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Fusion gene ID: 36895 |
FusionGeneSummary for SYN3_ZBTB24 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SYN3_ZBTB24 | Fusion gene ID: 36895 | Hgene | Tgene | Gene symbol | SYN3 | ZBTB24 | Gene ID | 8224 | 9841 |
| Gene name | synapsin III | zinc finger and BTB domain containing 24 | |
| Synonyms | - | BIF1|ICF2|PATZ2|ZNF450 | |
| Cytomap | 22q12.3 | 6q21 | |
| Type of gene | protein-coding | protein-coding | |
| Description | synapsin-3cN28H9.2 (synapsin III) | zinc finger and BTB domain-containing protein 24POZ (BTB) and AT hook containing zinc finger 2zinc finger protein 450 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | O14994 | O43167 | |
| Ensembl transtripts involved in fusion gene | ENST00000358763, ENST00000332840, ENST00000467095, | ENST00000230122, | |
| Fusion gene scores | * DoF score | 7 X 9 X 2=126 | 1 X 1 X 1=1 |
| # samples | 9 | 1 | |
| ** MAII score | log2(9/126*10)=-0.485426827170242 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: SYN3 [Title/Abstract] AND ZBTB24 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BQ344906 | SYN3 | chr22 | 33258806 | + | ZBTB24 | chr6 | 109802624 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000358763 | ENST00000230122 | SYN3 | chr22 | 33258806 | + | ZBTB24 | chr6 | 109802624 | + |
| intron-3CDS | ENST00000332840 | ENST00000230122 | SYN3 | chr22 | 33258806 | + | ZBTB24 | chr6 | 109802624 | + |
| intron-3CDS | ENST00000467095 | ENST00000230122 | SYN3 | chr22 | 33258806 | + | ZBTB24 | chr6 | 109802624 | + |
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FusionProtFeatures for SYN3_ZBTB24 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SYN3 | ZBTB24 |