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Fusion gene ID: 37895 |
FusionGeneSummary for TGFBI_CNPY3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TGFBI_CNPY3 | Fusion gene ID: 37895 | Hgene | Tgene | Gene symbol | TGFBI | CNPY3 | Gene ID | 7045 | 10695 |
| Gene name | transforming growth factor beta induced | canopy FGF signaling regulator 3 | |
| Synonyms | BIGH3|CDB1|CDG2|CDGG1|CSD|CSD1|CSD2|CSD3|EBMD|LCD1 | CAG4A|EIEE60|ERDA5|PRAT4A|TNRC5 | |
| Cytomap | 5q31.1 | 6p21.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | transforming growth factor-beta-induced protein ig-h3RGD-CAPRGD-containing collagen-associated proteinbeta ig-h3betaig-h3kerato-epithelintransforming growth factor beta-induced 68kDatransforming growth factor, beta-induced, 68kD | protein canopy homolog 3CAG repeat containingCTG repeat protein 4aexpanded repeat-domain protein CAG/CTG 5protein associated with TLR4protein associated with Toll-like receptor 4Atrinucleotide repeat-containing gene 5 protein | |
| Modification date | 20180527 | 20180523 | |
| UniProtAcc | Q15582 | Q9BT09 | |
| Ensembl transtripts involved in fusion gene | ENST00000442011, ENST00000305126, ENST00000508076, ENST00000504185, | ENST00000372836, ENST00000394142, | |
| Fusion gene scores | * DoF score | 9 X 8 X 4=288 | 2 X 2 X 1=4 |
| # samples | 10 | 2 | |
| ** MAII score | log2(10/288*10)=-1.52606881166759 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: TGFBI [Title/Abstract] AND CNPY3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AB209598 | TGFBI | chr5 | 135390878 | + | CNPY3 | chr6 | 42906903 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3UTR | ENST00000442011 | ENST00000372836 | TGFBI | chr5 | 135390878 | + | CNPY3 | chr6 | 42906903 | + |
| intron-3UTR | ENST00000442011 | ENST00000394142 | TGFBI | chr5 | 135390878 | + | CNPY3 | chr6 | 42906903 | + |
| intron-3UTR | ENST00000305126 | ENST00000372836 | TGFBI | chr5 | 135390878 | + | CNPY3 | chr6 | 42906903 | + |
| intron-3UTR | ENST00000305126 | ENST00000394142 | TGFBI | chr5 | 135390878 | + | CNPY3 | chr6 | 42906903 | + |
| intron-3UTR | ENST00000508076 | ENST00000372836 | TGFBI | chr5 | 135390878 | + | CNPY3 | chr6 | 42906903 | + |
| intron-3UTR | ENST00000508076 | ENST00000394142 | TGFBI | chr5 | 135390878 | + | CNPY3 | chr6 | 42906903 | + |
| intron-3UTR | ENST00000504185 | ENST00000372836 | TGFBI | chr5 | 135390878 | + | CNPY3 | chr6 | 42906903 | + |
| intron-3UTR | ENST00000504185 | ENST00000394142 | TGFBI | chr5 | 135390878 | + | CNPY3 | chr6 | 42906903 | + |
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FusionProtFeatures for TGFBI_CNPY3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TGFBI | CNPY3 |