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Fusion gene ID: 35906 |
FusionGeneSummary for SRBD1_MTMR7 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SRBD1_MTMR7 | Fusion gene ID: 35906 | Hgene | Tgene | Gene symbol | SRBD1 | MTMR7 | Gene ID | 55133 | 9108 |
| Gene name | S1 RNA binding domain 1 | myotubularin related protein 7 | |
| Synonyms | - | - | |
| Cytomap | 2p21 | 8p22 | |
| Type of gene | protein-coding | protein-coding | |
| Description | S1 RNA-binding domain-containing protein 1H_NH0576F01.1WUGSC:H_NH0576F01.1 | myotubularin-related protein 7 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q8N5C6 | Q9Y216 | |
| Ensembl transtripts involved in fusion gene | ENST00000263736, ENST00000535761, ENST00000490133, | ENST00000180173, ENST00000521857, ENST00000398099, ENST00000523571, | |
| Fusion gene scores | * DoF score | 5 X 4 X 3=60 | 2 X 2 X 1=4 |
| # samples | 4 | 2 | |
| ** MAII score | log2(4/60*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: SRBD1 [Title/Abstract] AND MTMR7 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AL117549 | SRBD1 | chr2 | 45789623 | - | MTMR7 | chr8 | 17161328 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000263736 | ENST00000180173 | SRBD1 | chr2 | 45789623 | - | MTMR7 | chr8 | 17161328 | + |
| intron-intron | ENST00000263736 | ENST00000521857 | SRBD1 | chr2 | 45789623 | - | MTMR7 | chr8 | 17161328 | + |
| intron-intron | ENST00000263736 | ENST00000398099 | SRBD1 | chr2 | 45789623 | - | MTMR7 | chr8 | 17161328 | + |
| intron-intron | ENST00000263736 | ENST00000523571 | SRBD1 | chr2 | 45789623 | - | MTMR7 | chr8 | 17161328 | + |
| intron-intron | ENST00000535761 | ENST00000180173 | SRBD1 | chr2 | 45789623 | - | MTMR7 | chr8 | 17161328 | + |
| intron-intron | ENST00000535761 | ENST00000521857 | SRBD1 | chr2 | 45789623 | - | MTMR7 | chr8 | 17161328 | + |
| intron-intron | ENST00000535761 | ENST00000398099 | SRBD1 | chr2 | 45789623 | - | MTMR7 | chr8 | 17161328 | + |
| intron-intron | ENST00000535761 | ENST00000523571 | SRBD1 | chr2 | 45789623 | - | MTMR7 | chr8 | 17161328 | + |
| intron-intron | ENST00000490133 | ENST00000180173 | SRBD1 | chr2 | 45789623 | - | MTMR7 | chr8 | 17161328 | + |
| intron-intron | ENST00000490133 | ENST00000521857 | SRBD1 | chr2 | 45789623 | - | MTMR7 | chr8 | 17161328 | + |
| intron-intron | ENST00000490133 | ENST00000398099 | SRBD1 | chr2 | 45789623 | - | MTMR7 | chr8 | 17161328 | + |
| intron-intron | ENST00000490133 | ENST00000523571 | SRBD1 | chr2 | 45789623 | - | MTMR7 | chr8 | 17161328 | + |
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FusionProtFeatures for SRBD1_MTMR7 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SRBD1 | MTMR7 |