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Fusion gene ID: 3706 |
FusionGeneSummary for B3GALTL_MTUS2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: B3GALTL_MTUS2 | Fusion gene ID: 3706 | Hgene | Tgene | Gene symbol | B3GALTL | MTUS2 | Gene ID | 145173 | 23281 |
| Gene name | beta 3-glucosyltransferase | microtubule associated scaffold protein 2 | |
| Synonyms | B3GALTL|B3GTL|B3Glc-T|Gal-T|beta3Glc-T | CAZIP|ICIS|KIAA0774|TIP150 | |
| Cytomap | 13q12.3 | 13q12.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | beta-1,3-glucosyltransferaseUDP-GAL:beta-GlcNAc beta-1,3-galactosyltransferase-likebeta 1,3-galactosyltransferase-likebeta 3-glycosyltransferase-like | microtubule-associated tumor suppressor candidate 2+TIP of 150 kDacardiac zipper proteinmicrotubule associated tumor suppressor candidate 2microtubule plus-end tracking protein TIP150tracking protein of 150 kDa | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q5JR59 | ||
| Ensembl transtripts involved in fusion gene | ENST00000343307, ENST00000461652, | ENST00000431530, ENST00000380808, ENST00000542829, ENST00000400542, | |
| Fusion gene scores | * DoF score | 3 X 2 X 2=12 | 6 X 5 X 2=60 |
| # samples | 3 | 6 | |
| ** MAII score | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(6/60*10)=0 | |
| Context | PubMed: B3GALTL [Title/Abstract] AND MTUS2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-BH-A0HB-01A | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000343307 | ENST00000431530 | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
| In-frame | ENST00000343307 | ENST00000380808 | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
| 5CDS-intron | ENST00000343307 | ENST00000542829 | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
| 5CDS-intron | ENST00000343307 | ENST00000400542 | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
| intron-3CDS | ENST00000461652 | ENST00000431530 | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
| intron-3CDS | ENST00000461652 | ENST00000380808 | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
| intron-intron | ENST00000461652 | ENST00000542829 | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
| intron-intron | ENST00000461652 | ENST00000400542 | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
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FusionProtFeatures for B3GALTL_MTUS2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| B3GALTL | MTUS2 |