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Fusion gene ID: 38587 |
FusionGeneSummary for TMEM255A_FPR2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TMEM255A_FPR2 | Fusion gene ID: 38587 | Hgene | Tgene | Gene symbol | TMEM255A | FPR2 | Gene ID | 55026 | 2358 |
| Gene name | transmembrane protein 255A | formyl peptide receptor 2 | |
| Synonyms | FAM70A | ALXR|FMLP-R-II|FMLPX|FPR2A|FPRH1|FPRH2|FPRL1|HM63|LXA4R | |
| Cytomap | Xq24 | 19q13.41 | |
| Type of gene | protein-coding | protein-coding | |
| Description | transmembrane protein 255Afamily with sequence similarity 70, member Aprotein FAM70A | N-formyl peptide receptor 2FMLP-R-IFMLP-related receptor ILXA4 receptorRFPformyl peptide receptor-like 1lipoxin A4 receptor (formyl peptide receptor related) | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q5JRV8 | P25090 | |
| Ensembl transtripts involved in fusion gene | ENST00000309720, ENST00000371369, ENST00000371352, ENST00000440464, ENST00000480821, | ENST00000340023, ENST00000598953, ENST00000598776, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 3 X 2 X 2=12 |
| # samples | 1 | 2 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(2/12*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: TMEM255A [Title/Abstract] AND FPR2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | FPR2 | GO:1904646 | cellular response to amyloid-beta | 11316806 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-FX-A2QS-01A | TMEM255A | chrX | 119438204 | - | FPR2 | chr19 | 52263285 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000309720 | ENST00000340023 | TMEM255A | chrX | 119438204 | - | FPR2 | chr19 | 52263285 | + |
| 5CDS-intron | ENST00000309720 | ENST00000598953 | TMEM255A | chrX | 119438204 | - | FPR2 | chr19 | 52263285 | + |
| 5CDS-intron | ENST00000309720 | ENST00000598776 | TMEM255A | chrX | 119438204 | - | FPR2 | chr19 | 52263285 | + |
| 5CDS-intron | ENST00000371369 | ENST00000340023 | TMEM255A | chrX | 119438204 | - | FPR2 | chr19 | 52263285 | + |
| 5CDS-intron | ENST00000371369 | ENST00000598953 | TMEM255A | chrX | 119438204 | - | FPR2 | chr19 | 52263285 | + |
| 5CDS-intron | ENST00000371369 | ENST00000598776 | TMEM255A | chrX | 119438204 | - | FPR2 | chr19 | 52263285 | + |
| intron-intron | ENST00000371352 | ENST00000340023 | TMEM255A | chrX | 119438204 | - | FPR2 | chr19 | 52263285 | + |
| intron-intron | ENST00000371352 | ENST00000598953 | TMEM255A | chrX | 119438204 | - | FPR2 | chr19 | 52263285 | + |
| intron-intron | ENST00000371352 | ENST00000598776 | TMEM255A | chrX | 119438204 | - | FPR2 | chr19 | 52263285 | + |
| 5CDS-intron | ENST00000440464 | ENST00000340023 | TMEM255A | chrX | 119438204 | - | FPR2 | chr19 | 52263285 | + |
| 5CDS-intron | ENST00000440464 | ENST00000598953 | TMEM255A | chrX | 119438204 | - | FPR2 | chr19 | 52263285 | + |
| 5CDS-intron | ENST00000440464 | ENST00000598776 | TMEM255A | chrX | 119438204 | - | FPR2 | chr19 | 52263285 | + |
| intron-intron | ENST00000480821 | ENST00000340023 | TMEM255A | chrX | 119438204 | - | FPR2 | chr19 | 52263285 | + |
| intron-intron | ENST00000480821 | ENST00000598953 | TMEM255A | chrX | 119438204 | - | FPR2 | chr19 | 52263285 | + |
| intron-intron | ENST00000480821 | ENST00000598776 | TMEM255A | chrX | 119438204 | - | FPR2 | chr19 | 52263285 | + |
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FusionProtFeatures for TMEM255A_FPR2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TMEM255A | FPR2 |