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Fusion gene ID: 37093 |
FusionGeneSummary for TAF1D_TRUB1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TAF1D_TRUB1 | Fusion gene ID: 37093 | Hgene | Tgene | Gene symbol | TAF1D | TRUB1 | Gene ID | 79101 | 142940 |
| Gene name | TATA-box binding protein associated factor, RNA polymerase I subunit D | TruB pseudouridine synthase family member 1 | |
| Synonyms | JOSD3|RAFI41|TAF(I)41|TAFI41 | PUS4 | |
| Cytomap | 11q21 | 10q25.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | TATA box-binding protein-associated factor RNA polymerase I subunit DJosephin domain containing 3RNA polymerase I-specific TBP-associated factor 41 kDaTATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDaTATA box-binding protein | probable tRNA pseudouridine synthase 1TruB pseudouridine (psi) synthase family member 1TruB pseudouridine (psi) synthase homolog 1 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9H5J8 | Q8WWH5 | |
| Ensembl transtripts involved in fusion gene | ENST00000546088, ENST00000448108, | ENST00000298746, ENST00000485065, | |
| Fusion gene scores | * DoF score | 8 X 9 X 2=144 | 2 X 2 X 2=8 |
| # samples | 8 | 2 | |
| ** MAII score | log2(8/144*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: TAF1D [Title/Abstract] AND TRUB1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BF801407 | TAF1D | chr11 | 93469337 | - | TRUB1 | chr10 | 116735549 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3UTR | ENST00000546088 | ENST00000298746 | TAF1D | chr11 | 93469337 | - | TRUB1 | chr10 | 116735549 | - |
| intron-intron | ENST00000546088 | ENST00000485065 | TAF1D | chr11 | 93469337 | - | TRUB1 | chr10 | 116735549 | - |
| intron-3UTR | ENST00000448108 | ENST00000298746 | TAF1D | chr11 | 93469337 | - | TRUB1 | chr10 | 116735549 | - |
| intron-intron | ENST00000448108 | ENST00000485065 | TAF1D | chr11 | 93469337 | - | TRUB1 | chr10 | 116735549 | - |
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FusionProtFeatures for TAF1D_TRUB1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TAF1D | TRUB1 |