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Fusion gene ID: 36121 |
FusionGeneSummary for SSBP2_ANKRD36C |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SSBP2_ANKRD36C | Fusion gene ID: 36121 | Hgene | Tgene | Gene symbol | SSBP2 | ANKRD36C | Gene ID | 23635 | 400986 |
| Gene name | single stranded DNA binding protein 2 | ankyrin repeat domain 36C | |
| Synonyms | HSPC116|SOSS-B2 | - | |
| Cytomap | 5q14.1 | 2q11.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | single-stranded DNA-binding protein 2sequence-specific single-stranded-DNA-binding protein 2 | ankyrin repeat domain-containing protein 36Cprotein immuno-reactive with anti-PTH polyclonal antibodies | |
| Modification date | 20180523 | 20180403 | |
| UniProtAcc | P81877 | Q5JPF3 | |
| Ensembl transtripts involved in fusion gene | ENST00000320672, ENST00000509053, ENST00000514493, ENST00000510060, ENST00000505980, ENST00000515395, | ENST00000456556, ENST00000420871, ENST00000419039, ENST00000295246, | |
| Fusion gene scores | * DoF score | 7 X 6 X 5=210 | 1 X 1 X 1=1 |
| # samples | 7 | 1 | |
| ** MAII score | log2(7/210*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: SSBP2 [Title/Abstract] AND ANKRD36C [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | DR000829 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000320672 | ENST00000456556 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| 5CDS-intron | ENST00000320672 | ENST00000420871 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| 5CDS-intron | ENST00000320672 | ENST00000419039 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| 5CDS-intron | ENST00000320672 | ENST00000295246 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| Frame-shift | ENST00000509053 | ENST00000456556 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| 5CDS-intron | ENST00000509053 | ENST00000420871 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| 5CDS-intron | ENST00000509053 | ENST00000419039 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| 5CDS-intron | ENST00000509053 | ENST00000295246 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| Frame-shift | ENST00000514493 | ENST00000456556 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| 5CDS-intron | ENST00000514493 | ENST00000420871 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| 5CDS-intron | ENST00000514493 | ENST00000419039 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| 5CDS-intron | ENST00000514493 | ENST00000295246 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| intron-3CDS | ENST00000510060 | ENST00000456556 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| intron-intron | ENST00000510060 | ENST00000420871 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| intron-intron | ENST00000510060 | ENST00000419039 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| intron-intron | ENST00000510060 | ENST00000295246 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| Frame-shift | ENST00000505980 | ENST00000456556 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| 5CDS-intron | ENST00000505980 | ENST00000420871 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| 5CDS-intron | ENST00000505980 | ENST00000419039 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| 5CDS-intron | ENST00000505980 | ENST00000295246 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| Frame-shift | ENST00000515395 | ENST00000456556 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| 5CDS-intron | ENST00000515395 | ENST00000420871 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| 5CDS-intron | ENST00000515395 | ENST00000419039 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
| 5CDS-intron | ENST00000515395 | ENST00000295246 | SSBP2 | chr5 | 80911292 | - | ANKRD36C | chr2 | 96628295 | - |
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FusionProtFeatures for SSBP2_ANKRD36C |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SSBP2 | ANKRD36C |