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Fusion gene ID: 37758 |
FusionGeneSummary for TES_MBD2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TES_MBD2 | Fusion gene ID: 37758 | Hgene | Tgene | Gene symbol | TES | MBD2 | Gene ID | 26136 | 64174 |
| Gene name | testin LIM domain protein | dipeptidase 2 | |
| Synonyms | TESS|TESS-2 | MBD2 | |
| Cytomap | 7q31.2 | 16q22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | testintestis derived transcript (3 LIM domains) | dipeptidase 2 | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | Q9UGI8 | Q9UBB5 | |
| Ensembl transtripts involved in fusion gene | ENST00000358204, ENST00000537767, ENST00000393481, ENST00000485009, | ENST00000256429, ENST00000579025, ENST00000398398, ENST00000583046, | |
| Fusion gene scores | * DoF score | 4 X 4 X 2=32 | 4 X 4 X 2=32 |
| # samples | 4 | 4 | |
| ** MAII score | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: TES [Title/Abstract] AND MBD2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BF327648 | TES | chr7 | 115898585 | - | MBD2 | chr18 | 51737199 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-intron | ENST00000358204 | ENST00000256429 | TES | chr7 | 115898585 | - | MBD2 | chr18 | 51737199 | - |
| 3UTR-intron | ENST00000358204 | ENST00000579025 | TES | chr7 | 115898585 | - | MBD2 | chr18 | 51737199 | - |
| 3UTR-intron | ENST00000358204 | ENST00000398398 | TES | chr7 | 115898585 | - | MBD2 | chr18 | 51737199 | - |
| 3UTR-intron | ENST00000358204 | ENST00000583046 | TES | chr7 | 115898585 | - | MBD2 | chr18 | 51737199 | - |
| intron-intron | ENST00000537767 | ENST00000256429 | TES | chr7 | 115898585 | - | MBD2 | chr18 | 51737199 | - |
| intron-intron | ENST00000537767 | ENST00000579025 | TES | chr7 | 115898585 | - | MBD2 | chr18 | 51737199 | - |
| intron-intron | ENST00000537767 | ENST00000398398 | TES | chr7 | 115898585 | - | MBD2 | chr18 | 51737199 | - |
| intron-intron | ENST00000537767 | ENST00000583046 | TES | chr7 | 115898585 | - | MBD2 | chr18 | 51737199 | - |
| 3UTR-intron | ENST00000393481 | ENST00000256429 | TES | chr7 | 115898585 | - | MBD2 | chr18 | 51737199 | - |
| 3UTR-intron | ENST00000393481 | ENST00000579025 | TES | chr7 | 115898585 | - | MBD2 | chr18 | 51737199 | - |
| 3UTR-intron | ENST00000393481 | ENST00000398398 | TES | chr7 | 115898585 | - | MBD2 | chr18 | 51737199 | - |
| 3UTR-intron | ENST00000393481 | ENST00000583046 | TES | chr7 | 115898585 | - | MBD2 | chr18 | 51737199 | - |
| intron-intron | ENST00000485009 | ENST00000256429 | TES | chr7 | 115898585 | - | MBD2 | chr18 | 51737199 | - |
| intron-intron | ENST00000485009 | ENST00000579025 | TES | chr7 | 115898585 | - | MBD2 | chr18 | 51737199 | - |
| intron-intron | ENST00000485009 | ENST00000398398 | TES | chr7 | 115898585 | - | MBD2 | chr18 | 51737199 | - |
| intron-intron | ENST00000485009 | ENST00000583046 | TES | chr7 | 115898585 | - | MBD2 | chr18 | 51737199 | - |
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FusionProtFeatures for TES_MBD2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TES | MBD2 |