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Fusion gene ID: 38875 |
FusionGeneSummary for TNFSF13B_RAB20 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TNFSF13B_RAB20 | Fusion gene ID: 38875 | Hgene | Tgene | Gene symbol | TNFSF13B | RAB20 | Gene ID | 10673 | 55647 |
| Gene name | TNF superfamily member 13b | RAB20, member RAS oncogene family | |
| Synonyms | BAFF|BLYS|CD257|DTL|TALL-1|TALL1|THANK|TNFSF20|TNLG7A|ZTNF4 | - | |
| Cytomap | 13q33.3 | 13q34 | |
| Type of gene | protein-coding | protein-coding | |
| Description | tumor necrosis factor ligand superfamily member 13BApoL related ligand TALL-1B-cell-activating factorB-lymphocyte stimulatorDelta4 BAFFTNF and ApoL-related leukocyte expressed ligand 1TNF homolog that activates apoptosisdelta BAFFdendritic cell-de | ras-related protein Rab-20 | |
| Modification date | 20180520 | 20180523 | |
| UniProtAcc | Q9Y275 | Q9NX57 | |
| Ensembl transtripts involved in fusion gene | ENST00000430559, ENST00000375887, ENST00000542136, ENST00000479435, | ENST00000267328, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 3 X 1 X 3=9 |
| # samples | 1 | 3 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: TNFSF13B [Title/Abstract] AND RAB20 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | COAD | TCGA-DM-A1D7-01A | TNFSF13B | chr13 | 108922772 | + | RAB20 | chr13 | 111176544 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000430559 | ENST00000267328 | TNFSF13B | chr13 | 108922772 | + | RAB20 | chr13 | 111176544 | - |
| In-frame | ENST00000375887 | ENST00000267328 | TNFSF13B | chr13 | 108922772 | + | RAB20 | chr13 | 111176544 | - |
| In-frame | ENST00000542136 | ENST00000267328 | TNFSF13B | chr13 | 108922772 | + | RAB20 | chr13 | 111176544 | - |
| 3UTR-3CDS | ENST00000479435 | ENST00000267328 | TNFSF13B | chr13 | 108922772 | + | RAB20 | chr13 | 111176544 | - |
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FusionProtFeatures for TNFSF13B_RAB20 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TNFSF13B | RAB20 |