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Fusion gene ID: 3782 |
FusionGeneSummary for BACH2_BIVM |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: BACH2_BIVM | Fusion gene ID: 3782 | Hgene | Tgene | Gene symbol | BACH2 | BIVM | Gene ID | 60468 | 54841 |
| Gene name | BTB domain and CNC homolog 2 | basic, immunoglobulin-like variable motif containing | |
| Synonyms | BTBD25 | - | |
| Cytomap | 6q15 | 13q33.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | transcription regulator protein BACH2BTB and CNC homolog 2BTB and CNC homology 1, basic leucine zipper transcription factor 2 | basic immunoglobulin-like variable motif-containing protein | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q9BYV9 | Q86UB2 | |
| Ensembl transtripts involved in fusion gene | ENST00000257749, ENST00000537989, ENST00000343122, ENST00000470301, | ENST00000257336, ENST00000448849, ENST00000419638, ENST00000491929, | |
| Fusion gene scores | * DoF score | 3 X 2 X 3=18 | 1 X 1 X 1=1 |
| # samples | 3 | 1 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: BACH2 [Title/Abstract] AND BIVM [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-X6-A8C2-01A | BACH2 | chr6 | 90916288 | - | BIVM | chr13 | 103468778 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-3CDS | ENST00000257749 | ENST00000257336 | BACH2 | chr6 | 90916288 | - | BIVM | chr13 | 103468778 | + |
| 5UTR-5UTR | ENST00000257749 | ENST00000448849 | BACH2 | chr6 | 90916288 | - | BIVM | chr13 | 103468778 | + |
| 5UTR-5UTR | ENST00000257749 | ENST00000419638 | BACH2 | chr6 | 90916288 | - | BIVM | chr13 | 103468778 | + |
| 5UTR-intron | ENST00000257749 | ENST00000491929 | BACH2 | chr6 | 90916288 | - | BIVM | chr13 | 103468778 | + |
| 5UTR-3CDS | ENST00000537989 | ENST00000257336 | BACH2 | chr6 | 90916288 | - | BIVM | chr13 | 103468778 | + |
| 5UTR-5UTR | ENST00000537989 | ENST00000448849 | BACH2 | chr6 | 90916288 | - | BIVM | chr13 | 103468778 | + |
| 5UTR-5UTR | ENST00000537989 | ENST00000419638 | BACH2 | chr6 | 90916288 | - | BIVM | chr13 | 103468778 | + |
| 5UTR-intron | ENST00000537989 | ENST00000491929 | BACH2 | chr6 | 90916288 | - | BIVM | chr13 | 103468778 | + |
| 5UTR-3CDS | ENST00000343122 | ENST00000257336 | BACH2 | chr6 | 90916288 | - | BIVM | chr13 | 103468778 | + |
| 5UTR-5UTR | ENST00000343122 | ENST00000448849 | BACH2 | chr6 | 90916288 | - | BIVM | chr13 | 103468778 | + |
| 5UTR-5UTR | ENST00000343122 | ENST00000419638 | BACH2 | chr6 | 90916288 | - | BIVM | chr13 | 103468778 | + |
| 5UTR-intron | ENST00000343122 | ENST00000491929 | BACH2 | chr6 | 90916288 | - | BIVM | chr13 | 103468778 | + |
| 5UTR-3CDS | ENST00000470301 | ENST00000257336 | BACH2 | chr6 | 90916288 | - | BIVM | chr13 | 103468778 | + |
| 5UTR-5UTR | ENST00000470301 | ENST00000448849 | BACH2 | chr6 | 90916288 | - | BIVM | chr13 | 103468778 | + |
| 5UTR-5UTR | ENST00000470301 | ENST00000419638 | BACH2 | chr6 | 90916288 | - | BIVM | chr13 | 103468778 | + |
| 5UTR-intron | ENST00000470301 | ENST00000491929 | BACH2 | chr6 | 90916288 | - | BIVM | chr13 | 103468778 | + |
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FusionProtFeatures for BACH2_BIVM |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| BACH2 | BIVM |