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Fusion gene ID: 36266 |
FusionGeneSummary for ST7-OT4_ASZ1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ST7-OT4_ASZ1 | Fusion gene ID: 36266 | Hgene | Tgene | Gene symbol | ST7-OT4 | ASZ1 | Gene ID | 338069 | 136991 |
| Gene name | ST7 overlapping transcript 4 | ankyrin repeat, SAM and basic leucine zipper domain containing 1 | |
| Synonyms | NCRNA00042|ST7OT4 | ALP1|ANKL1|C7orf7|CT1.19|GASZ|Orf3 | |
| Cytomap | 7q31.2 | 7q31.2 | |
| Type of gene | ncRNA | protein-coding | |
| Description | ST7 overlapping transcript 4 (non-coding RNA)ST7 overlapping transcript 4 (non-protein coding) | ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1ankyrin-like 1ankyrin-like protein 1germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein | |
| Modification date | 20180329 | 20180523 | |
| UniProtAcc | Q8WWH4 | ||
| Ensembl transtripts involved in fusion gene | ENST00000397750, ENST00000466018, ENST00000397751, | ENST00000284629, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 5 X 3 X 3=45 |
| # samples | 1 | 3 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(3/45*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ST7-OT4 [Title/Abstract] AND ASZ1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LUAD | TCGA-86-8672-01A | ST7-OT4 | chr7 | 116595207 | + | ASZ1 | chr7 | 117025863 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000397750 | ENST00000284629 | ST7-OT4 | chr7 | 116595207 | + | ASZ1 | chr7 | 117025863 | - |
| 3UTR-3CDS | ENST00000466018 | ENST00000284629 | ST7-OT4 | chr7 | 116595207 | + | ASZ1 | chr7 | 117025863 | - |
| Frame-shift | ENST00000397751 | ENST00000284629 | ST7-OT4 | chr7 | 116595207 | + | ASZ1 | chr7 | 117025863 | - |
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FusionProtFeatures for ST7-OT4_ASZ1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ST7-OT4 | ASZ1 |