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Fusion gene ID: 37421 |
FusionGeneSummary for TBC1D9B_C5orf60 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TBC1D9B_C5orf60 | Fusion gene ID: 37421 | Hgene | Tgene | Gene symbol | TBC1D9B | C5orf60 | Gene ID | 23061 | 285679 |
| Gene name | TBC1 domain family member 9B | chromosome 5 open reading frame 60 | |
| Synonyms | GRAMD9B | - | |
| Cytomap | 5q35.3 | 5q35.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | TBC1 domain family member 9BTBC1 domain family, member 9B (with GRAM domain) | putative uncharacterized protein FLJ35723 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q66K14 | A6NFR6 | |
| Ensembl transtripts involved in fusion gene | ENST00000355235, ENST00000356834, ENST00000518085, ENST00000519746, ENST00000444477, | ENST00000448248, ENST00000506142, | |
| Fusion gene scores | * DoF score | 5 X 5 X 5=125 | 2 X 2 X 2=8 |
| # samples | 5 | 2 | |
| ** MAII score | log2(5/125*10)=-1.32192809488736 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: TBC1D9B [Title/Abstract] AND C5orf60 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BLCA | TCGA-FD-A3SJ-01A | TBC1D9B | chr5 | 179301902 | - | C5orf60 | chr5 | 179068879 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-3UTR | ENST00000355235 | ENST00000448248 | TBC1D9B | chr5 | 179301902 | - | C5orf60 | chr5 | 179068879 | - |
| 5CDS-intron | ENST00000355235 | ENST00000506142 | TBC1D9B | chr5 | 179301902 | - | C5orf60 | chr5 | 179068879 | - |
| 5CDS-3UTR | ENST00000356834 | ENST00000448248 | TBC1D9B | chr5 | 179301902 | - | C5orf60 | chr5 | 179068879 | - |
| 5CDS-intron | ENST00000356834 | ENST00000506142 | TBC1D9B | chr5 | 179301902 | - | C5orf60 | chr5 | 179068879 | - |
| intron-3UTR | ENST00000518085 | ENST00000448248 | TBC1D9B | chr5 | 179301902 | - | C5orf60 | chr5 | 179068879 | - |
| intron-intron | ENST00000518085 | ENST00000506142 | TBC1D9B | chr5 | 179301902 | - | C5orf60 | chr5 | 179068879 | - |
| intron-3UTR | ENST00000519746 | ENST00000448248 | TBC1D9B | chr5 | 179301902 | - | C5orf60 | chr5 | 179068879 | - |
| intron-intron | ENST00000519746 | ENST00000506142 | TBC1D9B | chr5 | 179301902 | - | C5orf60 | chr5 | 179068879 | - |
| intron-3UTR | ENST00000444477 | ENST00000448248 | TBC1D9B | chr5 | 179301902 | - | C5orf60 | chr5 | 179068879 | - |
| intron-intron | ENST00000444477 | ENST00000506142 | TBC1D9B | chr5 | 179301902 | - | C5orf60 | chr5 | 179068879 | - |
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FusionProtFeatures for TBC1D9B_C5orf60 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TBC1D9B | C5orf60 |