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Fusion gene ID: 35230 |
FusionGeneSummary for SNTB2_ZCRB1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SNTB2_ZCRB1 | Fusion gene ID: 35230 | Hgene | Tgene | Gene symbol | SNTB2 | ZCRB1 | Gene ID | 6645 | 85437 |
| Gene name | syntrophin beta 2 | zinc finger CCHC-type and RNA binding motif containing 1 | |
| Synonyms | D16S2531E|EST25263|SNT2B2|SNT3|SNTL | MADP-1|MADP1|RBM36|SNRNP31|ZCCHC19 | |
| Cytomap | 16q22.1 | 12q12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | beta-2-syntrophin59 kDa dystrophin-associated protein A1 basic component 2dystrophin-associated protein A1, 59kD, basic component 2syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)syntrophin-3 | zinc finger CCHC-type and RNA-binding motif-containing protein 1U11/U12 small nuclear ribonucleoprotein 31 kDa proteinU11/U12 snRNP 31 kDa proteinU11/U12 snRNP 31KU11/U12-31Kzinc finger CCHC-type and RNA binding motif 1 | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q13425 | Q8TBF4 | |
| Ensembl transtripts involved in fusion gene | ENST00000336278, ENST00000528525, | ENST00000266529, ENST00000552673, ENST00000551102, | |
| Fusion gene scores | * DoF score | 6 X 7 X 6=252 | 3 X 3 X 3=27 |
| # samples | 8 | 3 | |
| ** MAII score | log2(8/252*10)=-1.65535182861255 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: SNTB2 [Title/Abstract] AND ZCRB1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AI922257 | SNTB2 | chr16 | 69298590 | - | ZCRB1 | chr12 | 42707677 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000336278 | ENST00000266529 | SNTB2 | chr16 | 69298590 | - | ZCRB1 | chr12 | 42707677 | + |
| intron-intron | ENST00000336278 | ENST00000552673 | SNTB2 | chr16 | 69298590 | - | ZCRB1 | chr12 | 42707677 | + |
| intron-intron | ENST00000336278 | ENST00000551102 | SNTB2 | chr16 | 69298590 | - | ZCRB1 | chr12 | 42707677 | + |
| intron-intron | ENST00000528525 | ENST00000266529 | SNTB2 | chr16 | 69298590 | - | ZCRB1 | chr12 | 42707677 | + |
| intron-intron | ENST00000528525 | ENST00000552673 | SNTB2 | chr16 | 69298590 | - | ZCRB1 | chr12 | 42707677 | + |
| intron-intron | ENST00000528525 | ENST00000551102 | SNTB2 | chr16 | 69298590 | - | ZCRB1 | chr12 | 42707677 | + |
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FusionProtFeatures for SNTB2_ZCRB1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SNTB2 | ZCRB1 |