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Fusion gene ID: 36363 |
FusionGeneSummary for STARD7_AARS |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: STARD7_AARS | Fusion gene ID: 36363 | Hgene | Tgene | Gene symbol | STARD7 | AARS | Gene ID | 56910 | 16 |
| Gene name | StAR related lipid transfer domain containing 7 | alanyl-tRNA synthetase | |
| Synonyms | GTT1 | CMT2N|EIEE29 | |
| Cytomap | 2q11.2 | 16q22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | stAR-related lipid transfer protein 7, mitochondrialSTART domain containing 7START domain-containing protein 7StAR-related lipid transfer (START) domain containing 7gestational trophoblastic tumor protein 1 | alanine--tRNA ligase, cytoplasmicalaRSalanine tRNA ligase 1, cytoplasmicalanyl-tRNA synthetase, cytoplasmicrenal carcinoma antigen NY-REN-42 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9NQZ5 | P49588 | |
| Ensembl transtripts involved in fusion gene | ENST00000337288, ENST00000462501, | ENST00000261772, ENST00000564359, | |
| Fusion gene scores | * DoF score | 7 X 7 X 3=147 | 7 X 6 X 4=168 |
| # samples | 7 | 7 | |
| ** MAII score | log2(7/147*10)=-1.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/168*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: STARD7 [Title/Abstract] AND AARS [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | AARS | GO:0006419 | alanyl-tRNA aminoacylation | 27622773|28493438 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BF810167 | STARD7 | chr2 | 96851310 | + | AARS | chr16 | 70290018 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000337288 | ENST00000261772 | STARD7 | chr2 | 96851310 | + | AARS | chr16 | 70290018 | + |
| intron-intron | ENST00000337288 | ENST00000564359 | STARD7 | chr2 | 96851310 | + | AARS | chr16 | 70290018 | + |
| intron-intron | ENST00000462501 | ENST00000261772 | STARD7 | chr2 | 96851310 | + | AARS | chr16 | 70290018 | + |
| intron-intron | ENST00000462501 | ENST00000564359 | STARD7 | chr2 | 96851310 | + | AARS | chr16 | 70290018 | + |
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FusionProtFeatures for STARD7_AARS |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| STARD7 | AARS |