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Fusion gene ID: 41921 |
FusionGeneSummary for WDR74_SNHG1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: WDR74_SNHG1 | Fusion gene ID: 41921 | Hgene | Tgene | Gene symbol | WDR74 | SNHG1 | Gene ID | 54663 | 23642 |
| Gene name | WD repeat domain 74 | small nucleolar RNA host gene 1 | |
| Synonyms | - | LINC00057|NCRNA00057|U22HG|UHG|lncRNA16 | |
| Cytomap | 11q12.3 | 11q12.3 | |
| Type of gene | protein-coding | ncRNA | |
| Description | WD repeat-containing protein 74NOP seven-associated protein 1 | U22 snoRNA hostlong intergenic non-protein coding RNA 57small nucleolar RNA host gene 1 (non-protein coding) | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q6RFH5 | ||
| Ensembl transtripts involved in fusion gene | ENST00000311713, ENST00000278856, ENST00000529106, ENST00000525239, ENST00000525752, ENST00000540620, | ENST00000384756, ENST00000364799, ENST00000384693, ENST00000383926, ENST00000516331, ENST00000384706, ENST00000363981, ENST00000384147, ENST00000365607, | |
| Fusion gene scores | * DoF score | 27 X 13 X 4=1404 | 7 X 7 X 5=245 |
| # samples | 28 | 8 | |
| ** MAII score | log2(28/1404*10)=-2.32604420335959 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/245*10)=-1.61470984411521 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: WDR74 [Title/Abstract] AND SNHG1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BLCA | TCGA-G2-A2EO-01A | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| TCGA | LD | OV | TCGA-24-2267-01A | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000311713 | ENST00000384756 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000311713 | ENST00000364799 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000311713 | ENST00000384693 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000311713 | ENST00000383926 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000311713 | ENST00000516331 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000311713 | ENST00000384706 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000311713 | ENST00000363981 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000311713 | ENST00000384147 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000311713 | ENST00000365607 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000278856 | ENST00000384756 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000278856 | ENST00000364799 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000278856 | ENST00000384693 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000278856 | ENST00000383926 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000278856 | ENST00000516331 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000278856 | ENST00000384706 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000278856 | ENST00000363981 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000278856 | ENST00000384147 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000278856 | ENST00000365607 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000529106 | ENST00000384756 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000529106 | ENST00000364799 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000529106 | ENST00000384693 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000529106 | ENST00000383926 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000529106 | ENST00000516331 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000529106 | ENST00000384706 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000529106 | ENST00000363981 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000529106 | ENST00000384147 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000529106 | ENST00000365607 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525239 | ENST00000384756 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525239 | ENST00000364799 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525239 | ENST00000384693 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525239 | ENST00000383926 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525239 | ENST00000516331 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525239 | ENST00000384706 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525239 | ENST00000363981 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525239 | ENST00000384147 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525239 | ENST00000365607 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525752 | ENST00000384756 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525752 | ENST00000364799 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525752 | ENST00000384693 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525752 | ENST00000383926 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525752 | ENST00000516331 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525752 | ENST00000384706 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525752 | ENST00000363981 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525752 | ENST00000384147 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000525752 | ENST00000365607 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5UTR-intron | ENST00000540620 | ENST00000384756 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5UTR-intron | ENST00000540620 | ENST00000364799 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5UTR-intron | ENST00000540620 | ENST00000384693 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5UTR-intron | ENST00000540620 | ENST00000383926 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5UTR-intron | ENST00000540620 | ENST00000516331 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5UTR-intron | ENST00000540620 | ENST00000384706 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5UTR-intron | ENST00000540620 | ENST00000363981 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5UTR-intron | ENST00000540620 | ENST00000384147 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5UTR-intron | ENST00000540620 | ENST00000365607 | WDR74 | chr11 | 62602903 | - | SNHG1 | chr11 | 62620311 | - |
| 5CDS-intron | ENST00000311713 | ENST00000384756 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000311713 | ENST00000364799 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000311713 | ENST00000384693 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000311713 | ENST00000383926 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000311713 | ENST00000516331 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000311713 | ENST00000384706 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000311713 | ENST00000363981 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000311713 | ENST00000384147 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000311713 | ENST00000365607 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000278856 | ENST00000384756 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000278856 | ENST00000364799 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000278856 | ENST00000384693 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000278856 | ENST00000383926 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000278856 | ENST00000516331 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000278856 | ENST00000384706 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000278856 | ENST00000363981 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000278856 | ENST00000384147 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000278856 | ENST00000365607 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000529106 | ENST00000384756 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000529106 | ENST00000364799 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000529106 | ENST00000384693 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000529106 | ENST00000383926 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000529106 | ENST00000516331 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000529106 | ENST00000384706 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000529106 | ENST00000363981 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000529106 | ENST00000384147 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000529106 | ENST00000365607 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525239 | ENST00000384756 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525239 | ENST00000364799 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525239 | ENST00000384693 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525239 | ENST00000383926 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525239 | ENST00000516331 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525239 | ENST00000384706 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525239 | ENST00000363981 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525239 | ENST00000384147 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525239 | ENST00000365607 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525752 | ENST00000384756 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525752 | ENST00000364799 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525752 | ENST00000384693 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525752 | ENST00000383926 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525752 | ENST00000516331 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525752 | ENST00000384706 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525752 | ENST00000363981 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525752 | ENST00000384147 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5CDS-intron | ENST00000525752 | ENST00000365607 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5UTR-intron | ENST00000540620 | ENST00000384756 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5UTR-intron | ENST00000540620 | ENST00000364799 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5UTR-intron | ENST00000540620 | ENST00000384693 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5UTR-intron | ENST00000540620 | ENST00000383926 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5UTR-intron | ENST00000540620 | ENST00000516331 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5UTR-intron | ENST00000540620 | ENST00000384706 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5UTR-intron | ENST00000540620 | ENST00000363981 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5UTR-intron | ENST00000540620 | ENST00000384147 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
| 5UTR-intron | ENST00000540620 | ENST00000365607 | WDR74 | chr11 | 62606586 | - | SNHG1 | chr11 | 62621536 | - |
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FusionProtFeatures for WDR74_SNHG1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| WDR74 | SNHG1 |