|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 41569 |
FusionGeneSummary for VPS26B_VPS26B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: VPS26B_VPS26B | Fusion gene ID: 41569 | Hgene | Tgene | Gene symbol | VPS26B | VPS26B | Gene ID | 112936 | 112936 |
| Gene name | VPS26, retromer complex component B | VPS26, retromer complex component B | |
| Synonyms | Pep8b | Pep8b | |
| Cytomap | 11q25 | 11q25 | |
| Type of gene | protein-coding | protein-coding | |
| Description | vacuolar protein sorting-associated protein 26Bvesicle protein sorting 26B | vacuolar protein sorting-associated protein 26Bvesicle protein sorting 26B | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q4G0F5 | Q4G0F5 | |
| Ensembl transtripts involved in fusion gene | ENST00000281187, ENST00000525095, ENST00000530402, | ENST00000281187, ENST00000525095, ENST00000530402, | |
| Fusion gene scores | * DoF score | 2 X 3 X 2=12 | 3 X 3 X 2=18 |
| # samples | 2 | 3 | |
| ** MAII score | log2(2/12*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: VPS26B [Title/Abstract] AND VPS26B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BI013828 | VPS26B | chr11 | 134116800 | + | VPS26B | chr11 | 134117181 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3UTR | ENST00000281187 | ENST00000281187 | VPS26B | chr11 | 134116800 | + | VPS26B | chr11 | 134117181 | - |
| 3UTR-intron | ENST00000281187 | ENST00000525095 | VPS26B | chr11 | 134116800 | + | VPS26B | chr11 | 134117181 | - |
| 3UTR-intron | ENST00000281187 | ENST00000530402 | VPS26B | chr11 | 134116800 | + | VPS26B | chr11 | 134117181 | - |
| intron-3UTR | ENST00000525095 | ENST00000281187 | VPS26B | chr11 | 134116800 | + | VPS26B | chr11 | 134117181 | - |
| intron-intron | ENST00000525095 | ENST00000525095 | VPS26B | chr11 | 134116800 | + | VPS26B | chr11 | 134117181 | - |
| intron-intron | ENST00000525095 | ENST00000530402 | VPS26B | chr11 | 134116800 | + | VPS26B | chr11 | 134117181 | - |
| intron-3UTR | ENST00000530402 | ENST00000281187 | VPS26B | chr11 | 134116800 | + | VPS26B | chr11 | 134117181 | - |
| intron-intron | ENST00000530402 | ENST00000525095 | VPS26B | chr11 | 134116800 | + | VPS26B | chr11 | 134117181 | - |
| intron-intron | ENST00000530402 | ENST00000530402 | VPS26B | chr11 | 134116800 | + | VPS26B | chr11 | 134117181 | - |
Top |
FusionProtFeatures for VPS26B_VPS26B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| VPS26B | VPS26B |