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Fusion gene ID: 37211 |
FusionGeneSummary for TAOK1_C17orf105 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TAOK1_C17orf105 | Fusion gene ID: 37211 | Hgene | Tgene | Gene symbol | TAOK1 | C17orf105 | Gene ID | 57551 |
| Gene name | TAO kinase 1 | ||
| Synonyms | KFC-B|MAP3K16|MARKK|PSK-2|PSK2|TAO1|hKFC-B|hTAOK1 | ||
| Cytomap | 17q11.2 | ||
| Type of gene | protein-coding | ||
| Description | serine/threonine-protein kinase TAO1MARK KinaseSTE20-like kinase PSK2kinase from chicken homolog Bmicrotubule affinity regulating kinase kinaseprostate-derived STE20-like kinase 2prostate-derived sterile 20-like kinase 2serine/threonine protein kin | ||
| Modification date | 20180523 | ||
| UniProtAcc | Q7L7X3 | ||
| Ensembl transtripts involved in fusion gene | ENST00000261716, ENST00000536202, | ENST00000449302, | |
| Fusion gene scores | * DoF score | 27 X 13 X 16=5616 | 1 X 2 X 1=2 |
| # samples | 28 | 1 | |
| ** MAII score | log2(28/5616*10)=-4.32604420335959 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/2*10)=2.32192809488736 | |
| Context | PubMed: TAOK1 [Title/Abstract] AND C17orf105 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Kinase involved fusion gene, inframe and retained kinase domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | TAOK1 | GO:0006974 | cellular response to DNA damage stimulus | 17396146 |
| Hgene | TAOK1 | GO:0046330 | positive regulation of JNK cascade | 16407310 |
| Hgene | TAOK1 | GO:0097194 | execution phase of apoptosis | 16407310 |