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Fusion gene ID: 4132 |
FusionGeneSummary for BGN_FLNC |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: BGN_FLNC | Fusion gene ID: 4132 | Hgene | Tgene | Gene symbol | BGN | FLNC | Gene ID | 633 | 2318 |
| Gene name | biglycan | filamin C | |
| Synonyms | DSPG1|MRLS|PG-S1|PGI|SEMDX|SLRR1A | ABP-280|ABP280A|ABPA|ABPL|CMH26|FLN2|MFM5|MPD4|RCM5 | |
| Cytomap | Xq28 | 7q32.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | biglycanbone/cartilage proteoglycan-Idermatan sulphate proteoglycan Ismall leucine-rich protein 1A | filamin-CABP-280-like proteinABP-L, gamma filaminactin binding protein 280filamin C, gammafilamin-2gamma filamin | |
| Modification date | 20180522 | 20180522 | |
| UniProtAcc | P21810 | Q14315 | |
| Ensembl transtripts involved in fusion gene | ENST00000331595, ENST00000480756, | ENST00000325888, ENST00000346177, | |
| Fusion gene scores | * DoF score | 15 X 7 X 11=1155 | 1 X 1 X 1=1 |
| # samples | 17 | 1 | |
| ** MAII score | log2(17/1155*10)=-2.76428620016572 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: BGN [Title/Abstract] AND FLNC [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AW340724 | BGN | chrX | 152774754 | - | FLNC | chr7 | 128480617 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000331595 | ENST00000325888 | BGN | chrX | 152774754 | - | FLNC | chr7 | 128480617 | - |
| 3UTR-3CDS | ENST00000331595 | ENST00000346177 | BGN | chrX | 152774754 | - | FLNC | chr7 | 128480617 | - |
| 3UTR-3CDS | ENST00000480756 | ENST00000325888 | BGN | chrX | 152774754 | - | FLNC | chr7 | 128480617 | - |
| 3UTR-3CDS | ENST00000480756 | ENST00000346177 | BGN | chrX | 152774754 | - | FLNC | chr7 | 128480617 | - |
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FusionProtFeatures for BGN_FLNC |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| BGN | FLNC |