|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 3852 |
FusionGeneSummary for BAZ1A_MYO1E |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: BAZ1A_MYO1E | Fusion gene ID: 3852 | Hgene | Tgene | Gene symbol | BAZ1A | MYO1E | Gene ID | 11177 | 4643 |
| Gene name | bromodomain adjacent to zinc finger domain 1A | myosin IE | |
| Synonyms | ACF1|WALp1|WCRF180|hACF1 | FSGS6|HuncM-IC|MYO1C | |
| Cytomap | 14q13.1-q13.2 | 15q22.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | bromodomain adjacent to zinc finger domain protein 1AATP-dependent chromatin remodeling proteinATP-utilizing chromatin assembly and remodeling factor 1CHRAC subunit ACF1hWALp1williams syndrome transcription factor-related chromatin-remodeling factor | unconventional myosin-IeMYO1E variant proteinmyosin-ICunconventional myosin 1E | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q9NRL2 | Q12965 | |
| Ensembl transtripts involved in fusion gene | ENST00000358716, ENST00000382422, ENST00000360310, ENST00000553853, | ENST00000288235, ENST00000558814, | |
| Fusion gene scores | * DoF score | 5 X 4 X 3=60 | 4 X 5 X 3=60 |
| # samples | 5 | 5 | |
| ** MAII score | log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: BAZ1A [Title/Abstract] AND MYO1E [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | BAZ1A | GO:0006261 | DNA-dependent DNA replication | 12434153 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BE005282 | BAZ1A | chr14 | 35234114 | - | MYO1E | chr15 | 59515304 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000358716 | ENST00000288235 | BAZ1A | chr14 | 35234114 | - | MYO1E | chr15 | 59515304 | + |
| intron-5UTR | ENST00000358716 | ENST00000558814 | BAZ1A | chr14 | 35234114 | - | MYO1E | chr15 | 59515304 | + |
| intron-3CDS | ENST00000382422 | ENST00000288235 | BAZ1A | chr14 | 35234114 | - | MYO1E | chr15 | 59515304 | + |
| intron-5UTR | ENST00000382422 | ENST00000558814 | BAZ1A | chr14 | 35234114 | - | MYO1E | chr15 | 59515304 | + |
| intron-3CDS | ENST00000360310 | ENST00000288235 | BAZ1A | chr14 | 35234114 | - | MYO1E | chr15 | 59515304 | + |
| intron-5UTR | ENST00000360310 | ENST00000558814 | BAZ1A | chr14 | 35234114 | - | MYO1E | chr15 | 59515304 | + |
| intron-3CDS | ENST00000553853 | ENST00000288235 | BAZ1A | chr14 | 35234114 | - | MYO1E | chr15 | 59515304 | + |
| intron-5UTR | ENST00000553853 | ENST00000558814 | BAZ1A | chr14 | 35234114 | - | MYO1E | chr15 | 59515304 | + |
Top |
FusionProtFeatures for BAZ1A_MYO1E |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| BAZ1A | MYO1E |