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Fusion gene ID: 37664 |
FusionGeneSummary for TDRD7_PRR16 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TDRD7_PRR16 | Fusion gene ID: 37664 | Hgene | Tgene | Gene symbol | TDRD7 | PRR16 | Gene ID | 23424 | 51334 |
| Gene name | tudor domain containing 7 | proline rich 16 | |
| Synonyms | CATC4|PCTAIRE2BP|TRAP | DSC54|LARGEN | |
| Cytomap | 9q22.33 | 5q23.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | tudor domain-containing protein 7PCTAIRE2-binding proteintudor repeat associator with PCTAIRE 2 | protein Largenmesenchymal stem cell protein DSC54proline-rich protein 16 | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q8NHU6 | Q569H4 | |
| Ensembl transtripts involved in fusion gene | ENST00000355295, ENST00000422139, ENST00000540902, ENST00000492428, | ENST00000407149, ENST00000379551, ENST00000505123, ENST00000446965, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 4 X 2 X 4=32 |
| # samples | 2 | 4 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: TDRD7 [Title/Abstract] AND PRR16 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | PRR16 | GO:0045727 | positive regulation of translation | 24656129 |
| Tgene | PRR16 | GO:0045793 | positive regulation of cell size | 24656129 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BG117378 | TDRD7 | chr9 | 100255175 | - | PRR16 | chr5 | 120022337 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000355295 | ENST00000407149 | TDRD7 | chr9 | 100255175 | - | PRR16 | chr5 | 120022337 | + |
| intron-3CDS | ENST00000355295 | ENST00000379551 | TDRD7 | chr9 | 100255175 | - | PRR16 | chr5 | 120022337 | + |
| intron-3CDS | ENST00000355295 | ENST00000505123 | TDRD7 | chr9 | 100255175 | - | PRR16 | chr5 | 120022337 | + |
| intron-3CDS | ENST00000355295 | ENST00000446965 | TDRD7 | chr9 | 100255175 | - | PRR16 | chr5 | 120022337 | + |
| intron-3CDS | ENST00000422139 | ENST00000407149 | TDRD7 | chr9 | 100255175 | - | PRR16 | chr5 | 120022337 | + |
| intron-3CDS | ENST00000422139 | ENST00000379551 | TDRD7 | chr9 | 100255175 | - | PRR16 | chr5 | 120022337 | + |
| intron-3CDS | ENST00000422139 | ENST00000505123 | TDRD7 | chr9 | 100255175 | - | PRR16 | chr5 | 120022337 | + |
| intron-3CDS | ENST00000422139 | ENST00000446965 | TDRD7 | chr9 | 100255175 | - | PRR16 | chr5 | 120022337 | + |
| intron-3CDS | ENST00000540902 | ENST00000407149 | TDRD7 | chr9 | 100255175 | - | PRR16 | chr5 | 120022337 | + |
| intron-3CDS | ENST00000540902 | ENST00000379551 | TDRD7 | chr9 | 100255175 | - | PRR16 | chr5 | 120022337 | + |
| intron-3CDS | ENST00000540902 | ENST00000505123 | TDRD7 | chr9 | 100255175 | - | PRR16 | chr5 | 120022337 | + |
| intron-3CDS | ENST00000540902 | ENST00000446965 | TDRD7 | chr9 | 100255175 | - | PRR16 | chr5 | 120022337 | + |
| intron-3CDS | ENST00000492428 | ENST00000407149 | TDRD7 | chr9 | 100255175 | - | PRR16 | chr5 | 120022337 | + |
| intron-3CDS | ENST00000492428 | ENST00000379551 | TDRD7 | chr9 | 100255175 | - | PRR16 | chr5 | 120022337 | + |
| intron-3CDS | ENST00000492428 | ENST00000505123 | TDRD7 | chr9 | 100255175 | - | PRR16 | chr5 | 120022337 | + |
| intron-3CDS | ENST00000492428 | ENST00000446965 | TDRD7 | chr9 | 100255175 | - | PRR16 | chr5 | 120022337 | + |
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FusionProtFeatures for TDRD7_PRR16 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TDRD7 | PRR16 |