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Fusion gene ID: 36332 |
FusionGeneSummary for STARD10_ZC3H12C |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: STARD10_ZC3H12C | Fusion gene ID: 36332 | Hgene | Tgene | Gene symbol | STARD10 | ZC3H12C | Gene ID | 10809 | 85463 |
| Gene name | StAR related lipid transfer domain containing 10 | zinc finger CCCH-type containing 12C | |
| Synonyms | CGI-52|NY-CO-28|PCTP2|SDCCAG28 | MCPIP3 | |
| Cytomap | 11q13.4 | 11q22.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | START domain-containing protein 10PCTP-LPCTP-like proteinSTART domain containing 10StAR-related lipid transfer (START) domain containing 10antigen NY-CO-28serologically defined colon cancer antigen 28stAR-related lipid transfer protein 10 | probable ribonuclease ZC3H12CMCP-induced protein 3zinc finger CCCH domain-containing protein 12C | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q9Y365 | Q9C0D7 | |
| Ensembl transtripts involved in fusion gene | ENST00000543304, ENST00000334805, ENST00000538536, ENST00000538437, ENST00000545082, | ENST00000278590, ENST00000528673, ENST00000453089, | |
| Fusion gene scores | * DoF score | 2 X 1 X 2=4 | 2 X 2 X 2=8 |
| # samples | 2 | 2 | |
| ** MAII score | log2(2/4*10)=2.32192809488736 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: STARD10 [Title/Abstract] AND ZC3H12C [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | KICH | TCGA-KL-8339-01A | STARD10 | chr11 | 72492020 | - | ZC3H12C | chr11 | 110007388 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000543304 | ENST00000278590 | STARD10 | chr11 | 72492020 | - | ZC3H12C | chr11 | 110007388 | + |
| Frame-shift | ENST00000543304 | ENST00000528673 | STARD10 | chr11 | 72492020 | - | ZC3H12C | chr11 | 110007388 | + |
| 5CDS-5UTR | ENST00000543304 | ENST00000453089 | STARD10 | chr11 | 72492020 | - | ZC3H12C | chr11 | 110007388 | + |
| In-frame | ENST00000334805 | ENST00000278590 | STARD10 | chr11 | 72492020 | - | ZC3H12C | chr11 | 110007388 | + |
| In-frame | ENST00000334805 | ENST00000528673 | STARD10 | chr11 | 72492020 | - | ZC3H12C | chr11 | 110007388 | + |
| 5CDS-5UTR | ENST00000334805 | ENST00000453089 | STARD10 | chr11 | 72492020 | - | ZC3H12C | chr11 | 110007388 | + |
| intron-3CDS | ENST00000538536 | ENST00000278590 | STARD10 | chr11 | 72492020 | - | ZC3H12C | chr11 | 110007388 | + |
| intron-3CDS | ENST00000538536 | ENST00000528673 | STARD10 | chr11 | 72492020 | - | ZC3H12C | chr11 | 110007388 | + |
| intron-5UTR | ENST00000538536 | ENST00000453089 | STARD10 | chr11 | 72492020 | - | ZC3H12C | chr11 | 110007388 | + |
| 5UTR-3CDS | ENST00000538437 | ENST00000278590 | STARD10 | chr11 | 72492020 | - | ZC3H12C | chr11 | 110007388 | + |
| 5UTR-3CDS | ENST00000538437 | ENST00000528673 | STARD10 | chr11 | 72492020 | - | ZC3H12C | chr11 | 110007388 | + |
| 5UTR-5UTR | ENST00000538437 | ENST00000453089 | STARD10 | chr11 | 72492020 | - | ZC3H12C | chr11 | 110007388 | + |
| intron-3CDS | ENST00000545082 | ENST00000278590 | STARD10 | chr11 | 72492020 | - | ZC3H12C | chr11 | 110007388 | + |
| intron-3CDS | ENST00000545082 | ENST00000528673 | STARD10 | chr11 | 72492020 | - | ZC3H12C | chr11 | 110007388 | + |
| intron-5UTR | ENST00000545082 | ENST00000453089 | STARD10 | chr11 | 72492020 | - | ZC3H12C | chr11 | 110007388 | + |
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FusionProtFeatures for STARD10_ZC3H12C |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| STARD10 | ZC3H12C |