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Fusion gene ID: 41469 |
FusionGeneSummary for VIM_PEX1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: VIM_PEX1 | Fusion gene ID: 41469 | Hgene | Tgene | Gene symbol | VIM | PEX1 | Gene ID | 7431 | 339324 |
| Gene name | vimentin | zinc finger protein 260 | |
| Synonyms | - | OZRF1|PEX1|ZFP260 | |
| Cytomap | 10p13 | 19q13.12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | vimentin | zinc finger protein 260zfp-260 | |
| Modification date | 20180527 | 20180519 | |
| UniProtAcc | P08670 | O43933 | |
| Ensembl transtripts involved in fusion gene | ENST00000544301, ENST00000224237, ENST00000485947, | ENST00000438045, ENST00000248633, ENST00000428214, ENST00000541751, | |
| Fusion gene scores | * DoF score | 13 X 4 X 9=468 | 9 X 6 X 7=378 |
| # samples | 15 | 9 | |
| ** MAII score | log2(15/468*10)=-1.64154602908752 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/378*10)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: VIM [Title/Abstract] AND PEX1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SKCM | TCGA-D3-A2JO-06A | VIM | chr10 | 17279592 | + | PEX1 | chr7 | 92146729 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000544301 | ENST00000438045 | VIM | chr10 | 17279592 | + | PEX1 | chr7 | 92146729 | - |
| intron-intron | ENST00000544301 | ENST00000248633 | VIM | chr10 | 17279592 | + | PEX1 | chr7 | 92146729 | - |
| intron-intron | ENST00000544301 | ENST00000428214 | VIM | chr10 | 17279592 | + | PEX1 | chr7 | 92146729 | - |
| intron-intron | ENST00000544301 | ENST00000541751 | VIM | chr10 | 17279592 | + | PEX1 | chr7 | 92146729 | - |
| 5CDS-intron | ENST00000224237 | ENST00000438045 | VIM | chr10 | 17279592 | + | PEX1 | chr7 | 92146729 | - |
| 5CDS-intron | ENST00000224237 | ENST00000248633 | VIM | chr10 | 17279592 | + | PEX1 | chr7 | 92146729 | - |
| 5CDS-intron | ENST00000224237 | ENST00000428214 | VIM | chr10 | 17279592 | + | PEX1 | chr7 | 92146729 | - |
| 5CDS-intron | ENST00000224237 | ENST00000541751 | VIM | chr10 | 17279592 | + | PEX1 | chr7 | 92146729 | - |
| intron-intron | ENST00000485947 | ENST00000438045 | VIM | chr10 | 17279592 | + | PEX1 | chr7 | 92146729 | - |
| intron-intron | ENST00000485947 | ENST00000248633 | VIM | chr10 | 17279592 | + | PEX1 | chr7 | 92146729 | - |
| intron-intron | ENST00000485947 | ENST00000428214 | VIM | chr10 | 17279592 | + | PEX1 | chr7 | 92146729 | - |
| intron-intron | ENST00000485947 | ENST00000541751 | VIM | chr10 | 17279592 | + | PEX1 | chr7 | 92146729 | - |
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FusionProtFeatures for VIM_PEX1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| VIM | PEX1 |