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Fusion gene ID: 3751 |
FusionGeneSummary for B4GALT5_PTK7 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: B4GALT5_PTK7 | Fusion gene ID: 3751 | Hgene | Tgene | Gene symbol | B4GALT5 | PTK7 | Gene ID | 9334 | 5754 |
| Gene name | beta-1,4-galactosyltransferase 5 | protein tyrosine kinase 7 (inactive) | |
| Synonyms | B4Gal-T5|BETA4-GALT-IV|beta4Gal-T5|beta4GalT-V|gt-V | CCK-4|CCK4 | |
| Cytomap | 20q13.13 | 6p21.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | beta-1,4-galactosyltransferase 5UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5beta-1,4-GalT IIbeta-1,4-GalT I | inactive tyrosine-protein kinase 7PTK7 protein tyrosine kinase 7colon carcinoma kinase 4pseudo tyrosine kinase receptor 7tyrosine-protein kinase-like 7 | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | O43286 | Q13308 | |
| Ensembl transtripts involved in fusion gene | ENST00000371711, | ENST00000230419, ENST00000349241, ENST00000345201, ENST00000352931, ENST00000481273, ENST00000476760, ENST00000471863, | |
| Fusion gene scores | * DoF score | 14 X 9 X 9=1134 | 5 X 5 X 3=75 |
| # samples | 14 | 6 | |
| ** MAII score | log2(14/1134*10)=-3.01792190799726 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/75*10)=-0.321928094887362 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: B4GALT5 [Title/Abstract] AND PTK7 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BF812681 | B4GALT5 | chr20 | 48252621 | - | PTK7 | chr6 | 43113045 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000371711 | ENST00000230419 | B4GALT5 | chr20 | 48252621 | - | PTK7 | chr6 | 43113045 | + |
| intron-3CDS | ENST00000371711 | ENST00000349241 | B4GALT5 | chr20 | 48252621 | - | PTK7 | chr6 | 43113045 | + |
| intron-3CDS | ENST00000371711 | ENST00000345201 | B4GALT5 | chr20 | 48252621 | - | PTK7 | chr6 | 43113045 | + |
| intron-3CDS | ENST00000371711 | ENST00000352931 | B4GALT5 | chr20 | 48252621 | - | PTK7 | chr6 | 43113045 | + |
| intron-3CDS | ENST00000371711 | ENST00000481273 | B4GALT5 | chr20 | 48252621 | - | PTK7 | chr6 | 43113045 | + |
| intron-intron | ENST00000371711 | ENST00000476760 | B4GALT5 | chr20 | 48252621 | - | PTK7 | chr6 | 43113045 | + |
| intron-intron | ENST00000371711 | ENST00000471863 | B4GALT5 | chr20 | 48252621 | - | PTK7 | chr6 | 43113045 | + |
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FusionProtFeatures for B4GALT5_PTK7 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| B4GALT5 | PTK7 |