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Fusion gene ID: 35235 |
FusionGeneSummary for SNTG2_TRAPPC12 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SNTG2_TRAPPC12 | Fusion gene ID: 35235 | Hgene | Tgene | Gene symbol | SNTG2 | TRAPPC12 | Gene ID | 54221 | 51112 |
| Gene name | syntrophin gamma 2 | trafficking protein particle complex 12 | |
| Synonyms | G2SYN|SYN5 | CGI-87|PEBAS|TTC-15|TTC15 | |
| Cytomap | 2p25.3 | 2p25.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | gamma-2-syntrophinsyntrophin-5 | trafficking protein particle complex subunit 12TPR repeat protein 15tetratricopeptide repeat domain 15tetratricopeptide repeat protein 15trafficking of membranes and mitosis | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q9NY99 | Q8WVT3 | |
| Ensembl transtripts involved in fusion gene | ENST00000308624, ENST00000407292, ENST00000467759, | ENST00000382110, ENST00000324266, ENST00000469147, | |
| Fusion gene scores | * DoF score | 4 X 4 X 3=48 | 2 X 2 X 2=8 |
| # samples | 4 | 2 | |
| ** MAII score | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: SNTG2 [Title/Abstract] AND TRAPPC12 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | TRAPPC12 | GO:0051259 | protein complex oligomerization | 21525244 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | GBM | TCGA-06-0221-02A | SNTG2 | chr2 | 1206365 | + | TRAPPC12 | chr2 | 3461392 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000308624 | ENST00000382110 | SNTG2 | chr2 | 1206365 | + | TRAPPC12 | chr2 | 3461392 | + |
| intron-3CDS | ENST00000308624 | ENST00000324266 | SNTG2 | chr2 | 1206365 | + | TRAPPC12 | chr2 | 3461392 | + |
| intron-3UTR | ENST00000308624 | ENST00000469147 | SNTG2 | chr2 | 1206365 | + | TRAPPC12 | chr2 | 3461392 | + |
| intron-3CDS | ENST00000407292 | ENST00000382110 | SNTG2 | chr2 | 1206365 | + | TRAPPC12 | chr2 | 3461392 | + |
| intron-3CDS | ENST00000407292 | ENST00000324266 | SNTG2 | chr2 | 1206365 | + | TRAPPC12 | chr2 | 3461392 | + |
| intron-3UTR | ENST00000407292 | ENST00000469147 | SNTG2 | chr2 | 1206365 | + | TRAPPC12 | chr2 | 3461392 | + |
| 3UTR-3CDS | ENST00000467759 | ENST00000382110 | SNTG2 | chr2 | 1206365 | + | TRAPPC12 | chr2 | 3461392 | + |
| 3UTR-3CDS | ENST00000467759 | ENST00000324266 | SNTG2 | chr2 | 1206365 | + | TRAPPC12 | chr2 | 3461392 | + |
| 3UTR-3UTR | ENST00000467759 | ENST00000469147 | SNTG2 | chr2 | 1206365 | + | TRAPPC12 | chr2 | 3461392 | + |
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FusionProtFeatures for SNTG2_TRAPPC12 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SNTG2 | TRAPPC12 |