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Fusion gene ID: 40708 |
FusionGeneSummary for UGGT2_ANKRD16 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: UGGT2_ANKRD16 | Fusion gene ID: 40708 | Hgene | Tgene | Gene symbol | UGGT2 | ANKRD16 | Gene ID | 55757 | 54522 |
| Gene name | UDP-glucose glycoprotein glucosyltransferase 2 | ankyrin repeat domain 16 | |
| Synonyms | HUGT2|UGCGL2|UGT2 | - | |
| Cytomap | 13q32.1 | 10p15.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | UDP-glucose:glycoprotein glucosyltransferase 2UDP-Glc:glycoprotein glucosyltransferase 2UDP-glucose ceramide glucosyltransferase-like 1UDP-glucose ceramide glucosyltransferase-like 2 | ankyrin repeat domain-containing protein 16 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q9NYU1 | Q6P6B7 | |
| Ensembl transtripts involved in fusion gene | ENST00000376747, ENST00000376714, ENST00000397618, ENST00000467305, ENST00000376712, | ENST00000380094, ENST00000380092, ENST00000191063, | |
| Fusion gene scores | * DoF score | 6 X 6 X 4=144 | 2 X 1 X 1=2 |
| # samples | 6 | 2 | |
| ** MAII score | log2(6/144*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/2*10)=3.32192809488736 | |
| Context | PubMed: UGGT2 [Title/Abstract] AND ANKRD16 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-EJ-5521-01A | UGGT2 | chr13 | 96705409 | - | ANKRD16 | chr10 | 5904654 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-3UTR | ENST00000376747 | ENST00000380094 | UGGT2 | chr13 | 96705409 | - | ANKRD16 | chr10 | 5904654 | - |
| 5CDS-intron | ENST00000376747 | ENST00000380092 | UGGT2 | chr13 | 96705409 | - | ANKRD16 | chr10 | 5904654 | - |
| 5CDS-intron | ENST00000376747 | ENST00000191063 | UGGT2 | chr13 | 96705409 | - | ANKRD16 | chr10 | 5904654 | - |
| 5CDS-3UTR | ENST00000376714 | ENST00000380094 | UGGT2 | chr13 | 96705409 | - | ANKRD16 | chr10 | 5904654 | - |
| 5CDS-intron | ENST00000376714 | ENST00000380092 | UGGT2 | chr13 | 96705409 | - | ANKRD16 | chr10 | 5904654 | - |
| 5CDS-intron | ENST00000376714 | ENST00000191063 | UGGT2 | chr13 | 96705409 | - | ANKRD16 | chr10 | 5904654 | - |
| 5CDS-3UTR | ENST00000397618 | ENST00000380094 | UGGT2 | chr13 | 96705409 | - | ANKRD16 | chr10 | 5904654 | - |
| 5CDS-intron | ENST00000397618 | ENST00000380092 | UGGT2 | chr13 | 96705409 | - | ANKRD16 | chr10 | 5904654 | - |
| 5CDS-intron | ENST00000397618 | ENST00000191063 | UGGT2 | chr13 | 96705409 | - | ANKRD16 | chr10 | 5904654 | - |
| intron-3UTR | ENST00000467305 | ENST00000380094 | UGGT2 | chr13 | 96705409 | - | ANKRD16 | chr10 | 5904654 | - |
| intron-intron | ENST00000467305 | ENST00000380092 | UGGT2 | chr13 | 96705409 | - | ANKRD16 | chr10 | 5904654 | - |
| intron-intron | ENST00000467305 | ENST00000191063 | UGGT2 | chr13 | 96705409 | - | ANKRD16 | chr10 | 5904654 | - |
| 5CDS-3UTR | ENST00000376712 | ENST00000380094 | UGGT2 | chr13 | 96705409 | - | ANKRD16 | chr10 | 5904654 | - |
| 5CDS-intron | ENST00000376712 | ENST00000380092 | UGGT2 | chr13 | 96705409 | - | ANKRD16 | chr10 | 5904654 | - |
| 5CDS-intron | ENST00000376712 | ENST00000191063 | UGGT2 | chr13 | 96705409 | - | ANKRD16 | chr10 | 5904654 | - |
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FusionProtFeatures for UGGT2_ANKRD16 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| UGGT2 | ANKRD16 |