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Fusion gene ID: 37433 |
FusionGeneSummary for TBCB_B3GALNT1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TBCB_B3GALNT1 | Fusion gene ID: 37433 | Hgene | Tgene | Gene symbol | TBCB | B3GALNT1 | Gene ID | 1155 | 8706 |
| Gene name | tubulin folding cofactor B | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) | |
| Synonyms | CG22|CKAP1|CKAPI | B3GALT3|GLCT3|GLOB|Gb4Cer|P|P1|beta3Gal-T3|galT3 | |
| Cytomap | 19q13.12 | 3q26.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | tubulin-folding cofactor Bcytoskeleton associated protein 1cytoskeleton-associated protein CKAPItubulin-specific chaperone B | UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1P antigen synthaseP blood group globosideUDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 3 (Globoside blood group)UDP-GalNAc:betaGlcNAc beta-1,3-galactosaminyltransferase, polypepti | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q99426 | O75752 | |
| Ensembl transtripts involved in fusion gene | ENST00000221855, ENST00000392178, ENST00000589996, ENST00000585746, ENST00000586868, | ENST00000320474, ENST00000392779, ENST00000392780, ENST00000392781, ENST00000473285, ENST00000417187, ENST00000488170, ENST00000494818, | |
| Fusion gene scores | * DoF score | 5 X 5 X 3=75 | 1 X 1 X 1=1 |
| # samples | 5 | 1 | |
| ** MAII score | log2(5/75*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: TBCB [Title/Abstract] AND B3GALNT1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | DA235308 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000221855 | ENST00000320474 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| Frame-shift | ENST00000221855 | ENST00000392779 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| Frame-shift | ENST00000221855 | ENST00000392780 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| Frame-shift | ENST00000221855 | ENST00000392781 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| In-frame | ENST00000221855 | ENST00000473285 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| Frame-shift | ENST00000221855 | ENST00000417187 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| In-frame | ENST00000221855 | ENST00000488170 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| 5CDS-intron | ENST00000221855 | ENST00000494818 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| 3UTR-3CDS | ENST00000392178 | ENST00000320474 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| 3UTR-3CDS | ENST00000392178 | ENST00000392779 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| 3UTR-3CDS | ENST00000392178 | ENST00000392780 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| 3UTR-3CDS | ENST00000392178 | ENST00000392781 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| 3UTR-3CDS | ENST00000392178 | ENST00000473285 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| 3UTR-3CDS | ENST00000392178 | ENST00000417187 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| 3UTR-3CDS | ENST00000392178 | ENST00000488170 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| 3UTR-intron | ENST00000392178 | ENST00000494818 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| Frame-shift | ENST00000589996 | ENST00000320474 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| Frame-shift | ENST00000589996 | ENST00000392779 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| Frame-shift | ENST00000589996 | ENST00000392780 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| Frame-shift | ENST00000589996 | ENST00000392781 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| In-frame | ENST00000589996 | ENST00000473285 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| Frame-shift | ENST00000589996 | ENST00000417187 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| In-frame | ENST00000589996 | ENST00000488170 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| 5CDS-intron | ENST00000589996 | ENST00000494818 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| Frame-shift | ENST00000585746 | ENST00000320474 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| Frame-shift | ENST00000585746 | ENST00000392779 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| Frame-shift | ENST00000585746 | ENST00000392780 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| Frame-shift | ENST00000585746 | ENST00000392781 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| In-frame | ENST00000585746 | ENST00000473285 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| Frame-shift | ENST00000585746 | ENST00000417187 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| In-frame | ENST00000585746 | ENST00000488170 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| 5CDS-intron | ENST00000585746 | ENST00000494818 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| intron-3CDS | ENST00000586868 | ENST00000320474 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| intron-3CDS | ENST00000586868 | ENST00000392779 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| intron-3CDS | ENST00000586868 | ENST00000392780 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| intron-3CDS | ENST00000586868 | ENST00000392781 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| intron-3CDS | ENST00000586868 | ENST00000473285 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| intron-3CDS | ENST00000586868 | ENST00000417187 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| intron-3CDS | ENST00000586868 | ENST00000488170 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
| intron-intron | ENST00000586868 | ENST00000494818 | TBCB | chr19 | 36611637 | + | B3GALNT1 | chr3 | 160804539 | - |
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FusionProtFeatures for TBCB_B3GALNT1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TBCB | B3GALNT1 |