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Fusion gene ID: 3523 |
FusionGeneSummary for ATP9A_WFDC8 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ATP9A_WFDC8 | Fusion gene ID: 3523 | Hgene | Tgene | Gene symbol | ATP9A | WFDC8 | Gene ID | 10079 | 90199 |
| Gene name | ATPase phospholipid transporting 9A (putative) | WAP four-disulfide core domain 8 | |
| Synonyms | ATPIIA | C20orf170|HEL-S-292|WAP8|dJ461P17.1 | |
| Cytomap | 20q13.2 | 20q13.12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | probable phospholipid-transporting ATPase IIAATPase type IV, phospholipid-transporting (P-type),(putative)ATPase, class II, type 9Aphospholipid-transporting ATPase IIA | WAP four-disulfide core domain protein 8WAP motif protein 1epididymis secretory protein Li 292protease inhibitor WAP8putative protease inhibitor WAP8testicular secretory protein Li 68 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | O75110 | Q8IUA0 | |
| Ensembl transtripts involved in fusion gene | ENST00000311637, ENST00000338821, ENST00000402822, ENST00000477492, | ENST00000357199, ENST00000289953, | |
| Fusion gene scores | * DoF score | 9 X 8 X 7=504 | 1 X 1 X 1=1 |
| # samples | 9 | 1 | |
| ** MAII score | log2(9/504*10)=-2.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: ATP9A [Title/Abstract] AND WFDC8 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | COAD | TCGA-AD-6965-01A | ATP9A | chr20 | 50286536 | - | WFDC8 | chr20 | 44190858 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000311637 | ENST00000357199 | ATP9A | chr20 | 50286536 | - | WFDC8 | chr20 | 44190858 | - |
| Frame-shift | ENST00000311637 | ENST00000289953 | ATP9A | chr20 | 50286536 | - | WFDC8 | chr20 | 44190858 | - |
| In-frame | ENST00000338821 | ENST00000357199 | ATP9A | chr20 | 50286536 | - | WFDC8 | chr20 | 44190858 | - |
| Frame-shift | ENST00000338821 | ENST00000289953 | ATP9A | chr20 | 50286536 | - | WFDC8 | chr20 | 44190858 | - |
| In-frame | ENST00000402822 | ENST00000357199 | ATP9A | chr20 | 50286536 | - | WFDC8 | chr20 | 44190858 | - |
| Frame-shift | ENST00000402822 | ENST00000289953 | ATP9A | chr20 | 50286536 | - | WFDC8 | chr20 | 44190858 | - |
| intron-3CDS | ENST00000477492 | ENST00000357199 | ATP9A | chr20 | 50286536 | - | WFDC8 | chr20 | 44190858 | - |
| intron-3CDS | ENST00000477492 | ENST00000289953 | ATP9A | chr20 | 50286536 | - | WFDC8 | chr20 | 44190858 | - |
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FusionProtFeatures for ATP9A_WFDC8 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ATP9A | WFDC8 |