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Fusion gene ID: 41282 |
FusionGeneSummary for UTY_OTUD7A |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: UTY_OTUD7A | Fusion gene ID: 41282 | Hgene | Tgene | Gene symbol | UTY | OTUD7A | Gene ID | 7404 | 161725 |
| Gene name | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | OTU deubiquitinase 7A | |
| Synonyms | KDM6AL|KDM6C|UTY1 | C15orf16|C16ORF15|CEZANNE2|OTUD7 | |
| Cytomap | Yq11.221 | 15q13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | histone demethylase UTYubiquitous TPR motif protein UTYubiquitously transcribed TPR gene on Y chromosomeubiquitously transcribed tetratricopeptide repeat gene, Y chromosomeubiquitously transcribed tetratricopeptide repeat gene, Y-linkedubiquitously-t | OTU domain-containing protein 7AOTU domain-containing 7Acezanne 2zinc finger protein Cezanne 2 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | O14607 | Q8TE49 | |
| Ensembl transtripts involved in fusion gene | ENST00000331397, ENST00000382896, ENST00000537580, ENST00000362096, ENST00000329134, ENST00000538878, ENST00000540140, ENST00000545955, ENST00000474365, ENST00000382893, | ENST00000382902, ENST00000307050, | |
| Fusion gene scores | * DoF score | 2 X 2 X 1=4 | 2 X 2 X 2=8 |
| # samples | 2 | 2 | |
| ** MAII score | log2(2/4*10)=2.32192809488736 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: UTY [Title/Abstract] AND OTUD7A [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | OTUD7A | GO:0035871 | protein K11-linked deubiquitination | 23827681 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AI379977 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000331397 | ENST00000382902 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000331397 | ENST00000307050 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000382896 | ENST00000382902 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000382896 | ENST00000307050 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000537580 | ENST00000382902 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000537580 | ENST00000307050 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000362096 | ENST00000382902 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000362096 | ENST00000307050 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000329134 | ENST00000382902 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000329134 | ENST00000307050 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000538878 | ENST00000382902 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000538878 | ENST00000307050 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000540140 | ENST00000382902 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000540140 | ENST00000307050 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000545955 | ENST00000382902 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000545955 | ENST00000307050 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000474365 | ENST00000382902 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000474365 | ENST00000307050 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000382893 | ENST00000382902 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
| intron-intron | ENST00000382893 | ENST00000307050 | UTY | chrY | 15359375 | + | OTUD7A | chr15 | 32005592 | - |
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FusionProtFeatures for UTY_OTUD7A |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| UTY | OTUD7A |