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Fusion gene ID: 38523 |
FusionGeneSummary for TMEM192_TMEM184C |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TMEM192_TMEM184C | Fusion gene ID: 38523 | Hgene | Tgene | Gene symbol | TMEM192 | TMEM184C | Gene ID | 201931 | 55751 |
| Gene name | transmembrane protein 192 | transmembrane protein 184C | |
| Synonyms | - | TMEM34 | |
| Cytomap | 4q32.3 | 4q31.23 | |
| Type of gene | protein-coding | protein-coding | |
| Description | transmembrane protein 192 | transmembrane protein 184Ctransmembrane protein 34 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q8IY95 | Q9NVA4 | |
| Ensembl transtripts involved in fusion gene | ENST00000506087, ENST00000306480, | ENST00000296582, ENST00000508208, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 3 X 2 X 4=24 |
| # samples | 1 | 5 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(5/24*10)=1.05889368905357 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: TMEM192 [Title/Abstract] AND TMEM184C [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | GBM | TCGA-19-2620-01A | TMEM192 | chr4 | 166021780 | - | TMEM184C | chr4 | 148593018 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000506087 | ENST00000296582 | TMEM192 | chr4 | 166021780 | - | TMEM184C | chr4 | 148593018 | + |
| 5CDS-intron | ENST00000506087 | ENST00000508208 | TMEM192 | chr4 | 166021780 | - | TMEM184C | chr4 | 148593018 | + |
| 5CDS-intron | ENST00000306480 | ENST00000296582 | TMEM192 | chr4 | 166021780 | - | TMEM184C | chr4 | 148593018 | + |
| 5CDS-intron | ENST00000306480 | ENST00000508208 | TMEM192 | chr4 | 166021780 | - | TMEM184C | chr4 | 148593018 | + |
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FusionProtFeatures for TMEM192_TMEM184C |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TMEM192 | TMEM184C |