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Fusion gene ID: 37401 |
FusionGeneSummary for TBC1D32_CCDC162P |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TBC1D32_CCDC162P | Fusion gene ID: 37401 | Hgene | Tgene | Gene symbol | TBC1D32 | CCDC162P | Gene ID | 221322 | 221262 |
| Gene name | TBC1 domain family member 32 | coiled-coil domain containing 162, pseudogene | |
| Synonyms | BROMI|C6orf170|C6orf171|bA301B7.2|bA57L9.1|dJ310J6.1 | C6orf183|C6orf184|C6orf185|CCDC162 | |
| Cytomap | 6q22.31 | 6q21 | |
| Type of gene | protein-coding | pseudo | |
| Description | protein broad-mindedbA301B7.2 (novel protein)broad-minded homologdJ310J6.1 (novel protein) | - | |
| Modification date | 20180523 | 20180402 | |
| UniProtAcc | Q96NH3 | ||
| Ensembl transtripts involved in fusion gene | ENST00000275159, ENST00000398212, ENST00000398197, | ENST00000422819, | |
| Fusion gene scores | * DoF score | 3 X 2 X 2=12 | 5 X 5 X 3=75 |
| # samples | 3 | 5 | |
| ** MAII score | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(5/75*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: TBC1D32 [Title/Abstract] AND CCDC162P [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-E9-A248-01A | TBC1D32 | chr6 | 121600267 | - | CCDC162P | chr6 | 109505130 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000275159 | ENST00000422819 | TBC1D32 | chr6 | 121600267 | - | CCDC162P | chr6 | 109505130 | + |
| 5CDS-intron | ENST00000398212 | ENST00000422819 | TBC1D32 | chr6 | 121600267 | - | CCDC162P | chr6 | 109505130 | + |
| intron-intron | ENST00000398197 | ENST00000422819 | TBC1D32 | chr6 | 121600267 | - | CCDC162P | chr6 | 109505130 | + |
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FusionProtFeatures for TBC1D32_CCDC162P |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TBC1D32 | CCDC162P |