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Fusion gene ID: 40106 |
FusionGeneSummary for TUBBP5_SPRR4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TUBBP5_SPRR4 | Fusion gene ID: 40106 | Hgene | Tgene | Gene symbol | TUBBP5 | SPRR4 | Gene ID | 643224 | 163778 |
| Gene name | tubulin beta pseudogene 5 | small proline rich protein 4 | |
| Synonyms | - | - | |
| Cytomap | 9q34.3 | 1q21.3 | |
| Type of gene | pseudo | protein-coding | |
| Description | HSA9q34 beta-tubulin 4Q (TUBB4Q) pseudogenetubulin, beta 8 pseudogenetubulin, beta polypeptide pseudogene 5 | small proline-rich protein 4 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q96PI1 | ||
| Ensembl transtripts involved in fusion gene | ENST00000503395, | ENST00000328051, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 2 X 1 X 2=4 |
| # samples | 1 | 2 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: TUBBP5 [Title/Abstract] AND SPRR4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LUSC | TCGA-43-A56U-01A | TUBBP5 | chr9 | 141044760 | + | SPRR4 | chr1 | 152944347 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-5UTR | ENST00000503395 | ENST00000328051 | TUBBP5 | chr9 | 141044760 | + | SPRR4 | chr1 | 152944347 | + |
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FusionProtFeatures for TUBBP5_SPRR4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TUBBP5 | SPRR4 |