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Fusion gene ID: 38966 |
FusionGeneSummary for TNRC18_TSGA13 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TNRC18_TSGA13 | Fusion gene ID: 38966 | Hgene | Tgene | Gene symbol | TNRC18 | TSGA13 | Gene ID | 84629 | 114960 |
| Gene name | trinucleotide repeat containing 18 | testis specific 13 | |
| Synonyms | CAGL79|TNRC18A | - | |
| Cytomap | 7p22.1 | 7q32.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | trinucleotide repeat-containing gene 18 proteinlong CAG trinucleotide repeat-containing gene 79 protein | testis-specific gene 13 proteintestis-specific A13 | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | O15417 | Q96PP4 | |
| Ensembl transtripts involved in fusion gene | ENST00000399537, ENST00000430969, ENST00000399434, | ENST00000456951, ENST00000356588, | |
| Fusion gene scores | * DoF score | 16 X 15 X 8=1920 | 1 X 1 X 1=1 |
| # samples | 25 | 1 | |
| ** MAII score | log2(25/1920*10)=-2.94110631094643 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: TNRC18 [Title/Abstract] AND TSGA13 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SKCM | TCGA-FS-A1ZY-06A | TNRC18 | chr7 | 5413686 | - | TSGA13 | chr7 | 130356628 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000399537 | ENST00000456951 | TNRC18 | chr7 | 5413686 | - | TSGA13 | chr7 | 130356628 | - |
| Frame-shift | ENST00000399537 | ENST00000356588 | TNRC18 | chr7 | 5413686 | - | TSGA13 | chr7 | 130356628 | - |
| Frame-shift | ENST00000430969 | ENST00000456951 | TNRC18 | chr7 | 5413686 | - | TSGA13 | chr7 | 130356628 | - |
| Frame-shift | ENST00000430969 | ENST00000356588 | TNRC18 | chr7 | 5413686 | - | TSGA13 | chr7 | 130356628 | - |
| intron-3CDS | ENST00000399434 | ENST00000456951 | TNRC18 | chr7 | 5413686 | - | TSGA13 | chr7 | 130356628 | - |
| intron-3CDS | ENST00000399434 | ENST00000356588 | TNRC18 | chr7 | 5413686 | - | TSGA13 | chr7 | 130356628 | - |
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FusionProtFeatures for TNRC18_TSGA13 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TNRC18 | TSGA13 |