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Fusion gene ID: 35260 |
FusionGeneSummary for SNX17_TXNL4B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SNX17_TXNL4B | Fusion gene ID: 35260 | Hgene | Tgene | Gene symbol | SNX17 | TXNL4B | Gene ID | 9784 | 54957 |
| Gene name | sorting nexin 17 | thioredoxin like 4B | |
| Synonyms | - | DLP|Dim2 | |
| Cytomap | 2p23.3 | 16q22.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | sorting nexin-17 | thioredoxin-like protein 4BDim1-like protein | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q15036 | Q9NX01 | |
| Ensembl transtripts involved in fusion gene | ENST00000233575, ENST00000543024, ENST00000537606, ENST00000542478, | ENST00000268483, ENST00000423037, ENST00000426362, | |
| Fusion gene scores | * DoF score | 2 X 2 X 1=4 | 3 X 3 X 1=9 |
| # samples | 2 | 3 | |
| ** MAII score | log2(2/4*10)=2.32192809488736 | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: SNX17 [Title/Abstract] AND TXNL4B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | DA980261 | SNX17 | chr2 | 27595535 | + | TXNL4B | chr16 | 72120550 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000233575 | ENST00000268483 | SNX17 | chr2 | 27595535 | + | TXNL4B | chr16 | 72120550 | - |
| Frame-shift | ENST00000233575 | ENST00000423037 | SNX17 | chr2 | 27595535 | + | TXNL4B | chr16 | 72120550 | - |
| Frame-shift | ENST00000233575 | ENST00000426362 | SNX17 | chr2 | 27595535 | + | TXNL4B | chr16 | 72120550 | - |
| intron-3CDS | ENST00000543024 | ENST00000268483 | SNX17 | chr2 | 27595535 | + | TXNL4B | chr16 | 72120550 | - |
| intron-3CDS | ENST00000543024 | ENST00000423037 | SNX17 | chr2 | 27595535 | + | TXNL4B | chr16 | 72120550 | - |
| intron-3CDS | ENST00000543024 | ENST00000426362 | SNX17 | chr2 | 27595535 | + | TXNL4B | chr16 | 72120550 | - |
| Frame-shift | ENST00000537606 | ENST00000268483 | SNX17 | chr2 | 27595535 | + | TXNL4B | chr16 | 72120550 | - |
| Frame-shift | ENST00000537606 | ENST00000423037 | SNX17 | chr2 | 27595535 | + | TXNL4B | chr16 | 72120550 | - |
| Frame-shift | ENST00000537606 | ENST00000426362 | SNX17 | chr2 | 27595535 | + | TXNL4B | chr16 | 72120550 | - |
| 5UTR-3CDS | ENST00000542478 | ENST00000268483 | SNX17 | chr2 | 27595535 | + | TXNL4B | chr16 | 72120550 | - |
| 5UTR-3CDS | ENST00000542478 | ENST00000423037 | SNX17 | chr2 | 27595535 | + | TXNL4B | chr16 | 72120550 | - |
| 5UTR-3CDS | ENST00000542478 | ENST00000426362 | SNX17 | chr2 | 27595535 | + | TXNL4B | chr16 | 72120550 | - |
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FusionProtFeatures for SNX17_TXNL4B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SNX17 | TXNL4B |