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Fusion gene ID: 40700 |
FusionGeneSummary for UGDH-AS1_RNF121 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: UGDH-AS1_RNF121 | Fusion gene ID: 40700 | Hgene | Tgene | Gene symbol | UGDH-AS1 | RNF121 | Gene ID | 100885776 | 55298 |
| Gene name | UGDH antisense RNA 1 | ring finger protein 121 | |
| Synonyms | - | - | |
| Cytomap | 4p14 | 11q13.4 | |
| Type of gene | ncRNA | protein-coding | |
| Description | UGDH antisense RNA 1 (non-protein coding) | RING finger protein 121 | |
| Modification date | 20180329 | 20180523 | |
| UniProtAcc | Q9H920 | ||
| Ensembl transtripts involved in fusion gene | ENST00000504032, | ENST00000361756, ENST00000533380, ENST00000393713, ENST00000490867, ENST00000545854, ENST00000530137, | |
| Fusion gene scores | * DoF score | 2 X 2 X 1=4 | 5 X 5 X 3=75 |
| # samples | 3 | 6 | |
| ** MAII score | log2(3/4*10)=2.90689059560852 | log2(6/75*10)=-0.321928094887362 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: UGDH-AS1 [Title/Abstract] AND RNF121 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AI005126 | UGDH-AS1 | chr4 | 39590738 | + | RNF121 | chr11 | 71695361 | - | ||
| ChiTaRS3.1 | AI239943 | UGDH-AS1 | chr4 | 39590738 | + | RNF121 | chr11 | 71695361 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000504032 | ENST00000361756 | UGDH-AS1 | chr4 | 39590738 | + | RNF121 | chr11 | 71695361 | - |
| intron-intron | ENST00000504032 | ENST00000533380 | UGDH-AS1 | chr4 | 39590738 | + | RNF121 | chr11 | 71695361 | - |
| intron-intron | ENST00000504032 | ENST00000393713 | UGDH-AS1 | chr4 | 39590738 | + | RNF121 | chr11 | 71695361 | - |
| intron-intron | ENST00000504032 | ENST00000490867 | UGDH-AS1 | chr4 | 39590738 | + | RNF121 | chr11 | 71695361 | - |
| intron-intron | ENST00000504032 | ENST00000545854 | UGDH-AS1 | chr4 | 39590738 | + | RNF121 | chr11 | 71695361 | - |
| intron-intron | ENST00000504032 | ENST00000530137 | UGDH-AS1 | chr4 | 39590738 | + | RNF121 | chr11 | 71695361 | - |
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FusionProtFeatures for UGDH-AS1_RNF121 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| UGDH-AS1 | RNF121 |