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Fusion gene ID: 40950 |
FusionGeneSummary for USO1_SECISBP2L |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: USO1_SECISBP2L | Fusion gene ID: 40950 | Hgene | Tgene | Gene symbol | USO1 | SECISBP2L | Gene ID | 8615 | 9728 |
| Gene name | USO1 vesicle transport factor | SECIS binding protein 2 like | |
| Synonyms | P115|TAP|VDP | SBP2L|SLAN | |
| Cytomap | 4q21.1 | 15q21.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | general vesicular transport factor p115USO1 vesicle docking protein homologtranscytosis associated proteinvesicle docking protein p115 | selenocysteine insertion sequence-binding protein 2-like | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | O60763 | Q93073 | |
| Ensembl transtripts involved in fusion gene | ENST00000538159, ENST00000514213, | ENST00000559471, ENST00000261847, ENST00000559122, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 2 X 2 X 1=4 |
| # samples | 1 | 2 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: USO1 [Title/Abstract] AND SECISBP2L [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | H20018 | USO1 | chr4 | 76735304 | - | SECISBP2L | chr15 | 49308802 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000538159 | ENST00000559471 | USO1 | chr4 | 76735304 | - | SECISBP2L | chr15 | 49308802 | + |
| intron-3CDS | ENST00000538159 | ENST00000261847 | USO1 | chr4 | 76735304 | - | SECISBP2L | chr15 | 49308802 | + |
| intron-intron | ENST00000538159 | ENST00000559122 | USO1 | chr4 | 76735304 | - | SECISBP2L | chr15 | 49308802 | + |
| intron-3CDS | ENST00000514213 | ENST00000559471 | USO1 | chr4 | 76735304 | - | SECISBP2L | chr15 | 49308802 | + |
| intron-3CDS | ENST00000514213 | ENST00000261847 | USO1 | chr4 | 76735304 | - | SECISBP2L | chr15 | 49308802 | + |
| intron-intron | ENST00000514213 | ENST00000559122 | USO1 | chr4 | 76735304 | - | SECISBP2L | chr15 | 49308802 | + |
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FusionProtFeatures for USO1_SECISBP2L |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| USO1 | SECISBP2L |