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Fusion gene ID: 3609 |
FusionGeneSummary for AUH_CPM |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: AUH_CPM | Fusion gene ID: 3609 | Hgene | Tgene | Gene symbol | AUH | CPM | Gene ID | 549 | 1368 |
| Gene name | AU RNA binding methylglutaconyl-CoA hydratase | carboxypeptidase M | |
| Synonyms | - | - | |
| Cytomap | 9q22.31 | 12q15 | |
| Type of gene | protein-coding | protein-coding | |
| Description | methylglutaconyl-CoA hydratase, mitochondrial3-methylglutaconyl-CoA hydrataseAU RNA binding protein/enoyl-CoA hydrataseAU RNA-binding protein/enoyl-Coenzyme A hydrataseAU-binding protein/Enoyl-CoA hydrataseAU-specific RNA-binding enoyl-CoA hydratase | carboxypeptidase Mrenal carboxypeptidaseurinary carboxypeptidase B | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q13825 | P14384 | |
| Ensembl transtripts involved in fusion gene | ENST00000303617, ENST00000375731, ENST00000422391, ENST00000478465, | ENST00000546373, ENST00000551568, ENST00000338356, ENST00000549691, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 38 X 10 X 8=3040 |
| # samples | 1 | 35 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(35/3040*10)=-3.11864449649862 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: AUH [Title/Abstract] AND CPM [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-DX-A3M1-01A | AUH | chr9 | 94058303 | - | CPM | chr12 | 69265736 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000303617 | ENST00000546373 | AUH | chr9 | 94058303 | - | CPM | chr12 | 69265736 | - |
| Frame-shift | ENST00000303617 | ENST00000551568 | AUH | chr9 | 94058303 | - | CPM | chr12 | 69265736 | - |
| Frame-shift | ENST00000303617 | ENST00000338356 | AUH | chr9 | 94058303 | - | CPM | chr12 | 69265736 | - |
| 5CDS-intron | ENST00000303617 | ENST00000549691 | AUH | chr9 | 94058303 | - | CPM | chr12 | 69265736 | - |
| Frame-shift | ENST00000375731 | ENST00000546373 | AUH | chr9 | 94058303 | - | CPM | chr12 | 69265736 | - |
| Frame-shift | ENST00000375731 | ENST00000551568 | AUH | chr9 | 94058303 | - | CPM | chr12 | 69265736 | - |
| Frame-shift | ENST00000375731 | ENST00000338356 | AUH | chr9 | 94058303 | - | CPM | chr12 | 69265736 | - |
| 5CDS-intron | ENST00000375731 | ENST00000549691 | AUH | chr9 | 94058303 | - | CPM | chr12 | 69265736 | - |
| Frame-shift | ENST00000422391 | ENST00000546373 | AUH | chr9 | 94058303 | - | CPM | chr12 | 69265736 | - |
| Frame-shift | ENST00000422391 | ENST00000551568 | AUH | chr9 | 94058303 | - | CPM | chr12 | 69265736 | - |
| Frame-shift | ENST00000422391 | ENST00000338356 | AUH | chr9 | 94058303 | - | CPM | chr12 | 69265736 | - |
| 5CDS-intron | ENST00000422391 | ENST00000549691 | AUH | chr9 | 94058303 | - | CPM | chr12 | 69265736 | - |
| intron-3CDS | ENST00000478465 | ENST00000546373 | AUH | chr9 | 94058303 | - | CPM | chr12 | 69265736 | - |
| intron-3CDS | ENST00000478465 | ENST00000551568 | AUH | chr9 | 94058303 | - | CPM | chr12 | 69265736 | - |
| intron-3CDS | ENST00000478465 | ENST00000338356 | AUH | chr9 | 94058303 | - | CPM | chr12 | 69265736 | - |
| intron-intron | ENST00000478465 | ENST00000549691 | AUH | chr9 | 94058303 | - | CPM | chr12 | 69265736 | - |
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FusionProtFeatures for AUH_CPM |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| AUH | CPM |