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Fusion gene ID: 39011 |
FusionGeneSummary for TNS3_ALG13 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TNS3_ALG13 | Fusion gene ID: 39011 | Hgene | Tgene | Gene symbol | TNS3 | ALG13 | Gene ID | 64759 | 79868 |
| Gene name | tensin 3 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | |
| Synonyms | TEM6|TENS1 | CDG1S|CXorf45|EIEE36|GLT28D1|MDS031|TDRD13|YGL047W | |
| Cytomap | 7p12.3 | Xq23 | |
| Type of gene | protein-coding | protein-coding | |
| Description | tensin-3tensin-like SH2 domain containing 1tensin-like SH2 domain-containing protein 1thyroid specific PTB domain proteintumor endothelial marker 6 | putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferaseUDP-N-acetylglucosamine transferase subunit ALG13 homologasparagine-linked glycosylation 13 homologg | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q68CZ2 | Q9NP73 | |
| Ensembl transtripts involved in fusion gene | ENST00000311160, ENST00000355730, ENST00000398879, ENST00000442536, ENST00000458317, ENST00000474346, | ENST00000371979, ENST00000251943, ENST00000394780, ENST00000470971, | |
| Fusion gene scores | * DoF score | 15 X 13 X 9=1755 | 2 X 2 X 2=8 |
| # samples | 17 | 2 | |
| ** MAII score | log2(17/1755*10)=-3.36786437905422 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: TNS3 [Title/Abstract] AND ALG13 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-FX-A2QS-01A | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-3CDS | ENST00000311160 | ENST00000371979 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| 5UTR-5UTR | ENST00000311160 | ENST00000251943 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| 5UTR-5UTR | ENST00000311160 | ENST00000394780 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| 5UTR-intron | ENST00000311160 | ENST00000470971 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| intron-3CDS | ENST00000355730 | ENST00000371979 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| intron-5UTR | ENST00000355730 | ENST00000251943 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| intron-5UTR | ENST00000355730 | ENST00000394780 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| intron-intron | ENST00000355730 | ENST00000470971 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| intron-3CDS | ENST00000398879 | ENST00000371979 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| intron-5UTR | ENST00000398879 | ENST00000251943 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| intron-5UTR | ENST00000398879 | ENST00000394780 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| intron-intron | ENST00000398879 | ENST00000470971 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| intron-3CDS | ENST00000442536 | ENST00000371979 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| intron-5UTR | ENST00000442536 | ENST00000251943 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| intron-5UTR | ENST00000442536 | ENST00000394780 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| intron-intron | ENST00000442536 | ENST00000470971 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| intron-3CDS | ENST00000458317 | ENST00000371979 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| intron-5UTR | ENST00000458317 | ENST00000251943 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| intron-5UTR | ENST00000458317 | ENST00000394780 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| intron-intron | ENST00000458317 | ENST00000470971 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| 5UTR-3CDS | ENST00000474346 | ENST00000371979 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| 5UTR-5UTR | ENST00000474346 | ENST00000251943 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| 5UTR-5UTR | ENST00000474346 | ENST00000394780 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
| 5UTR-intron | ENST00000474346 | ENST00000470971 | TNS3 | chr7 | 47621649 | - | ALG13 | chrX | 110925360 | + |
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FusionProtFeatures for TNS3_ALG13 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TNS3 | ALG13 |