCCGCGGCCTTCCCTCGCCC GCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGTCCCGTGCTCGCGGTGCCGCCGCCCTCTGGG CCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTCGACTCGGTGCCGGCCCCTGGCCCTCCCCTC ATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATGCGGACCGTGCGGCGCTAACCCCCGTGGCTC AGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGCCCCCGCCGCAGCTGGGCCCAGCGGTCCGCC TGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCGCCCGGCCGCGGTTCCCTGCAGACCTCTGCG CGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTCCAGCGAACCGACCATGTCTGGCGGCGCCGC AGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGCTCCGATTCCTCCGTGGG GGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACTATGGACAAGGACAGCCG TGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCCACTGCACTGGAGCTTCC CGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCACCGGGAAGAGACCGTGAC CGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGCCCTGCCCCCTCGACTGT CCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCGGCGAGAAGTGGCAGCGG CGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAGGCCGTGGGAATGTCTAA CGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGACACTGAAACCACCGTGGA AGTCGCCTGGTGTGAACTGCAGGATCGAAAATTAACAAAGTCTGAGAGGCAGAGATTTAAAGAAGAAGCTGAAATGTTAAAAGGTCTTCA GCATCCCAATATTGTTAGATTTTATGATTCCTGGGAATCCACAGTAAAAGGAAAGAAGTGCATTGTTTTGGTGACTGAACTTATGACGTC TGGAACACTTAAAACGTATCTGAAAAGGTTTAAAGTGATGAAGATCAAAGTTCTAAGAAGCTGGTGCCGTCAGATCCTTAAAGGTCTTCA GTTTCTTCATACTCGAACTCCACCTATCATTCACCGCGATCTTAAATGTGACAACATCTTTATCACCGGCCCTACTGGCTCAGTCAAGAT TGGAGACCTCGGTCTGGCAACCCTGAAGCGGGCTTCTTTTGCCAAGAGTGTGATAGGTACCCCAGAGTTCATGGCCCCTGAGATGTATGA GGAGAAATATGATGAATCCGTTGACGTTTATGCTTTTGGGATGTGCATGCTTGAGATGGCTACATCTGAATATCCTTACTCGGAGTGCCA AAATGCTGCACAGATCTACCGTCGCGTGACCAGTGGGGTGAAGCCAGCCAGTTTTGACAAAGTAGCAATTCCTGAAGTGAAGGAAATTAT TGAAGGATGCATACGACAAAACAAAGATGAAAGATATTCCATCAAAGACCTTTTGAACCATGCCTTCTTCCAAGAGGAAACAGGAGTACG GGTAGAATTAGCAGAAGAAGATGATGGAGAAAAAATAGCCATAAAATTATGGCTACGTATTGAAGATATTAAGAAATTAAAGGGAAAATA CAAAGATAATGAAGCTATTGAGTTTTCTTTTGATTTAGAGAGAGATGTCCCAGAAGATGTTGCACAAGAAATGGTAGAGTCTGGGTATGT CTGTGAAGGTGATCACAAGACCATGGCTAAAGCTATCAAAGACAGAGTATCATTAATTAAGAGGAAACGAGAGCAGCGGCAGTTGGTACG GGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGCAGTCTCAAACAGCAGGTAGAACAATCCAGTGCTTCCCAGACAGGAATCAAGCAGCT CCCTTCTGCTAGCACCGGCATACCTACTGCTTCTACCACTTCAGCTTCAGTTTCTACACAAGTAGAACCTGAAGAACCTGAGGCAGATCA ACATCAACAACTACAGTACCAGCAACCCAGTATATCTGTGTTATCTGATGGGACGGTTGACAGTGGTCAGGGATCCTCTGTCTTCACAGA ATCTCGAGTGAGCAGCCAACAGACAGTTTCATATGGTTCCCAACATGAACAGGCACATTCTACAGGCACAGTCCCAGGGCATATACCTTC TACTGTCCAAGCACAGTCTCAGCCCCATGGGGTATATCCACCCTCAAGTGTGGTGAACAGCCCCCCCTCCCAGCCCCCCCAGCCCGTCGT CCCTGCTAAGCCCGTGCAATGCGTCCATCATGTGTCCACTCAACCCAGCTGCCCAGGACGGGGCAAGATGTCCAAGCTGCTGAACCCAGA GGAGATGACCTCGAGAGATTATTACTTCGACTCCTATGCCCACTTTGGGATCCACGAGGAAATGCTGAAGGATGAGGTGCGGACTCTCAC TTACCGGAACTCCATGTACCACAACAAGCACGTGTTCAAGGACAAAGTGGTACTGGATGTGGGGAGTGGTACTGGGATCCTTTCCATGTT CGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGGATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATCATTAAGGCCAACCACTT GGACAACATCATCACCATATTTAAGGGTAAAGTGGAAGAGGTGGAGCTGCCTGTGGAGAAGGTGGACATCATCATCAGCGAGTGGATGGG CTACTGTCTGTTCTATGAGTCCATGCTCAACACGGTGATCTTTGCCAGGGACAAGTGGCTGAAACCTGGAGGGCTTATGTTTCCAGACCG GGCAGCTTTGTACGTGGTAGCGATTGAAGACAGACAGTACAAGGACTTCAAAATCCACTGGTGGGAGAATGTCTATGGCTTTGACATGAC CTGCATCCGGGACGTGGCCATGAAGGAGCCTCTAGTGGACATCGTGGATCCAAAGCAAGTGGTGACCAATGCCTGTTTGATAAAGGAGGT GGACATTTACACAGTGAAGACGGAAGAGCTATCGTTCACATCTGCATTCTGCCTGCAGATACAGCGCAACGACTACGTCCACGCCCTGGT CACCTATTTTAATATTGAATTTACCAAGTGCCACAAGAAAATGGGGTTTTCCACAGCCCCTGATGCTCCCTACACCCACTGGAAGCAGAC CGTCTTCTACTTGGAAGATTACCTCACTGTCCGGAGGGGGGAGGAAATCTACGGGACCATATCCATGAAGCCAAATGCCAAAAATGTGCG AGACCTCGATTTCACAGTAGACTTGGATTTTAAGGGACAGCTGTGTGAAACATCTGTATCTAATGACTACAAAATGCGTTAGCACACGTG GGAAGCTGCAGAGAGCAACGAGAAAAGGAACTCTCACCTCGATCTGCCGTGCCGTCCCAAAGAATACCGTTTGCAGGACTACACACTTGA AAACCAGAGTTTTCAACTCTGCCTTGAAGATTGGTGAACTCCCCAGGGCTCCCGTGGGCTCTGCCACTGGACAGAAGGCCTCCAGCTCCT CCGCTCTGCCCTGGTAGCCCTTCACGAAGGCTTTGTGTTGCCAACAAAGAGCGACCTGGCGTGCTGTGGCTGGGCCCCGAGGGTGGAAAC GTATTCGCGTCTCCCCGTCTCCTCCTTAACTGTGACTCTCCGGGTCTTCTGAGTTTTGCATGCTGCGGGTGTCTAGGACAGATTGCTTCC ACTAGAACCTGGAGACATAGCATCTTTGATAGCATAAGCCAGATTATCTGTGTGTGCGGTGGTGTGCGTGTGCGTGCATGTGTGAATGTG AGCAGCATAGTTGATATTTACCCACAAACACCTGTATATGCGTGCATATACAACCAAGTGGGTAGACCTAGGTGTTCTCTCAGAGGGGTG TGTGTGTGTGTGCGTGCGCGTGTGCCTAGAATATATATTACTCTCAGAGGAGATTCTGTTGCTTTTGAATAGGAATTTGTTTTGTGATTA GTTCGCCCCTTCCCCACCCCTTACCAGATGTTAAGCAGCTATGAAACATTCTCTGTACTAGTTCTGGTCTCCTTTTGACTGGACTGTGGC >In-frame_WNK1_ENST00000537687_chr12_971436_+_PRMT8_ENST00000452611_chr12_3649772_+_3892nt CCGGCCCTTCGCCTCTGGGCGATGGGCGACCTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGAC CGGGAGCCGGGCCGCGGCCTTCCCTCGCCCGCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGT CCCGTGCTCGCGGTGCCGCCGCCCTCTGGGCCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTC GACTCGGTGCCGGCCCCTGGCCCTCCCCTCATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATG CGGACCGTGCGGCGCTAACCCCCGTGGCTCAGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGC CCCCGCCGCAGCTGGGCCCAGCGGTCCGCCTGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCG CCCGGCCGCGGTTCCCTGCAGACCTCTGCGCGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTC CAGCGAACCGACCATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAA GAATGGCTCCAGCTCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCG CCGCCGCCACACTATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTG TGACTCCAATGCCACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCC ACCGGAGCCCCACCGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACA GGCCGTCGCGGGCCCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGA GGAGCCGCCGCCGGCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGA GCTGGAGACCAAGGCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTA CAAAGGTCTGGACACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGGATCGAAAATTAACAAAGTCTGAGAGGCAGAGATTTAA AGAAGAAGCTGAAATGTTAAAAGGTCTTCAGCATCCCAATATTGTTAGATTTTATGATTCCTGGGAATCCACAGTAAAAGGAAAGAAGTG CATTGTTTTGGTGACTGAACTTATGACGTCTGGAACACTTAAAACGTATCTGAAAAGGTTTAAAGTGATGAAGATCAAAGTTCTAAGAAG CTGGTGCCGTCAGATCCTTAAAGGTCTTCAGTTTCTTCATACTCGAACTCCACCTATCATTCACCGCGATCTTAAATGTGACAACATCTT TATCACCGGCCCTACTGGCTCAGTCAAGATTGGAGACCTCGGTCTGGCAACCCTGAAGCGGGCTTCTTTTGCCAAGAGTGTGATAGGTAC CCCAGAGTTCATGGCCCCTGAGATGTATGAGGAGAAATATGATGAATCCGTTGACGTTTATGCTTTTGGGATGTGCATGCTTGAGATGGC TACATCTGAATATCCTTACTCGGAGTGCCAAAATGCTGCACAGATCTACCGTCGCGTGACCAGTGGGGTGAAGCCAGCCAGTTTTGACAA AGTAGCAATTCCTGAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGATATTCCATCAAAGACCTTTTGAACCA TGCCTTCTTCCAAGAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAAATAGCCATAAAATTATGGCTACGTAT TGAAGATATTAAGAAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGATTTAGAGAGAGATGTCCCAGAAGATGT TGCACAAGAAATGGTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCTATCAAAGACAGAGTATCATTAATTAA GAGGAAACGAGAGCAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGCAGTCTCAAACAGCAGGTAGAACAATC CAGTGCTTCCCAGACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCTACCACTTCAGCTTCAGTTTCTACACA AGTAGAACCTGAAGAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATATCTGTGTTATCTGATGGGACGGTTGA CAGTGGTCAGGGATCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATATGGTTCCCAACATGAACAGGCACATTC TACAGGCACAGTCCCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTATATCCACCCTCAAGTGTGGTGAACAG CCCCCCCTCCCAGCCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTGTCCACTCAACCCAGCTGCCCAGGACG GGGCAAGATGTCCAAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCCTATGCCCACTTTGGGATCCACGAGGA AATGCTGAAGGATGAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTGTTCAAGGACAAAGTGGTACTGGATGT GGGGAGTGGTACTGGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGGATCGAATGCTCCAGTATTTCTGACTA CTCAGAGAAGATCATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTGGAAGAGGTGGAGCTGCCTGTGGAGAA GGTGGACATCATCATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACGGTGATCTTTGCCAGGGACAAGTGGCT GAAACCTGGAGGGCTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGACAGTACAAGGACTTCAAAATCCACTG GTGGGAGAATGTCTATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTAGTGGACATCGTGGATCCAAAGCAAGT GGTGACCAATGCCTGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCGTTCACATCTGCATTCTGCCTGCAGAT ACAGCGCAACGACTACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCACAAGAAAATGGGGTTTTCCACAGCCCC TGATGCTCCCTACACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGGAGGGGGGAGGAAATCTACGGGACCAT ATCCATGAAGCCAAATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAGGGACAGCTGTGTGAAACATCTGTATC >In-frame_WNK1_ENST00000537687_chr12_971436_+_PRMT8_ENST00000382622_chr12_3649772_+_4683nt CCGGCCCTTCGCCTCTGGGCGATGGGCGACCTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGAC CGGGAGCCGGGCCGCGGCCTTCCCTCGCCCGCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGT CCCGTGCTCGCGGTGCCGCCGCCCTCTGGGCCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTC GACTCGGTGCCGGCCCCTGGCCCTCCCCTCATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATG CGGACCGTGCGGCGCTAACCCCCGTGGCTCAGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGC CCCCGCCGCAGCTGGGCCCAGCGGTCCGCCTGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCG CCCGGCCGCGGTTCCCTGCAGACCTCTGCGCGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTC CAGCGAACCGACCATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAA GAATGGCTCCAGCTCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCG CCGCCGCCACACTATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTG TGACTCCAATGCCACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCC ACCGGAGCCCCACCGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACA GGCCGTCGCGGGCCCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGA GGAGCCGCCGCCGGCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGA GCTGGAGACCAAGGCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTA CAAAGGTCTGGACACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGGATCGAAAATTAACAAAGTCTGAGAGGCAGAGATTTAA AGAAGAAGCTGAAATGTTAAAAGGTCTTCAGCATCCCAATATTGTTAGATTTTATGATTCCTGGGAATCCACAGTAAAAGGAAAGAAGTG CATTGTTTTGGTGACTGAACTTATGACGTCTGGAACACTTAAAACGTATCTGAAAAGGTTTAAAGTGATGAAGATCAAAGTTCTAAGAAG CTGGTGCCGTCAGATCCTTAAAGGTCTTCAGTTTCTTCATACTCGAACTCCACCTATCATTCACCGCGATCTTAAATGTGACAACATCTT TATCACCGGCCCTACTGGCTCAGTCAAGATTGGAGACCTCGGTCTGGCAACCCTGAAGCGGGCTTCTTTTGCCAAGAGTGTGATAGGTAC CCCAGAGTTCATGGCCCCTGAGATGTATGAGGAGAAATATGATGAATCCGTTGACGTTTATGCTTTTGGGATGTGCATGCTTGAGATGGC TACATCTGAATATCCTTACTCGGAGTGCCAAAATGCTGCACAGATCTACCGTCGCGTGACCAGTGGGGTGAAGCCAGCCAGTTTTGACAA AGTAGCAATTCCTGAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGATATTCCATCAAAGACCTTTTGAACCA TGCCTTCTTCCAAGAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAAATAGCCATAAAATTATGGCTACGTAT TGAAGATATTAAGAAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGATTTAGAGAGAGATGTCCCAGAAGATGT TGCACAAGAAATGGTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCTATCAAAGACAGAGTATCATTAATTAA GAGGAAACGAGAGCAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGCAGTCTCAAACAGCAGGTAGAACAATC CAGTGCTTCCCAGACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCTACCACTTCAGCTTCAGTTTCTACACA AGTAGAACCTGAAGAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATATCTGTGTTATCTGATGGGACGGTTGA CAGTGGTCAGGGATCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATATGGTTCCCAACATGAACAGGCACATTC TACAGGCACAGTCCCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTATATCCACCCTCAAGTGTGGTGAACAG CCCCCCCTCCCAGCCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTGTCCACTCAACCCAGCTGCCCAGGACG GGGCAAGATGTCCAAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCCTATGCCCACTTTGGGATCCACGAGGA AATGCTGAAGGATGAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTGTTCAAGGACAAAGTGGTACTGGATGT GGGGAGTGGTACTGGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGGATCGAATGCTCCAGTATTTCTGACTA CTCAGAGAAGATCATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTGGAAGAGGTGGAGCTGCCTGTGGAGAA GGTGGACATCATCATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACGGTGATCTTTGCCAGGGACAAGTGGCT GAAACCTGGAGGGCTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGACAGTACAAGGACTTCAAAATCCACTG GTGGGAGAATGTCTATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTAGTGGACATCGTGGATCCAAAGCAAGT GGTGACCAATGCCTGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCGTTCACATCTGCATTCTGCCTGCAGAT ACAGCGCAACGACTACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCACAAGAAAATGGGGTTTTCCACAGCCCC TGATGCTCCCTACACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGGAGGGGGGAGGAAATCTACGGGACCAT ATCCATGAAGCCAAATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAGGGACAGCTGTGTGAAACATCTGTATC TAATGACTACAAAATGCGTTAGCACACGTGGGAAGCTGCAGAGAGCAACGAGAAAAGGAACTCTCACCTCGATCTGCCGTGCCGTCCCAA AGAATACCGTTTGCAGGACTACACACTTGAAAACCAGAGTTTTCAACTCTGCCTTGAAGATTGGTGAACTCCCCAGGGCTCCCGTGGGCT CTGCCACTGGACAGAAGGCCTCCAGCTCCTCCGCTCTGCCCTGGTAGCCCTTCACGAAGGCTTTGTGTTGCCAACAAAGAGCGACCTGGC GTGCTGTGGCTGGGCCCCGAGGGTGGAAACGTATTCGCGTCTCCCCGTCTCCTCCTTAACTGTGACTCTCCGGGTCTTCTGAGTTTTGCA TGCTGCGGGTGTCTAGGACAGATTGCTTCCACTAGAACCTGGAGACATAGCATCTTTGATAGCATAAGCCAGATTATCTGTGTGTGCGGT GGTGTGCGTGTGCGTGCATGTGTGAATGTGAGCAGCATAGTTGATATTTACCCACAAACACCTGTATATGCGTGCATATACAACCAAGTG GGTAGACCTAGGTGTTCTCTCAGAGGGGTGTGTGTGTGTGTGCGTGCGCGTGTGCCTAGAATATATATTACTCTCAGAGGAGATTCTGTT GCTTTTGAATAGGAATTTGTTTTGTGATTAGTTCGCCCCTTCCCCACCCCTTACCAGATGTTAAGCAGCTATGAAACATTCTCTGTACTA GTTCTGGTCTCCTTTTGACTGGACTGTGGCTCTGAACCTTGAGCATAGTACCACGGACTCCGTGGGCGCTCAATAAACACACATGAGAAC >In-frame_WNK1_ENST00000315939_chr12_971436_+_PRMT8_ENST00000452611_chr12_3649772_+_3892nt CCGGCCCTTCGCCTCTGGGCGATGGGCGACCTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGAC CGGGAGCCGGGCCGCGGCCTTCCCTCGCCCGCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGT CCCGTGCTCGCGGTGCCGCCGCCCTCTGGGCCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTC GACTCGGTGCCGGCCCCTGGCCCTCCCCTCATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATG CGGACCGTGCGGCGCTAACCCCCGTGGCTCAGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGC CCCCGCCGCAGCTGGGCCCAGCGGTCCGCCTGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCG CCCGGCCGCGGTTCCCTGCAGACCTCTGCGCGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTC CAGCGAACCGACCATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAA GAATGGCTCCAGCTCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCG CCGCCGCCACACTATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTG TGACTCCAATGCCACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCC ACCGGAGCCCCACCGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACA GGCCGTCGCGGGCCCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGA GGAGCCGCCGCCGGCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGA GCTGGAGACCAAGGCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTA CAAAGGTCTGGACACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGGATCGAAAATTAACAAAGTCTGAGAGGCAGAGATTTAA AGAAGAAGCTGAAATGTTAAAAGGTCTTCAGCATCCCAATATTGTTAGATTTTATGATTCCTGGGAATCCACAGTAAAAGGAAAGAAGTG CATTGTTTTGGTGACTGAACTTATGACGTCTGGAACACTTAAAACGTATCTGAAAAGGTTTAAAGTGATGAAGATCAAAGTTCTAAGAAG CTGGTGCCGTCAGATCCTTAAAGGTCTTCAGTTTCTTCATACTCGAACTCCACCTATCATTCACCGCGATCTTAAATGTGACAACATCTT TATCACCGGCCCTACTGGCTCAGTCAAGATTGGAGACCTCGGTCTGGCAACCCTGAAGCGGGCTTCTTTTGCCAAGAGTGTGATAGGTAC CCCAGAGTTCATGGCCCCTGAGATGTATGAGGAGAAATATGATGAATCCGTTGACGTTTATGCTTTTGGGATGTGCATGCTTGAGATGGC TACATCTGAATATCCTTACTCGGAGTGCCAAAATGCTGCACAGATCTACCGTCGCGTGACCAGTGGGGTGAAGCCAGCCAGTTTTGACAA AGTAGCAATTCCTGAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGATATTCCATCAAAGACCTTTTGAACCA TGCCTTCTTCCAAGAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAAATAGCCATAAAATTATGGCTACGTAT TGAAGATATTAAGAAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGATTTAGAGAGAGATGTCCCAGAAGATGT TGCACAAGAAATGGTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCTATCAAAGACAGAGTATCATTAATTAA GAGGAAACGAGAGCAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGCAGTCTCAAACAGCAGGTAGAACAATC CAGTGCTTCCCAGACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCTACCACTTCAGCTTCAGTTTCTACACA AGTAGAACCTGAAGAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATATCTGTGTTATCTGATGGGACGGTTGA CAGTGGTCAGGGATCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATATGGTTCCCAACATGAACAGGCACATTC TACAGGCACAGTCCCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTATATCCACCCTCAAGTGTGGTGAACAG CCCCCCCTCCCAGCCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTGTCCACTCAACCCAGCTGCCCAGGACG GGGCAAGATGTCCAAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCCTATGCCCACTTTGGGATCCACGAGGA AATGCTGAAGGATGAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTGTTCAAGGACAAAGTGGTACTGGATGT GGGGAGTGGTACTGGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGGATCGAATGCTCCAGTATTTCTGACTA CTCAGAGAAGATCATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTGGAAGAGGTGGAGCTGCCTGTGGAGAA GGTGGACATCATCATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACGGTGATCTTTGCCAGGGACAAGTGGCT GAAACCTGGAGGGCTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGACAGTACAAGGACTTCAAAATCCACTG GTGGGAGAATGTCTATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTAGTGGACATCGTGGATCCAAAGCAAGT GGTGACCAATGCCTGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCGTTCACATCTGCATTCTGCCTGCAGAT ACAGCGCAACGACTACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCACAAGAAAATGGGGTTTTCCACAGCCCC TGATGCTCCCTACACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGGAGGGGGGAGGAAATCTACGGGACCAT ATCCATGAAGCCAAATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAGGGACAGCTGTGTGAAACATCTGTATC >In-frame_WNK1_ENST00000315939_chr12_971436_+_PRMT8_ENST00000382622_chr12_3649772_+_4683nt CCGGCCCTTCGCCTCTGGGCGATGGGCGACCTGTGAGGCCGGTCCCCATCGCTGGGGGCGCGTGTGGGAGGAGGCGGCCGCCCGAGTGAC CGGGAGCCGGGCCGCGGCCTTCCCTCGCCCGCCTCGGCCCCTCCCACTCCTCTGCCCCGGGGCCGCCACCGCCCGGGCGTCGGACCTGGT CCCGTGCTCGCGGTGCCGCCGCCCTCTGGGCCTAGCCCGCCCAGCTCGGCGAGCGGCGGCAGTGGGAGCCGCGTCCGCCGCATCCGCCTC GACTCGGTGCCGGCCCCTGGCCCTCCCCTCATGACTGCGGCGCCTCTGCTGCCACCGCCCGCCCGGCCGCCGCTCGCCGCAGGATGGATG CGGACCGTGCGGCGCTAACCCCCGTGGCTCAGCTCCCGAATCGCCCGCCTTCGAGCCCTCCTCGTGAGCCGCAGCAGCCTCGGTGCCAGC CCCCGCCGCAGCTGGGCCCAGCGGTCCGCCTGTCCCTCGTTGCGGCTTGTCGGTGCTGAGTGAGGCGTCGTCCGGGTCGGCGCGAACCCG CCCGGCCGCGGTTCCCTGCAGACCTCTGCGCGGGCGGCTCGGCCCTTCACGCCCTTTTCGTTCACGAATCCGAGCCCGCTCGCCTCTCTC CAGCGAACCGACCATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAA GAATGGCTCCAGCTCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCG CCGCCGCCACACTATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTG TGACTCCAATGCCACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCC ACCGGAGCCCCACCGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACA GGCCGTCGCGGGCCCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGA GGAGCCGCCGCCGGCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGA GCTGGAGACCAAGGCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTA CAAAGGTCTGGACACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGGATCGAAAATTAACAAAGTCTGAGAGGCAGAGATTTAA AGAAGAAGCTGAAATGTTAAAAGGTCTTCAGCATCCCAATATTGTTAGATTTTATGATTCCTGGGAATCCACAGTAAAAGGAAAGAAGTG CATTGTTTTGGTGACTGAACTTATGACGTCTGGAACACTTAAAACGTATCTGAAAAGGTTTAAAGTGATGAAGATCAAAGTTCTAAGAAG CTGGTGCCGTCAGATCCTTAAAGGTCTTCAGTTTCTTCATACTCGAACTCCACCTATCATTCACCGCGATCTTAAATGTGACAACATCTT TATCACCGGCCCTACTGGCTCAGTCAAGATTGGAGACCTCGGTCTGGCAACCCTGAAGCGGGCTTCTTTTGCCAAGAGTGTGATAGGTAC CCCAGAGTTCATGGCCCCTGAGATGTATGAGGAGAAATATGATGAATCCGTTGACGTTTATGCTTTTGGGATGTGCATGCTTGAGATGGC TACATCTGAATATCCTTACTCGGAGTGCCAAAATGCTGCACAGATCTACCGTCGCGTGACCAGTGGGGTGAAGCCAGCCAGTTTTGACAA AGTAGCAATTCCTGAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGATATTCCATCAAAGACCTTTTGAACCA TGCCTTCTTCCAAGAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAAATAGCCATAAAATTATGGCTACGTAT TGAAGATATTAAGAAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGATTTAGAGAGAGATGTCCCAGAAGATGT TGCACAAGAAATGGTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCTATCAAAGACAGAGTATCATTAATTAA GAGGAAACGAGAGCAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGCAGTCTCAAACAGCAGGTAGAACAATC CAGTGCTTCCCAGACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCTACCACTTCAGCTTCAGTTTCTACACA AGTAGAACCTGAAGAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATATCTGTGTTATCTGATGGGACGGTTGA CAGTGGTCAGGGATCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATATGGTTCCCAACATGAACAGGCACATTC TACAGGCACAGTCCCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTATATCCACCCTCAAGTGTGGTGAACAG CCCCCCCTCCCAGCCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTGTCCACTCAACCCAGCTGCCCAGGACG GGGCAAGATGTCCAAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCCTATGCCCACTTTGGGATCCACGAGGA AATGCTGAAGGATGAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTGTTCAAGGACAAAGTGGTACTGGATGT GGGGAGTGGTACTGGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGGATCGAATGCTCCAGTATTTCTGACTA CTCAGAGAAGATCATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTGGAAGAGGTGGAGCTGCCTGTGGAGAA GGTGGACATCATCATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACGGTGATCTTTGCCAGGGACAAGTGGCT GAAACCTGGAGGGCTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGACAGTACAAGGACTTCAAAATCCACTG GTGGGAGAATGTCTATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTAGTGGACATCGTGGATCCAAAGCAAGT GGTGACCAATGCCTGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCGTTCACATCTGCATTCTGCCTGCAGAT ACAGCGCAACGACTACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCACAAGAAAATGGGGTTTTCCACAGCCCC TGATGCTCCCTACACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGGAGGGGGGAGGAAATCTACGGGACCAT ATCCATGAAGCCAAATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAGGGACAGCTGTGTGAAACATCTGTATC TAATGACTACAAAATGCGTTAGCACACGTGGGAAGCTGCAGAGAGCAACGAGAAAAGGAACTCTCACCTCGATCTGCCGTGCCGTCCCAA AGAATACCGTTTGCAGGACTACACACTTGAAAACCAGAGTTTTCAACTCTGCCTTGAAGATTGGTGAACTCCCCAGGGCTCCCGTGGGCT CTGCCACTGGACAGAAGGCCTCCAGCTCCTCCGCTCTGCCCTGGTAGCCCTTCACGAAGGCTTTGTGTTGCCAACAAAGAGCGACCTGGC GTGCTGTGGCTGGGCCCCGAGGGTGGAAACGTATTCGCGTCTCCCCGTCTCCTCCTTAACTGTGACTCTCCGGGTCTTCTGAGTTTTGCA TGCTGCGGGTGTCTAGGACAGATTGCTTCCACTAGAACCTGGAGACATAGCATCTTTGATAGCATAAGCCAGATTATCTGTGTGTGCGGT GGTGTGCGTGTGCGTGCATGTGTGAATGTGAGCAGCATAGTTGATATTTACCCACAAACACCTGTATATGCGTGCATATACAACCAAGTG GGTAGACCTAGGTGTTCTCTCAGAGGGGTGTGTGTGTGTGTGCGTGCGCGTGTGCCTAGAATATATATTACTCTCAGAGGAGATTCTGTT GCTTTTGAATAGGAATTTGTTTTGTGATTAGTTCGCCCCTTCCCCACCCCTTACCAGATGTTAAGCAGCTATGAAACATTCTCTGTACTA GTTCTGGTCTCCTTTTGACTGGACTGTGGCTCTGAACCTTGAGCATAGTACCACGGACTCCGTGGGCGCTCAATAAACACACATGAGAAC >In-frame_WNK1_ENST00000530271_chr12_971436_+_PRMT8_ENST00000452611_chr12_3649772_+_3249nt ATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGC TCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACT ATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCC ACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCAC CGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGC CCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCG GCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAG GCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGAC ACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGGATCGAAAATTAACAAAGTCTGAGAGGCAGAGATTTAAAGAAGAAGCTGAA ATGTTAAAAGGTCTTCAGCATCCCAATATTGTTAGATTTTATGATTCCTGGGAATCCACAGTAAAAGGAAAGAAGTGCATTGTTTTGGTG ACTGAACTTATGACGTCTGGAACACTTAAAACGTATCTGAAAAGGTTTAAAGTGATGAAGATCAAAGTTCTAAGAAGCTGGTGCCGTCAG ATCCTTAAAGGTCTTCAGTTTCTTCATACTCGAACTCCACCTATCATTCACCGCGATCTTAAATGTGACAACATCTTTATCACCGGCCCT ACTGGCTCAGTCAAGATTGGAGACCTCGGTCTGGCAACCCTGAAGCGGGCTTCTTTTGCCAAGAGTGTGATAGGTACCCCAGAGTTCATG GCCCCTGAGATGTATGAGGAGAAATATGATGAATCCGTTGACGTTTATGCTTTTGGGATGTGCATGCTTGAGATGGCTACATCTGAATAT CCTTACTCGGAGTGCCAAAATGCTGCACAGATCTACCGTCGCGTGACCAGTGGGGTGAAGCCAGCCAGTTTTGACAAAGTAGCAATTCCT GAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGATATTCCATCAAAGACCTTTTGAACCATGCCTTCTTCCAA GAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAAATAGCCATAAAATTATGGCTACGTATTGAAGATATTAAG AAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGATTTAGAGAGAGATGTCCCAGAAGATGTTGCACAAGAAATG GTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCTATCAAAGACAGAGTATCATTAATTAAGAGGAAACGAGAG CAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGCAGTCTCAAACAGCAGGTAGAACAATCCAGTGCTTCCCAG ACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCTACCACTTCAGCTTCAGTTTCTACACAAGTAGAACCTGAA GAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATATCTGTGTTATCTGATGGGACGGTTGACAGTGGTCAGGGA TCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATATGGTTCCCAACATGAACAGGCACATTCTACAGGCACAGTC CCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTATATCCACCCTCAAGTGTGGTGAACAGCCCCCCCTCCCAG CCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTGTCCACTCAACCCAGCTGCCCAGGACGGGGCAAGATGTCC AAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCCTATGCCCACTTTGGGATCCACGAGGAAATGCTGAAGGAT GAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTGTTCAAGGACAAAGTGGTACTGGATGTGGGGAGTGGTACT GGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGGATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATC ATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTGGAAGAGGTGGAGCTGCCTGTGGAGAAGGTGGACATCATC ATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACGGTGATCTTTGCCAGGGACAAGTGGCTGAAACCTGGAGGG CTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGACAGTACAAGGACTTCAAAATCCACTGGTGGGAGAATGTC TATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTAGTGGACATCGTGGATCCAAAGCAAGTGGTGACCAATGCC TGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCGTTCACATCTGCATTCTGCCTGCAGATACAGCGCAACGAC TACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCACAAGAAAATGGGGTTTTCCACAGCCCCTGATGCTCCCTAC ACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGGAGGGGGGAGGAAATCTACGGGACCATATCCATGAAGCCA AATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAGGGACAGCTGTGTGAAACATCTGTATCTAATGACTACAAA >In-frame_WNK1_ENST00000530271_chr12_971436_+_PRMT8_ENST00000382622_chr12_3649772_+_4040nt ATGTCTGGCGGCGCCGCAGAGAAGCAGAGCAGCACTCCCGGTTCCCTGTTCCTCTCGCCGCCGGCTCCTGCCCCCAAGAATGGCTCCAGC TCCGATTCCTCCGTGGGGGAGAAACTGGGAGCCGCGGCCGCCGACGCTGTGACCGGCAGGACCGAGGAGTACAGGCGCCGCCGCCACACT ATGGACAAGGACAGCCGTGGGGCGGCCGCGACCACTACCACCACTGAGCACCGCTTCTTCCGCCGGAGCGTCATCTGTGACTCCAATGCC ACTGCACTGGAGCTTCCCGGCCTTCCTCTTTCCCTGCCCCAGCCCAGCATCCCCGCGGCTGTCCCGCAGAGTGCTCCACCGGAGCCCCAC CGGGAAGAGACCGTGACCGCCACCGCCACTTCCCAGGTAGCCCAGCAGCCTCCAGCCGCTGCCGCCCCTGGGGAACAGGCCGTCGCGGGC CCTGCCCCCTCGACTGTCCCCAGCAGTACCAGCAAAGACCGCCCAGTGTCCCAGCCTAGCCTTGTGGGGAGCAAAGAGGAGCCGCCGCCG GCGAGAAGTGGCAGCGGCGGCGGCAGCGCCAAGGAGCCACAGGAGGAACGGAGCCAGCAGCAGGATGATATCGAAGAGCTGGAGACCAAG GCCGTGGGAATGTCTAACGATGGCCGCTTTCTCAAGTTTGACATCGAAATCGGCAGAGGCTCCTTTAAGACGGTCTACAAAGGTCTGGAC ACTGAAACCACCGTGGAAGTCGCCTGGTGTGAACTGCAGGATCGAAAATTAACAAAGTCTGAGAGGCAGAGATTTAAAGAAGAAGCTGAA ATGTTAAAAGGTCTTCAGCATCCCAATATTGTTAGATTTTATGATTCCTGGGAATCCACAGTAAAAGGAAAGAAGTGCATTGTTTTGGTG ACTGAACTTATGACGTCTGGAACACTTAAAACGTATCTGAAAAGGTTTAAAGTGATGAAGATCAAAGTTCTAAGAAGCTGGTGCCGTCAG ATCCTTAAAGGTCTTCAGTTTCTTCATACTCGAACTCCACCTATCATTCACCGCGATCTTAAATGTGACAACATCTTTATCACCGGCCCT ACTGGCTCAGTCAAGATTGGAGACCTCGGTCTGGCAACCCTGAAGCGGGCTTCTTTTGCCAAGAGTGTGATAGGTACCCCAGAGTTCATG GCCCCTGAGATGTATGAGGAGAAATATGATGAATCCGTTGACGTTTATGCTTTTGGGATGTGCATGCTTGAGATGGCTACATCTGAATAT CCTTACTCGGAGTGCCAAAATGCTGCACAGATCTACCGTCGCGTGACCAGTGGGGTGAAGCCAGCCAGTTTTGACAAAGTAGCAATTCCT GAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGATATTCCATCAAAGACCTTTTGAACCATGCCTTCTTCCAA GAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAAATAGCCATAAAATTATGGCTACGTATTGAAGATATTAAG AAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGATTTAGAGAGAGATGTCCCAGAAGATGTTGCACAAGAAATG GTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCTATCAAAGACAGAGTATCATTAATTAAGAGGAAACGAGAG CAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGCAGTCTCAAACAGCAGGTAGAACAATCCAGTGCTTCCCAG ACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCTACCACTTCAGCTTCAGTTTCTACACAAGTAGAACCTGAA GAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATATCTGTGTTATCTGATGGGACGGTTGACAGTGGTCAGGGA TCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATATGGTTCCCAACATGAACAGGCACATTCTACAGGCACAGTC CCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTATATCCACCCTCAAGTGTGGTGAACAGCCCCCCCTCCCAG CCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTGTCCACTCAACCCAGCTGCCCAGGACGGGGCAAGATGTCC AAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCCTATGCCCACTTTGGGATCCACGAGGAAATGCTGAAGGAT GAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTGTTCAAGGACAAAGTGGTACTGGATGTGGGGAGTGGTACT GGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGGATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATC ATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTGGAAGAGGTGGAGCTGCCTGTGGAGAAGGTGGACATCATC ATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACGGTGATCTTTGCCAGGGACAAGTGGCTGAAACCTGGAGGG CTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGACAGTACAAGGACTTCAAAATCCACTGGTGGGAGAATGTC TATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTAGTGGACATCGTGGATCCAAAGCAAGTGGTGACCAATGCC TGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCGTTCACATCTGCATTCTGCCTGCAGATACAGCGCAACGAC TACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCACAAGAAAATGGGGTTTTCCACAGCCCCTGATGCTCCCTAC ACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGGAGGGGGGAGGAAATCTACGGGACCATATCCATGAAGCCA AATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAGGGACAGCTGTGTGAAACATCTGTATCTAATGACTACAAA ATGCGTTAGCACACGTGGGAAGCTGCAGAGAGCAACGAGAAAAGGAACTCTCACCTCGATCTGCCGTGCCGTCCCAAAGAATACCGTTTG CAGGACTACACACTTGAAAACCAGAGTTTTCAACTCTGCCTTGAAGATTGGTGAACTCCCCAGGGCTCCCGTGGGCTCTGCCACTGGACA GAAGGCCTCCAGCTCCTCCGCTCTGCCCTGGTAGCCCTTCACGAAGGCTTTGTGTTGCCAACAAAGAGCGACCTGGCGTGCTGTGGCTGG GCCCCGAGGGTGGAAACGTATTCGCGTCTCCCCGTCTCCTCCTTAACTGTGACTCTCCGGGTCTTCTGAGTTTTGCATGCTGCGGGTGTC TAGGACAGATTGCTTCCACTAGAACCTGGAGACATAGCATCTTTGATAGCATAAGCCAGATTATCTGTGTGTGCGGTGGTGTGCGTGTGC GTGCATGTGTGAATGTGAGCAGCATAGTTGATATTTACCCACAAACACCTGTATATGCGTGCATATACAACCAAGTGGGTAGACCTAGGT GTTCTCTCAGAGGGGTGTGTGTGTGTGTGCGTGCGCGTGTGCCTAGAATATATATTACTCTCAGAGGAGATTCTGTTGCTTTTGAATAGG AATTTGTTTTGTGATTAGTTCGCCCCTTCCCCACCCCTTACCAGATGTTAAGCAGCTATGAAACATTCTCTGTACTAGTTCTGGTCTCCT >In-frame_WNK1_ENST00000340908_chr12_971436_+_PRMT8_ENST00000452611_chr12_3649772_+_2028nt ATGGATATTAAAAAGAAAGATTTTTGCTCAGTATTTGTCATCATAAATTCTCATTGCTGCTGCTGCCCTCAAAAGGATTGTATAAATGAG GGGGTGAAGCCAGCCAGTTTTGACAAAGTAGCAATTCCTGAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGA TATTCCATCAAAGACCTTTTGAACCATGCCTTCTTCCAAGAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAA ATAGCCATAAAATTATGGCTACGTATTGAAGATATTAAGAAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGAT TTAGAGAGAGATGTCCCAGAAGATGTTGCACAAGAAATGGTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCT ATCAAAGACAGAGTATCATTAATTAAGAGGAAACGAGAGCAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGC AGTCTCAAACAGCAGGTAGAACAATCCAGTGCTTCCCAGACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCT ACCACTTCAGCTTCAGTTTCTACACAAGTAGAACCTGAAGAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATA TCTGTGTTATCTGATGGGACGGTTGACAGTGGTCAGGGATCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATAT GGTTCCCAACATGAACAGGCACATTCTACAGGCACAGTCCCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTA TATCCACCCTCAAGTGTGGTGAACAGCCCCCCCTCCCAGCCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTG TCCACTCAACCCAGCTGCCCAGGACGGGGCAAGATGTCCAAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCC TATGCCCACTTTGGGATCCACGAGGAAATGCTGAAGGATGAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTG TTCAAGGACAAAGTGGTACTGGATGTGGGGAGTGGTACTGGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGG ATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATCATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTG GAAGAGGTGGAGCTGCCTGTGGAGAAGGTGGACATCATCATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACG GTGATCTTTGCCAGGGACAAGTGGCTGAAACCTGGAGGGCTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGA CAGTACAAGGACTTCAAAATCCACTGGTGGGAGAATGTCTATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTA GTGGACATCGTGGATCCAAAGCAAGTGGTGACCAATGCCTGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCG TTCACATCTGCATTCTGCCTGCAGATACAGCGCAACGACTACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCAC AAGAAAATGGGGTTTTCCACAGCCCCTGATGCTCCCTACACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGG AGGGGGGAGGAAATCTACGGGACCATATCCATGAAGCCAAATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAG >In-frame_WNK1_ENST00000340908_chr12_971436_+_PRMT8_ENST00000382622_chr12_3649772_+_2819nt ATGGATATTAAAAAGAAAGATTTTTGCTCAGTATTTGTCATCATAAATTCTCATTGCTGCTGCTGCCCTCAAAAGGATTGTATAAATGAG GGGGTGAAGCCAGCCAGTTTTGACAAAGTAGCAATTCCTGAAGTGAAGGAAATTATTGAAGGATGCATACGACAAAACAAAGATGAAAGA TATTCCATCAAAGACCTTTTGAACCATGCCTTCTTCCAAGAGGAAACAGGAGTACGGGTAGAATTAGCAGAAGAAGATGATGGAGAAAAA ATAGCCATAAAATTATGGCTACGTATTGAAGATATTAAGAAATTAAAGGGAAAATACAAAGATAATGAAGCTATTGAGTTTTCTTTTGAT TTAGAGAGAGATGTCCCAGAAGATGTTGCACAAGAAATGGTAGAGTCTGGGTATGTCTGTGAAGGTGATCACAAGACCATGGCTAAAGCT ATCAAAGACAGAGTATCATTAATTAAGAGGAAACGAGAGCAGCGGCAGTTGGTACGGGAGGAGCAAGAAAAAAAAAAGCAGGAAGAGAGC AGTCTCAAACAGCAGGTAGAACAATCCAGTGCTTCCCAGACAGGAATCAAGCAGCTCCCTTCTGCTAGCACCGGCATACCTACTGCTTCT ACCACTTCAGCTTCAGTTTCTACACAAGTAGAACCTGAAGAACCTGAGGCAGATCAACATCAACAACTACAGTACCAGCAACCCAGTATA TCTGTGTTATCTGATGGGACGGTTGACAGTGGTCAGGGATCCTCTGTCTTCACAGAATCTCGAGTGAGCAGCCAACAGACAGTTTCATAT GGTTCCCAACATGAACAGGCACATTCTACAGGCACAGTCCCAGGGCATATACCTTCTACTGTCCAAGCACAGTCTCAGCCCCATGGGGTA TATCCACCCTCAAGTGTGGTGAACAGCCCCCCCTCCCAGCCCCCCCAGCCCGTCGTCCCTGCTAAGCCCGTGCAATGCGTCCATCATGTG TCCACTCAACCCAGCTGCCCAGGACGGGGCAAGATGTCCAAGCTGCTGAACCCAGAGGAGATGACCTCGAGAGATTATTACTTCGACTCC TATGCCCACTTTGGGATCCACGAGGAAATGCTGAAGGATGAGGTGCGGACTCTCACTTACCGGAACTCCATGTACCACAACAAGCACGTG TTCAAGGACAAAGTGGTACTGGATGTGGGGAGTGGTACTGGGATCCTTTCCATGTTCGCTGCCAAGGCAGGGGCCAAGAAGGTGTTTGGG ATCGAATGCTCCAGTATTTCTGACTACTCAGAGAAGATCATTAAGGCCAACCACTTGGACAACATCATCACCATATTTAAGGGTAAAGTG GAAGAGGTGGAGCTGCCTGTGGAGAAGGTGGACATCATCATCAGCGAGTGGATGGGCTACTGTCTGTTCTATGAGTCCATGCTCAACACG GTGATCTTTGCCAGGGACAAGTGGCTGAAACCTGGAGGGCTTATGTTTCCAGACCGGGCAGCTTTGTACGTGGTAGCGATTGAAGACAGA CAGTACAAGGACTTCAAAATCCACTGGTGGGAGAATGTCTATGGCTTTGACATGACCTGCATCCGGGACGTGGCCATGAAGGAGCCTCTA GTGGACATCGTGGATCCAAAGCAAGTGGTGACCAATGCCTGTTTGATAAAGGAGGTGGACATTTACACAGTGAAGACGGAAGAGCTATCG TTCACATCTGCATTCTGCCTGCAGATACAGCGCAACGACTACGTCCACGCCCTGGTCACCTATTTTAATATTGAATTTACCAAGTGCCAC AAGAAAATGGGGTTTTCCACAGCCCCTGATGCTCCCTACACCCACTGGAAGCAGACCGTCTTCTACTTGGAAGATTACCTCACTGTCCGG AGGGGGGAGGAAATCTACGGGACCATATCCATGAAGCCAAATGCCAAAAATGTGCGAGACCTCGATTTCACAGTAGACTTGGATTTTAAG GGACAGCTGTGTGAAACATCTGTATCTAATGACTACAAAATGCGTTAGCACACGTGGGAAGCTGCAGAGAGCAACGAGAAAAGGAACTCT CACCTCGATCTGCCGTGCCGTCCCAAAGAATACCGTTTGCAGGACTACACACTTGAAAACCAGAGTTTTCAACTCTGCCTTGAAGATTGG TGAACTCCCCAGGGCTCCCGTGGGCTCTGCCACTGGACAGAAGGCCTCCAGCTCCTCCGCTCTGCCCTGGTAGCCCTTCACGAAGGCTTT GTGTTGCCAACAAAGAGCGACCTGGCGTGCTGTGGCTGGGCCCCGAGGGTGGAAACGTATTCGCGTCTCCCCGTCTCCTCCTTAACTGTG ACTCTCCGGGTCTTCTGAGTTTTGCATGCTGCGGGTGTCTAGGACAGATTGCTTCCACTAGAACCTGGAGACATAGCATCTTTGATAGCA TAAGCCAGATTATCTGTGTGTGCGGTGGTGTGCGTGTGCGTGCATGTGTGAATGTGAGCAGCATAGTTGATATTTACCCACAAACACCTG TATATGCGTGCATATACAACCAAGTGGGTAGACCTAGGTGTTCTCTCAGAGGGGTGTGTGTGTGTGTGCGTGCGCGTGTGCCTAGAATAT ATATTACTCTCAGAGGAGATTCTGTTGCTTTTGAATAGGAATTTGTTTTGTGATTAGTTCGCCCCTTCCCCACCCCTTACCAGATGTTAA GCAGCTATGAAACATTCTCTGTACTAGTTCTGGTCTCCTTTTGACTGGACTGTGGCTCTGAACCTTGAGCATAGTACCACGGACTCCGTG |
Top |
FusionGenePPI for WNK1_PRMT8 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| WNK1 | E2F3, CLTC, FLNC, ATP8, PRKAR1A, PRKAR1B, SLC9A1, ZYX, CSDE1, TSC22D1, BAG3, RANBP9, COPS5, TNRC6A, ZNF106, YWHAE, YWHAZ, MAP2K1, YWHAG, WNK1, WNK2, GLIS2, MYC, SGK1, NEDD4L, ATXN1, KLHL3, VCP, YWHAQ, MMS19, KLHL2, PFKP, ARAF, PVR, UPF2, YWHAB, EIF2B2, EIF3K, HNRNPD, ADRB2, FAM96B, FHL3, UBE2I, METTL6, TSC22D4, AAMP, MED4, XPO1, CDC42, CLTB, GAK, PICALM, GTSE1, SPATA1, AARSD1, HAO2, HSPA8, BAG4, SERPINB13, RAPGEF5, STAMBPL1, MLF1, PLEC, AAK1, TRIM25 | PRMT8 | PRMT8, HNRNPA1, COIL, SYNCRIP, TAF15, PRMT1, HIST1H4A, GPATCH2L, CEP162, OFCC1, PPARA, SERBP1, VHL, DCAF8, ZNF451, EWSR1, NEFM, VIM, INA, HNRNPU, FAM120A, DHX9, HNRNPR, BCLAF1, THRAP3, LSM14A, PRRC2C, HNRNPUL2, CHTOP, FBXW11, SCAF11, ALYREF, ANGEL2, HNRNPK, GIMAP2, SPDEF, TIGD7, ZSCAN1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for WNK1_PRMT8 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for WNK1_PRMT8 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | WNK1 | C0020538 | Hypertensive disease | 1 | CTD_human |
| Hgene | WNK1 | C0022658 | Kidney Diseases | 1 | CTD_human |
| Hgene | WNK1 | C0033805 | Pseudohypoaldosteronism | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|