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Fusion gene ID: 35214 |
FusionGeneSummary for SNRPN_RREB1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SNRPN_RREB1 | Fusion gene ID: 35214 | Hgene | Tgene | Gene symbol | SNRPN | RREB1 | Gene ID | 6638 | 6239 |
| Gene name | small nuclear ribonucleoprotein polypeptide N | ras responsive element binding protein 1 | |
| Synonyms | HCERN3|PWCR|RT-LI|SM-D|SMN|SNRNP-N|SNURF-SNRPN|sm-N | FINB|HNT|LZ321|RREB-1|Zep-1 | |
| Cytomap | 15q11.2 | 6p24.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | small nuclear ribonucleoprotein-associated protein NSM protein Nsm protein Dtissue-specific splicing protein | ras-responsive element-binding protein 1DNA-binding proteinfinger protein in nuclear bodieshindsight homolograf-responsive zinc finger protein LZ321zinc finger motif enhancer-binding protein 1 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P63162 | Q92766 | |
| Ensembl transtripts involved in fusion gene | ENST00000400098, ENST00000400100, ENST00000400097, ENST00000553597, ENST00000390687, ENST00000346403, ENST00000554227, ENST00000577565, ENST00000444203, | ENST00000379933, ENST00000379938, ENST00000334984, ENST00000349384, | |
| Fusion gene scores | * DoF score | 10 X 13 X 2=260 | 9 X 7 X 4=252 |
| # samples | 14 | 9 | |
| ** MAII score | log2(14/260*10)=-0.893084796083488 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/252*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SNRPN [Title/Abstract] AND RREB1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | RREB1 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 8816445 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | T19462 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000400098 | ENST00000379933 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000400098 | ENST00000379938 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000400098 | ENST00000334984 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000400098 | ENST00000349384 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-intron | ENST00000400100 | ENST00000379933 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000400100 | ENST00000379938 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000400100 | ENST00000334984 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000400100 | ENST00000349384 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-intron | ENST00000400097 | ENST00000379933 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000400097 | ENST00000379938 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000400097 | ENST00000334984 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000400097 | ENST00000349384 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| intron-intron | ENST00000553597 | ENST00000379933 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| intron-5UTR | ENST00000553597 | ENST00000379938 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| intron-5UTR | ENST00000553597 | ENST00000334984 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| intron-5UTR | ENST00000553597 | ENST00000349384 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-intron | ENST00000390687 | ENST00000379933 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000390687 | ENST00000379938 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000390687 | ENST00000334984 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000390687 | ENST00000349384 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-intron | ENST00000346403 | ENST00000379933 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000346403 | ENST00000379938 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000346403 | ENST00000334984 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000346403 | ENST00000349384 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-intron | ENST00000554227 | ENST00000379933 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000554227 | ENST00000379938 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000554227 | ENST00000334984 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000554227 | ENST00000349384 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-intron | ENST00000577565 | ENST00000379933 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000577565 | ENST00000379938 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000577565 | ENST00000334984 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000577565 | ENST00000349384 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-intron | ENST00000444203 | ENST00000379933 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000444203 | ENST00000379938 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000444203 | ENST00000334984 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
| 5CDS-5UTR | ENST00000444203 | ENST00000349384 | SNRPN | chr15 | 25223436 | + | RREB1 | chr6 | 7108259 | + |
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FusionProtFeatures for SNRPN_RREB1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SNRPN | RREB1 |