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Fusion gene ID: 35139 |
FusionGeneSummary for SNHG3_PGA3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SNHG3_PGA3 | Fusion gene ID: 35139 | Hgene | Tgene | Gene symbol | SNHG3 | PGA3 | Gene ID | 8420 | 643834 |
| Gene name | small nucleolar RNA host gene 3 | pepsinogen 3, group I (pepsinogen A) | |
| Synonyms | NCRNA00014|RNU17C|RNU17D|U17HG|U17HG-A|U17HG-AB | - | |
| Cytomap | 1p35.3 | 11q12.2 | |
| Type of gene | ncRNA | protein-coding | |
| Description | U17 small nucleolar RNA hostsmall nucleolar RNA host gene (non-protein coding) 3small nucleolar RNA host gene 3 (non-protein coding) | pepsin A-3pepsinogen A3pepsinogen-3 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | P0DJD8 | ||
| Ensembl transtripts involved in fusion gene | ENST00000364938, | ENST00000325558, ENST00000543125, ENST00000538258, | |
| Fusion gene scores | * DoF score | 15 X 7 X 4=420 | 8 X 7 X 3=168 |
| # samples | 15 | 7 | |
| ** MAII score | log2(15/420*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/168*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SNHG3 [Title/Abstract] AND PGA3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LUAD | TCGA-38-4629-01A | SNHG3 | chr1 | 28834672 | + | PGA3 | chr11 | 60977314 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000364938 | ENST00000325558 | SNHG3 | chr1 | 28834672 | + | PGA3 | chr11 | 60977314 | + |
| intron-3CDS | ENST00000364938 | ENST00000543125 | SNHG3 | chr1 | 28834672 | + | PGA3 | chr11 | 60977314 | + |
| intron-intron | ENST00000364938 | ENST00000538258 | SNHG3 | chr1 | 28834672 | + | PGA3 | chr11 | 60977314 | + |
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FusionProtFeatures for SNHG3_PGA3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SNHG3 | PGA3 |