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Fusion gene ID: 40205 |
FusionGeneSummary for TXNDC9_MLEC |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TXNDC9_MLEC | Fusion gene ID: 40205 | Hgene | Tgene | Gene symbol | TXNDC9 | MLEC | Gene ID | 10190 | 9761 |
| Gene name | thioredoxin domain containing 9 | malectin | |
| Synonyms | APACD|PHLP3 | KIAA0152 | |
| Cytomap | 2q11.2 | 12q24.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | thioredoxin domain-containing protein 9ATP binding protein associated with cell differentiationprotein 1-4 | malectinoligosaccharyltransferase complex subunit (non-catalytic) | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | O14530 | Q14165 | |
| Ensembl transtripts involved in fusion gene | ENST00000264255, ENST00000409434, ENST00000434323, ENST00000477337, | ENST00000228506, ENST00000412616, ENST00000535413, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 5 X 6 X 1=30 |
| # samples | 1 | 11 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(11/30*10)=1.87446911791614 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: TXNDC9 [Title/Abstract] AND MLEC [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AI651406 | TXNDC9 | chr2 | 99953945 | - | MLEC | chr12 | 121137195 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3UTR | ENST00000264255 | ENST00000228506 | TXNDC9 | chr2 | 99953945 | - | MLEC | chr12 | 121137195 | - |
| intron-intron | ENST00000264255 | ENST00000412616 | TXNDC9 | chr2 | 99953945 | - | MLEC | chr12 | 121137195 | - |
| intron-intron | ENST00000264255 | ENST00000535413 | TXNDC9 | chr2 | 99953945 | - | MLEC | chr12 | 121137195 | - |
| intron-3UTR | ENST00000409434 | ENST00000228506 | TXNDC9 | chr2 | 99953945 | - | MLEC | chr12 | 121137195 | - |
| intron-intron | ENST00000409434 | ENST00000412616 | TXNDC9 | chr2 | 99953945 | - | MLEC | chr12 | 121137195 | - |
| intron-intron | ENST00000409434 | ENST00000535413 | TXNDC9 | chr2 | 99953945 | - | MLEC | chr12 | 121137195 | - |
| intron-3UTR | ENST00000434323 | ENST00000228506 | TXNDC9 | chr2 | 99953945 | - | MLEC | chr12 | 121137195 | - |
| intron-intron | ENST00000434323 | ENST00000412616 | TXNDC9 | chr2 | 99953945 | - | MLEC | chr12 | 121137195 | - |
| intron-intron | ENST00000434323 | ENST00000535413 | TXNDC9 | chr2 | 99953945 | - | MLEC | chr12 | 121137195 | - |
| intron-3UTR | ENST00000477337 | ENST00000228506 | TXNDC9 | chr2 | 99953945 | - | MLEC | chr12 | 121137195 | - |
| intron-intron | ENST00000477337 | ENST00000412616 | TXNDC9 | chr2 | 99953945 | - | MLEC | chr12 | 121137195 | - |
| intron-intron | ENST00000477337 | ENST00000535413 | TXNDC9 | chr2 | 99953945 | - | MLEC | chr12 | 121137195 | - |
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FusionProtFeatures for TXNDC9_MLEC |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TXNDC9 | MLEC |